Red Blood Cell Transfusion and Mortality in Trauma Patients: Risk-Stratified Analysis of an Observational Study by Pablo Perel (102217)

“…Transfusion was associated with an increase in all-cause mortality among patients with &lt;6% and 6%–20% predicted risk of death (odds ratio [OR] 5.40, 95% CI 4.08–7.13, <i>p&lt;</i>0.0001, and OR 2.31, 95% CI 1.96–2.73, <i>p&lt;</i>0.0001, respectively), but with a decrease in all-cause mortality in patients with &gt;50% predicted risk of death (OR 0.59, 95% CI 0.47–0.74, <i>p&lt;</i>0.0001). …”

Data_Sheet_1_Molybdenum and Cadmium Co-induce Mitochondrial Quality Control Disorder via FUNDC1-Mediated Mitophagy in Sheep Kidney.doc by Yunhui Wu (2995374)

“…Forty-eight 2-month-old sheep were stochastically divided into four groups, as shown below: control group, Mo [45 mg/kg body weight (BW)] group, Cd (1 mg/kg BW) group and Mo (45 mg/kg BW)+Cd (1 mg/kg BW) group, with 50 days feed technique. The results showed that Mo or/and Cd attract an unbalance of trace minerals and vacuoles and granular degeneration of renal tubular epithelial cells, and increase the number of mitophagosomes and vacuole-mitochondria and LC3 puncta and MDA and H₂O₂ contents, and decrease ATP content in the kidney. …”

<strong>Drought re-routes soil microbial carbon metabolism towards emission of volatile metabolites in an artificial tropical rainforest</strong> by Linnea Honeker (13113813)

“…After gas fluxes were expected to equilibrate, approximately 8 hr post pyruvate labeling (~ 6 PM), measurement intervals were decreased to low frequency (50 minutes) and remained at this frequency until measurements were stopped at 48 hr post labeling. …”

Depletion of free PI(3)P, PI(4,5)P₂ and PI(3,4,5)P₃ binding sites in <i>G</i>. <i>lamblia</i> trophozoites elicits uptake and morphological phenotypes. by Lenka Cernikova (2885315)

Equilibrium binding of single strand DNA (P1) from promoter with mNdK by Praveen Kumar (8242)

“…CD spectra of P1 (4 μM) shows decrease in ellipticity at 285 nm with increasing mNdK (0–0.5 μM) in 50 mM Tris-MES-acetate pH 6.5, 1 mM MgCl, 75 mM NaCl within 30 min of incubation, after each addition, at 37°C. () Enzymatic (phosphotransfer) activity of mNdK at pH 6.5. …”

HepR21 cells have increased resilience to nutrient deprivation compared to HepG2 cells. by Paramita Saha (473954)

“…A set of cells were kept as control. The survivability of HepR21 cells was found to remain unaffected while HepG2 cells were highly sensitive upon prolonged starvation with an overall 50% decrease in growth after 36 h of starvation. …”

In-vitro Antibacterial and Antibiofilm Activity of Cinnamomum verum Leaf Oil against Pseudomonas aeruginosa, Staphylococcus aureus and Klebsiella pneumoniae by GAYAN K. WIJESINGHE (10365978)

“…Minimum Biofilm Inhibitory and Biofilm Eradication Concentrations (MBIC50 and MBEC) were 1.0 and 4.0 mg/mL. SEM indicated cellular shrinkages, cell wall damages, and decreased biofilm densities. …”

Video_1_Robustness and Scalability of Regional Climate Projections Over Europe.mp4 by Dominic Matte (6270914)

“…<p>Climate change projections for Europe consistently indicate a future decrease in summer precipitation over southern Europe and an increase over northern Europe. …”

Forage yield and structural responses of spineless cactus ‘Orelha de Elefante Mexicana’ at different planting densities by Juliana de Souza Pereira (10442366)

“…The evaluated densities were 20,000; 25,000; 33,333; 50,000; and 100,000 plants ha-1. The increase in planting density caused a linear reduction in plant height, width, and mass, as well as in number of primary, secondary, tertiary, and overall cladodes. …”

Increased proteolysis of YY1 is observed in post-mortem Alzheimer’s disease (AD) brain tissue. by Soline Aubry (507157)

