Discovery of N‑Substituted Acetamide Derivatives as Promising P2Y₁₄R Antagonists Using Molecular Hybridization Based on Crystallographic Overlay by Wenjin Liu (4016060)

“…Thus, compound <b>I-17</b>, with potent P2Y₁₄R antagonistic activity, <i>in vitro</i> and <i>in vivo</i> efficacy, and favorable bioavailability (<i>F</i> = 75%), could be a promising lead compound for acute gouty arthritis.…”

Discovery of N‑Substituted Acetamide Derivatives as Promising P2Y₁₄R Antagonists Using Molecular Hybridization Based on Crystallographic Overlay by Wenjin Liu (4016060)

“…Thus, compound <b>I-17</b>, with potent P2Y₁₄R antagonistic activity, <i>in vitro</i> and <i>in vivo</i> efficacy, and favorable bioavailability (<i>F</i> = 75%), could be a promising lead compound for acute gouty arthritis.…”

Predicted <i>cis</i>-acting elements in <i>DpAP2</i> promoter. by Lingru Ruan (18995544)

“…<i>parva</i> cells treated with different concentrations of MeJA (10, 20, 50, 100 μM) and GA3 (10, 20, 50, 100 μM). The high concentrations of MeJA (10–100 μM) inhibited the accumulation of carotenoid, and the relative expression of <i>DpAP2</i>, <i>PSY</i>, <i>PDS</i> and <i>GGPS</i> decreased significantly. …”

AS-IV inhibits the expression of inflammatory factors in rats with LPS-induced ALI. by Cheng Luo (48047)

Serum EVs of iFIRKO mice promote hepatocyte proliferation <i>in vitro</i>. by Yoshihiro Niitsu (14249456)

Relative abundance of <i>Ae</i>. <i>albopictus</i> and other species recovered from ovitraps. by Judicaël Obame-Nkoghe (3512054)

Dynamics of phospholipids at different stages during microspore embryogenesis of <i>Brassica napus</i>. by Xin-Qiao Du (13150022)

Characterization of fecal steroid profiles bison, elk, moose, mule deer, and pronghorn based on the relative abundances of sterols, stanols, and stanones and bile acids in individu... by John A. F. Wendt (19976392)

Temsirolimus increases progerin clearance via autophagy. by Diana Gabriel (3608093)

Shrimp allergen extract (SAE) immunotherapy preventing the development of allergies. by Honey Dzikri Marhaeny (20480031)

“…SAE desensitization successfully decreased transcription of (A) <i>FcεR1α</i> mRNA (n = 6 mice per group) and (B) IL-4 mRNA—relative to NC—in the ileal tissue (n = 3 mice per group), and suppressed the production of the pro-inflammatory cytokine (C) IL-4 in serum (n = 6 mice per group). …”

The Combination of Quantitative Proteomics and Systems Genetics Analysis Reveals that PTN Is Associated with Sleep-Loss-Induced Cognitive Impairment by Yutong Zhou (5492852)

Correlations among clinical illness signs. by Aiden E. Juge (12986438)

Analysis of MD simulations for the SP domain of native PC and its mutant structures (L305R, W342C, G403R, V420E, and W444C) over 200 ns simulations. by Mahvash Farajzadeh-Dehkordi (17468232)

Mild hypoxic-ischemic encephalopathy piglet model. by Dawn B. Lammert (21175128)

Imbalanced Dataset Distribution. by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”

Data Preprocessing Steps for IDC Dataset. by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”

Flowchart of Proposed SMO_CNN. by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”

IDC Breast Cancer Dataset Descriptions. by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”

Accuracy Graph. by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”

Loss Graph. by Mudhafar Jalil Jassim Ghrabat (22177655)

“…We surpassing other models as such, CNN, VGG19, ResNet50.</p></div>…”