Dopamine D4 Receptor Activation Increases Hippocampal Gamma Oscillations by Enhancing Synchronization of Fast-Spiking Interneurons by Richard Andersson (150687)

“…Among several possible mechanisms we found that the NMDA receptor antagonist AP5 also blocks the D4R mediated increase in gamma oscillation power.…”

Impact evaluation of Zika epidemic on congenital anomalies registration in Brazil: An interrupted time series analysis by Enny S. Paixão (7419110)

“…We found that immediately after the interruption point, there was a great increase in the notification rate of congenital anomalies of 14.9/10,000 live births in the brain and eye group and of 5.2/10,000 live births in the group not related with brain or eye malformations. …”

Genome-Wide DNA Methylation Scan in Major Depressive Disorder by Sarven Sabunciyan (116846)

“…We observed decreased immunoreactivity for acetylcholinesterase in MDD brain with increased <em>PRIMA1</em> DNAm, non-significant at p = 0.08.…”

Extending the information content of the MALDI analysis of biological fluids via multi-million shot analysis by Maxim Tsypin (6841484)

“…</p><p>Results</p><p>We observed an expected decrease of noise, roughly proportional to the square root of the number of shots, over the whole investigated range of the number of shots (5 orders of magnitude), resulting in an increase in the number of reliably detected peaks. …”

The mass water content of paddy soil after harvest is strongly associated with the accumulation of organic matter as the source of available nitrogen by Hideo Azuma (12063243)

“…As there was a positive correlation between WHC and MWH, a positive correlation was also observed between AN and MWH. Additionally, we investigated year-to-year variation in MWH using topsoil samples collected before autumn tillage, for 3–5 consecutive years in 24 plots, for various soil types throughout Japan. …”

Supplementary Material for: Plasmin(ogen) Acquisition by Group A <b><i>Streptococcus</i></b> Protects against C3b-Mediated Neutrophil Killing by Ly D. (4140796)

Structural plasticity of the lamina is controlled by the parallel action of a circadian clock and a phototransduction-dependent mechanism. by Martin Barth (367106)

“…Sinusoidal-function fitting revealed a best fitting period of 23.7 h for LL (F(1,563) = 17.5, p<0.0001) and DD (F(1,515) = 5.6, p<0.05) lamina volume oscillations and 24.0 h for LD (F(1,621) = 34.2, p<0.0001). …”

Gcn4 dependent outputs can sustain high translation capacity during growth. by Rajalakshmi Srinivasan (395110)

“…Data show relative luciferase amounts, and are mean+/- SD from ≥ 3 biological replicates. *p<0.05,**p<0.01,****<0.0001 (t-test). …”

PINK1 expression alters mitochondrial function and cellular viability. by Anna Sandebring (263540)

“…The PINK1 in these cells is V5-tagged at the C-terminus, the precursor (arrow) and mature (closed arrowhead) forms of PINK1 are visible. …”

CoA administration prevents ISC dysfunction through antioxidative ability and protects ISCs from stress-induced DNA damage. by Zhiming Liu (216751)

“…Scare bar: 10μm (A, C), 5μm (E-J). Error bars indicate SDs. ROI size: 1.5x10⁴ μm². …”

Median Fluorescence Intensity (MFI) of MHC-I, before and after mechanical stress. by Rosanna La Rocca (679131)

“…<p>Panel A shows the decrease of the MHC class I molecules expression on cancer cells (5 melanoma and one lymphoblastoid cell lines) after mechanical stress treatment by means of the micropump (upper part) and the shock waves (lower part) compared with untreated cells. …”

Effect of 1,25(OH)₂D3 on the production of KIM-1 and fibronectin 1 from HRPTEpiC induced by recombinant human IL-17 (rhIL-17), human TNF- α or TGF-beta. by Byung Ha Chung (314449)

“…<p><b>(A)</b> The expression of KIM-1 by HRPTEpiC was pretreated with 1,25(OH)₂D3 (10 nM) as indicated, and then cultured for 24 hours with TNF-α (50 ng/mL) and/or IL-17 (50ng/mL) (n = 3). …”

