Episode Four: Student engagement: Meeting current needs and developing sustainable approaches by Thomas Cochrane (9725291)

Supplementary Material for: Therapeutic Effects of Add-On Tenapanor for Hemodialysis Patients with Refractory Hyperphosphatemia by Shigematsu T. (4106377)

“…<b><i>Results:</i></b> In total, 24 patients were randomly assigned to the placebo group and 23 to the tenapanor group. The mean serum phosphorus level decreased from 7.01 mg/dL on day 1 to 6.69 mg/dL on day 43 in the placebo group and from 6.77 mg/dL on day 1 to 4.67 mg/dL on day 43 in the tenapanor group. …”

Optimization of the Malachite-Green ATPase assay for EHD4^ΔN. by Saif Mohd (19251157)

“…<b>B</b> MLG-based ATPase assays for 4 μM EHD4^ΔN, 500 μg/ml DOPS and 50 μM ATP were done at 37°C and 30°C. A further decrease to 25°C did not affect the enzymatic activity compared to 30°C (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0302704#pone.0302704.s002" target="_blank">S2I Fig</a>). …”

Mu opioid agonist-induced [³⁵S]-GTPγS binding is comparable on spinal cord membrane preparation from mu-cKO and mu^fl mice. by Raphaël Weibel (458030)

“…Results are presented as means ± sem of 5-6 experiments on 5 distinct membrane preparations. ★★★ <i>P</i><0.001, ★ <i>P</i><0.05 50%-50% mu-cKO, mu^fl or 50%-50% mix <i>vs</i> mu-KO, Student t-test.…”

Enhancing 7-dehydrocholesterol suppresses brain ferroptosis and tissue injury after neonatal hypoxia-ischemia by Thiago C. Genaro-Mattos (16385144)

“…MDA levels assessed by TBARS are decreased in animals treated with CAR, indicating that CAR treatment decreases markers of phospholipid oxidation. …”

Supplementary Material.docx by Fabrice Roda (17861195)

mIMCD-3 cells as an <i>in vitro</i> model to examine target genes of endogenous tRA/RARs. by Yuen Fei Wong (133656)

“…</b> Treating cells with 1 µM AGN193109 for 24 h resulted in a decrease of RARE-luciferase activity to about 50% of that of the vehicle control group; the reduction was at least partially abolished with simultaneous addition of exogenous tRA at 0.01–1 µM, in a dose-dependent manner. ** and ***: p<0.01 and p<0.001, respectively. …”

Supplementary Material for: Differentiating ischemic optic neuropathy from glaucoma using diagnostic tests by Smeets F. (17818949)

Sufficiently high Arp2/3 density is required to maintain the continuity of branched network architecture. by June Hyung Kim (22386484)

Results of linear models testing variation in different measures of plant response to competition. by Lena Neuenkamp (6941123)

Screening TAS2R5 agonists for the receptor downregulation response to long- term agonist exposure. by Donghwa Kim (252081)

“…<p>HEK-293T cells stably expressing FLAG-tagged TAS2R5 were exposed in culture for 18 hrs to the indicated agonists at a concentration 10-fold greater than their functional EC₅₀ values. …”

Reversal of pathology in I2S knockout (mucopolysaccharidosis II) mice after three IT-lumbar injections of I2S. by Pericles Calias (334957)

Time Since Deposition Signatures for the Analysis of Canine Body Fluid by Alysia Townsley (20673209)

“…<p dir="ltr">Although dogfighting is a felony in all 50 states, it has grown into a substantial enterprise that is often tied to other organized crime activities including gambling, narcotics, and weapons trafficking. …”

Under-Dominance Constrains the Evolution of Negative Autoregulation in Diploids by Alexander J. Stewart (392679)

Model for Condensin II–mediated chromosome territory formation. by Christopher R. Bauer (139136)

μCT analysis of organotypic cultured embryonic femurs (E13) in basal and TGF-β3 conditions. by Emma L. Smith (716897)

“…<p><i>A</i>, μCT images (whole femur tissue; saggital sections; segmented mineralized bone (green); and cross sectional sections of the central diaphysis region) of the embryonic chick femurs (E13) organotypic cultured in basal and TGF-β3 (5ng/ml and 15ng/ml) for 10 days. <i>B</i>, Femur lengths; Values are means ± s.d. …”

Global Profiling of Alternative Splicing Events and Gene Expression Regulated by hnRNPH/F by Erming Wang (110480)

“…<div><p>In this study, we have investigated the global impact of heterogeneous nuclear Ribonuclear Protein (hnRNP) H/F-mediated regulation of splicing events and gene expression in oligodendrocytes. …”

Nuclear Glycolytic Enzyme Enolase of <i>Toxoplasma gondii</i> Functions as a Transcriptional Regulator by Thomas Mouveaux (226120)

“…Using a ChIP-Seq technique, we provide evidence for TgENO2 enrichment at the 5′ untranslated gene regions containing the putative promoters of 241 nuclear genes. …”

Image_1_Inducible Rpt3, a Proteasome Component, Knockout in Adult Skeletal Muscle Results in Muscle Atrophy.pdf by Yasuo Kitajima (3493466)

“…The Rpt3-knockout mice showed a significant reduction by more than 90% in the expression of Rpt3 in adult muscles. Using this model, we found that proteasome dysfunction in adult muscles resulted in muscle wasting and a decrease in the myofiber size. …”

Data_Sheet_1_Single-cell magnetotaxis in mucus-mimicking polymeric solutions.PDF by Brianna Bradley (19169287)

“…The swimming speeds increase from 44.0 ± 13.6 μm/s in 0 mg/mL of PAM to 52.73 ± 15.6 μm/s in 1 mg/mL then decreases to 24.51 ± 11.7 μm/s in 2 mg/mL and 21.23 ± 10.5 μm/s in 3 mg/mL. …”