NF-κB p65 and phosphorylation of IκBα <i>in vitro</i>. by Naoki Takada (2728912)

“…<p>(A) The enzyme-linked immunosorbent assay (ELISA) results showed that p65 concentration in the radiation group was higher than that in the control group (NOZ: 2,398.4 ± 62.8 ng/mg protein vs. 923.5 ± 42.3 ng/mg protein, p < 0.01; OCUG-1: 2,609.3 ± 409.3 ng/mg protein vs. 1,899.5 ± 99.5 ng/mg protein, p < 0.05). p65 concentration in the combination group was lower than that in the radiation group (NOZ: 1,256.1 ± 13.0 ng/mg protein vs. 2,398.4 ± 62.8 ng/mg protein, p < 0.01; OCUG-1: 1,250.9 ± 117.8 ng/mg protein vs. 2,609.3 ± 409.3 ng/mg protein, p < 0.01). …”

Efficacy of SGLT2 inhibitors for anthracycline-induced cardiotoxicity: a meta-analysis in cancer patients by Sana Mohsin (19773969)

“…</p> <p><b>Results:</b> 3 cohort studies were identified, analyzing 2817 patients. Results display a significant reduction in overall mortality [RR = 0.52 (0.33–0.82); <i>p</i> = 0.005; I²= 32%], HF hospitalization [RR = 0.20 (0.04–1.02); <i>p</i> = 0.05; I²= 0%] and no significant reduction in HF incidence [RR = 0.50 (0.20–1.16); <i>p</i> = 0.11, I²= 0%].…”

Mitotic regeneration of IPhCs. by Tomokatsu Udagawa (11675636)

“…(O) Significantly more EdU⁺ Sox2⁺ cells were detected throughout the P7 IPhC regions of DT-treated <i>Lgr5</i>^<i>DTR/+</i> cochlea relative to controls, decreasing in an apical–basal gradient. …”

The Efficacy of Hyperbaric Oxygen Therapy on Middle Cerebral Artery Occlusion in Animal Studies: A Meta-Analysis by Yang Xu (178421)

“…Subgroup analysis showed that a maximal neuro-protective effect was reached when HBO was administered immediately after MCAO with an absolute atmospheric pressure (ATA) of 2.0 (50% decrease; 95% CI, 43% -57% decrease; <i>p</i> < 0.0001) and more than 6 hours HBO treatment (53% decrease; 95% CI, 41% -64% decrease; <i>p</i> = 0.0005).…”

Data_Sheet_1_Mindfulness Training for Primary Care for Portuguese-Speaking Immigrants: A Pilot Study.docx by Marcelo Trombka (11411288)

“…All survey finishers would recommend the program to a friend, found the program helpful, and rated the overall program as “very good” or “excellent,” and 93% would participate again, with satisfaction mean scores between 4.6 and 5 (Likert scale 0–5). …”

Statin Effects on Aggression: Results from the UCSD Statin Study, a Randomized Control Trial by Beatrice A. Golomb (140574)

“…</p><p>Trial Registration</p><p>Clinicaltrials.gov <a href="https://clinicaltrials.gov/ct2/show/NCT00330980" target="_blank">NCT00330980</a></p></div>…”

Table_1_Clinical Characteristics and Immune Responses of 137 Deceased Patients With COVID-19: A Retrospective Study.docx by Ning Cui (502137)

“…Our analysis revealed that age ≥ 65 years, male sex, malignancy, chronic obstructive pulmonary disease, dyspnea, dizziness, respiratory rate > 20 bpm, heart rate > 100 bpm, systolic blood pressure < 90 mmHg, neutrophils > 6.3×109/L, lymphopenia, thrombocytopenia, D-dimer ≥ 0.5 mg/L, lactate dehydrogenase > 250 U/L, aspartate aminotransferase > 40 U/L, total bilirubin > 26 μmol/L, albumin < 35 g/L, blood urea nitrogen > 9.5 mmol/L, estimated glomerular filtration rate < 90 ml/min/1.73, elevated cardiac troponin I, N-terminal pro-brain natriuretic peptide ≥ 900 pg/ml, C-reactive protein ≥ 25 mg/L, procalcitonin ≥ 0.05 ng/ml and ferritin > 400 μg/L were associated with death in patients with COVID-19. …”

Nanocomposite Grafted Stretchable and Conductive Ionic Hydrogels for Use as Soft Electrode in a Wearable Electrocardiogram Monitoring Device by Subhankar Mandal (8215980)

“…The UTS of hydrogels was dependent on the size of Ag NP in PAHz–Ag NCs, and the value increased from 0.70 to 1.14 MPa with the decrease in Ag NP size from ∼40 to 5 nm. The hydrogel samples exhibited adequate skin adhesiveness (tack adhesive strength ≈10.8 kPa), conductivity (50.5 mS/cm), and strain sensing ability (gauge factor ≈0.9), suggesting these samples are potentially useful for various soft electronics applications. …”