Microscopic structure of active actin/cortexillin-I networks. by Simone Köhler (154623)

“…The apparent diffusion constant as given by the intercept decreases for clusters at late times. The histograms of cluster volumes (<b>D</b>) obtained from confocal micrographs (shown is a histogram over all times normalized to the number of clusters <i>N</i> found in a 456x456x50 m confocal volume) demonstrate, that the maximal cluster size (arrows) increases from apolar cortexillin-I active gels (red, <i>N</i> = 1366) over composites of fascin and cortexillin-I (green; 0.5 M each, <i>N</i> = 1318) to unipolar bundled actin/fascin/myosin networks (blue, 1 M fascin, <i>N</i> = 5260) by two orders of magnitudes. …”

Table_1_Novel Volumetric and Surface-Based Magnetic Resonance Indices of the Aging Brain – Does Male and Female Brain Age in the Same Way?.XLSX by Przemysław Podgórski (7325084)

“…</p><p>Results: In men and women, a decrease in GM and WM volumes and an increase in CSF volume seem to progress slowly since the age of 45. …”

Mitochondrial genome-encoded long noncoding RNA and mitochondrial stability in diabetic retinopathy by Jay Kumar (10445417)

“…Compared to NG, HG downregulated Lnc<em>CytB</em> by >50%, but had no significant effect on the other mtDNA-encoded LncRNAs. mtDNA packaging was impaired and MNase sensitivity was increased, and Lnc<em>CytB</em> occupancy at mtDNA was decreased. …”

Characterization of advanced glycation end products and their receptor (RAGE) in an animal model of myocardial infarction by Bianca de Moraes Fracasso (6199568)

“…A decrease in yellowish-brown AGEs in heart homogenate was found, which was confirmed by immunodetection of N-ε-carboxymethyl-lysine. …”

<i>T</i>. <i>marneffei</i> infection of zebrafish at 33°C. by Felix Ellett (454831)

“…In contrast to infections at 28°C (<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1007063#ppat.1007063.g001" target="_blank">Fig 1D</a>), no consistent decrease in CFU was observed at 4 dpi. Data are mean±SD of 3 independent replicates, n = 5 embryos (pooled)/timepoint/experiment. …”

Effect of CPAF treatment on ear thickness changes over an 18 day course of thrice weekly PMA applications in WT and <i>Ptafr</i>-/- mice. by Ravi P. Sahu (342322)

“…For the sake of comparison, the data for the PMA + CPAF treatment in WT mice is included. (mean and SEM; n = 4–5 mice per group). WT mice treated with PMA + CPAF exhibit a significant decrease in ear thickness measurements relative to <i>Ptafr</i>-/- mice treated with PMA + CPAF (*, <i>p</i><0.05; **, <i>p</i><0.01; ***, <i>p</i><0.001; 2-tailed <i>t</i>-test). …”

Systematic review and meta-analysis comparing Adjustable Transobturator Male System (ATOMS) and Adjustable Continence Therapy (ProACT) for male stress incontinence by Javier C. Angulo (3607919)

“…</p><p>Results</p><p>Combined data of 41 observational studies with 3059 patients showed higher dryness (68 vs. 55%; p = .01) and improvement (91 vs. 80%; p = .007) rate for ATOMS than ProACT. Mean pad-count (-4 vs. -2.5 pads/day; p = .005) and pad-test decrease (-425.7 vs. -211.4 cc; p < .0001) were also significantly lower. …”

Liver-specific RORγ deficient mice exhibit improved insulin sensitivity and reduced gluconeogenesis. by Yukimasa Takeda (564952)

“…Hepatic glycogen was measured at ZT0. Data represent mean ±SEM, * P<0.05, ** P<0.01 by ANOVA. (<b>F</b>) The expression of a series of glucose metabolic genes was analyzed in the liver collected at ZT8 or ZT20 (n = 4–5). …”