“…Densitometric analysis of immunoblots from BA38 shows (<i>C</i>) a significant decrease (<i>p</i> = 0.02) in the full-length YY1 protein (60 kDa) in AD (<i>n</i> = 15, mAD + sAD) and (<i>D</i>) a significant increase (<i>p</i> = 0.002) in the proportion of proteolytic fragments (35–50 kDa) compared to controls (<i>n</i> = 9). …”

NF-κB activity is required for head formation. by Neil J. Armstrong (323599)

“…(<b>D</b>) Graphical representation of dorsoanterior index (DAI) of control embryos (blue columns) versus embryos injected dorsally with 50 pg of ΔNIκBα (red columns). (<b>E</b>) Time course analysis of embryos injected dorsally with a total of 500 pg ΔNIκBα RNA at the two, four, eight, 16- and 32-cell stage; the accompanying decrease in cell size was compensated by injecting multiple dorsal cells from the 8-cell stage on (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0036136#s4" target="_blank">materials and methods</a>). …”

Accelerated Immunodeficiency by Anti-CCR5 Treatment in HIV Infection by Ariel D. Weinberger (169848)

“…The model shows that the R5-to-X4 switch occurs as CD4⁺ T cell activation levels increase above a threshold and as CD4⁺ T cell counts decrease below a threshold during late-stage HIV infection. …”

Table_2_Small molecules to regulate the GH/IGF1 axis by inhibiting the growth hormone receptor synthesis.xlsx by Lieke M. van der Velden (8841629)

“…In preclinical xenografted experiments, BM001 showed a strong decrease in tumor volume in mice transplanted with MDA‐MB‐231 breast cancer cells. …”

Supplementary Material for: Effect of Dupilumab on Depression in Asthma with Eosinophilic Chronic Rhinosinusitis in the Japanese Population by Koya T. (4155160)

“…In the evaluation 4 months after dupilumab treatment, the PHQ-9 score was significantly reduced, and the decrease was remarkable in patients whose nasal symptom score was reduced by 50% or more. …”

Video_2_Robustness and Scalability of Regional Climate Projections Over Europe.MP4 by Dominic Matte (6270914)

“…<p>Climate change projections for Europe consistently indicate a future decrease in summer precipitation over southern Europe and an increase over northern Europe. …”

Impaired Sprouting and Axonal Atrophy in Cerebellar Climbing Fibres following <em>In Vivo</em> Silencing of the Growth-Associated Protein GAP-43 by Giorgio Grasselli (217929)

“…We show that lack of GAP-43 causes an atrophy of the CF in non-traumatic conditions, consisting in a decrease of its length, branching and number of synaptic boutons. …”

PHOSPHORUS FERTILIZATION AND SOIL TEXTURE AFFECT POTATO YIELD by JÉSSYCA DELLINHARES LOPES MARTINS (6117419)

“…<div><p>ABSTRACT Potato (Solanum tuberosum L.) is a nutritionally demanding crop, and phosphorus (P) is a nutrient that exerts a large effect on tuber yield. …”

Table_1_Small molecules to regulate the GH/IGF1 axis by inhibiting the growth hormone receptor synthesis.xlsx by Lieke M. van der Velden (8841629)

“…In preclinical xenografted experiments, BM001 showed a strong decrease in tumor volume in mice transplanted with MDA‐MB‐231 breast cancer cells. …”

SamOtos_withStrayAssignment.csv from High dispersal rates in hybrids drive expansion of maladaptive hybridization by Samuel L. Bourret (13997720)

“…Hybridization between native and invasive species, a major cause of biodiversity loss, can spread rapidly even when hybrids have reduced fitness. …”

Large Reverse Saturable Absorption at the Sunlight Power Level Using the Ultralong Lifetime of Triplet Excitons by Shuzo Hirata (1298562)

“…The efficient accumulation of the triplet excitons and high σ₃₄ – σ₀₁ led to an onset of the RSA characteristics under irradiance below 10^–1 mW cm^–2. A film of the amorphous material showed a large decrease of transmittance from 66% at 0.02 mW cm^–2 to 24% at 50 mW cm^–2 for continuous light at 405 nm.…”