Nanocomposite Grafted Stretchable and Conductive Ionic Hydrogels for Use as Soft Electrode in a Wearable Electrocardiogram Monitoring Device by Subhankar Mandal (8215980)

“…The UTS of hydrogels was dependent on the size of Ag NP in PAHz–Ag NCs, and the value increased from 0.70 to 1.14 MPa with the decrease in Ag NP size from ∼40 to 5 nm. The hydrogel samples exhibited adequate skin adhesiveness (tack adhesive strength ≈10.8 kPa), conductivity (50.5 mS/cm), and strain sensing ability (gauge factor ≈0.9), suggesting these samples are potentially useful for various soft electronics applications. …”

Average methylation and coverage across technologies. by Amy Longtin (21409957)

Developmental and Neurobehavioral Toxicity of Hexaphenoxycyclotriphosphazene: Implications for Its Safety as a Flame-Retardant Alternative to Triphenyl Phosphate by Ruobing Bai (4860043)

“…HPCTP caused dose-dependent depression-like behaviors (hypoactivity, light-zone avoidance) through suppression of serotonin 1A (5-HT₁A) signaling, supported by decreased <i>htr1aa</i> expression and serotonin levels and partially rescued by the 5-HT₁A receptor agonist 8-OH-DPAT. …”

Neutralization of point mutants of B.1.351 and D614G spike-pseudotyped lentiviral particles by convalescent plasmas from B.1.351 and early 2020-infected individuals. by Allison J. Greaney (11046384)

“…<b>(B)</b> The fold-decrease in neutralization for samples shown in <b><a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1010248#ppat.1010248.g005" target="_blank">Fig 5</a></b>, with the addition of previously measured neutralization by samples from 6 early 2020 convalescent individuals collected approximately 100 days post-symptom onset [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1010248#ppat.1010248.ref038" target="_blank">38</a>]. …”

A reduction in brain mass and cortical volume seen in the adult <i>Cln6^nclf</i> mouse. by Jeremy P. Morgan (479017)

“…<p>Brain mass was assessed in the <i>Cln6^nclf</i>, as a decrease in brain mass is often seen in vLINCL patients. …”

Postprandial changes in (A) serum free fatty acid and (B) cortisol after mood inductions. by Ilse C. Schrieks (512142)

Average behaviour of Tajima’s <i>D</i> during a crash and recovery in parasite prevalence. by Jason A. Hendry (11302608)

Frequency trajectories of iSNVs that fluctuated (Top) and their positions on the genome (Bottom) (patients A-I). by Lele Zhao (532080)

“…<p>The inclusion criterion was iSNVs that changed from below 50% at Baseline (i.e., 0 days post baseline), to above 50% at PT12 (12 weeks post treatment), and decreased to below 50% at PT24 (24 weeks post treatment). …”

New advances in <i>DPYD</i> genotype and risk of severe toxicity under capecitabine - Fig 3 by Marie-Christine Etienne-Grimaldi (413881)

“…<p>Distribution of pre-treatment plasma UH2/U ratio (A) and Uracil concentrations (B) for the 205 patients with validated phenotypic data, according to <i>DPYD</i> variants of interest: variant *2A (3 heterozygous patients), D949V (3 heterozygous patients), R592W (1 heterozygous patient), D342G (1 heterozygous patient), HapB3 (4 heterozygous patients), 166VV (3 homozygous patients) <i>vs</i> any other variations (185 patients) <i>vs</i> no variation (5 patients). …”

Adverse event list. by Stefan Halbherr (21353882)

“…</p><p>Non-motor symptoms of PD, motor parkinsonian signs off medication, and quality of life improved significantly during the treatment phase, including the MDS-UPDRS total score (mean decrease −11.09; 95% Confidence Interval [CI]; −18, −4.1; <i>p</i> = 0.006), the Parkinson’s disease Questionnaire-39 (PDQ-39) summary index (mean decrease −2.91; 95% CI; −4.4, −1.4; <i>p</i> = 0.005), and the Non-Motor Symptoms Questionnaire (NMS-Quest) (mean decrease −4.27; 95% CI; −6.5, −2.1; <i>p</i> = 0.009). …”

Patient characteristics. by Stefan Halbherr (21353882)

“…</p><p>Non-motor symptoms of PD, motor parkinsonian signs off medication, and quality of life improved significantly during the treatment phase, including the MDS-UPDRS total score (mean decrease −11.09; 95% Confidence Interval [CI]; −18, −4.1; <i>p</i> = 0.006), the Parkinson’s disease Questionnaire-39 (PDQ-39) summary index (mean decrease −2.91; 95% CI; −4.4, −1.4; <i>p</i> = 0.005), and the Non-Motor Symptoms Questionnaire (NMS-Quest) (mean decrease −4.27; 95% CI; −6.5, −2.1; <i>p</i> = 0.009). …”

Quantitative image analysis metrics for the 3D gridded reconstruction (SIMBA) in red, the motion-resolved reconstruction (XD-SIMBA) in purple, the motion-resolved reconstruction wi... by Ludovica Romanin (18824043)