Disease progression phenotypes, clinical cohorts, and our computational framework together with the reproducibility of disease progression pattern. by Kimiyo N. Yamamoto (213724)

The experimentally reported network parameters can generate supersaturation and be adapted to enter the inhibition-stabilized state. by Pierre Ekelmans (15470955)

“…This results in a decrease in the firing rates of both populations, as predicted by the SSN (dashed lines). …”

Leaf extracts of Campomanesia xanthocarpa positively regulates atherosclerotic-related protein expression by EDUARDO B.B. CUNHA (10363794)

“…Cell viability was affected only at higher concentrations and times. We observed decreased ICAM-1 expression in cells treated with 50 μg/ml EG and CD14 expression with IFN-γ and without IFN-γ. …”

Myotonia-causing mutations and the putative binding pocket of the 9-AC inhibitor. by Kaituo Wang (6193994)

“…(a) Overall view with all known disease and selected experimental mutations. We note that mutations of 5 residues that cause recessive myotonia and inward rectification are facing the extracellular vestibule; 3 located in a row on the same face of on helix B (M128, S132, D136) and 2 being the pore-constricting residues (K231, R421). …”

TF maps and averaged profile of alpha oscillatory response. by Audrey Breton (534422)

“…<p>A) TF map depicting the color-coded mean energy (in μV²) in response to faces in the three player rank conditions (Highest, Middle and Lowest) at the electrode Pz. …”

The effect of stimulus luminance on pupil dilation. by Elena Geangu (339260)

“…Illuminance measured at the level of the eye during the presentation of each video was within a range not expected to yield significant differences in pupil size (15.0±0.5 Lux) <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0027132#pone.0027132-MacLachlan1" target="_blank">[50]</a>. …”

Deletion of <i>Foxm1</i> from macrophages induces activation of p38 MAPK pathway. by Chinmayee Goda (8694597)

“…<p><b>(A-B)</b> Interstitial and alveolar macrophages were isolated from bleomycin-treated my<i>Foxm1</i>^-/- and control lungs using FACS sorting. qRT-PCR shows decreased <i>Foxm1</i>, and <i>Dusp1</i> mRNAs and increased <i>Tnf</i>, <i>Ccl5</i>, <i>Il1β</i>, and <i>Il6</i> mRNAs in flow-sorted interstitial and alveolar macrophages from bleomycin-treated my<i>Foxm1</i>^-/- mice. …”

Factors that drive zooplankton diversity in Neo-Tropical Savannah shallow lakes by Claudia Padovesi-Fonseca (4653880)

<i>In vivo</i> mitochondrial metabolism in SOD1^−/− mice. by Michael P. Siegel (195229)

“…Data are expressed as means ± SEM with n = 4–5 per group. In C, data are normalized to control averages. …”

Flow Increase Is Decisive to Initiate Angiogenesis in Veins Exposed to Altered Hemodynamics by Volker J. Schmidt (313862)

“…On day 15, animals were sacrificed and angiogenesis was evaluated using μCT and histological analysis. Mean flow increased from 0.5 to 2.4 mL/min and was elevated throughout the cardiac cycle at day 0 in AV-loops whereas, as expected, it remained unchanged in AA-loops. …”

DataSheet1_Melatonin Maintains Anabolic-Catabolic Equilibrium and Regulates Circadian Rhythm During Osteoarthritis Development in Animal Models: A Systematic Review and Meta-analys... by Dewan Md. Sumsuzzman (11447752)

“…Compared with the control group, MT significantly decreased the levels of interleukin-1β (IL-1β; SMD = −5.45; 95% CI [−6.78, −4.12]; p < 0.00001, and histological grading scale (SMD = −3.46; 95% CI, [−5.24, −1.68]; p < 0.0001). …”

Image_1_Tremor supression following treatment with MRgFUS: skull density ratio consistency and degree of posterior dentatorubrothalamic tract lesioning predicts long-term clinical... by Kain Kyle (15350116)

“…Combined pre-treatment CRST (mean: 60.7 ± 17.3) and HTS (mean: 19.2 ± 5.7) improved by an average of 45.5 and 62.6%, respectively. …”

Image_1_Tremor suppression following treatment with MRgFUS: skull density ratio consistency and degree of posterior dentatorubrothalamic tract lesioning predicts long-term clinical... by Kain Kyle (15350116)

“…Combined pre-treatment CRST (mean: 60.7 ± 17.3) and HTS (mean: 19.2 ± 5.7) improved by an average of 45.5 and 62.6%, respectively. …”

Associations of Lifestyle Factors, Disease History and Awareness with Health-Related Quality of Life in a Thai Population by Prin Vathesatogkit (117760)

“…Diabetes and hypertension negatively influenced PCS (mean score differences −0.6 and −1.5, p<0.001 respectively) but not MCS, whereas awareness of diabetes and hypertension negatively influenced MCS (−2.9 and −1.6, p<0.005 respectively) but not PCS. …”

Whole testicular sperm reserve and testis weight in adult TRα^AMI-ARO, and percentage of proliferating SC in TRα^AMI-ARO at P3 <i>in vivo</i> and in testicular... by Betty Fumel (456185)

“…In contrast, T3 had no effect on SC proliferative index in TRα^AMI-ARO mice (<i>P</i> > 0.05, n = 5). Data are shown as mean ± SEM. Statistical analyses: two-way ANOVA followed by Bonferroni’s <i>post-hoc</i> test. …”

<b>Single-dose replicon RNA Sudan virus vaccine uniformly protects female guinea pigs from disease</b> by Andrea Marzi (758337)

“…We demonstrate 100% survival and protection with the LION-SUDV and the LION-Combination vaccines, while the LION-EBOV vaccine achieved 50% protection. Antigen-specific humoral responses correlate with decreased virus replication and survival. …”

Laboratory changes inherent to acute kidney injury induced by aminoglycosides in wistar rats by Ana Carolina Queiroz Lima (12817512)

“…<div><p>Abstract Acute kidney injury (AKI) is defined as an increase greater than 0.3 mg/L of serum creatinine within 48 hours and is a major cause of death in patients in intensive care units. …”

AMPK Activation Attenuates Albumin-induced Alterations in Renal Tubular Cells In Vitro by Allouch, Soumaya

“…Notably, metformin also prevented albumin-induced EMT; this was marked by a 50% decrease in a-SMA and a 60% increase in E-cadherin expression. …”
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Early and Late-Term Follow-Up Results of Patients Diagnosed with Aortic Aneurysm or Aortic Dissection with Aortic Regurgitation Undergoing Aortic Valve Repair or Valve-Sparing Aort... by Görkem Yiğit (10392838)

“…Freedom from reoperation in one, two, and five years were 97.9%, 93.6%, and 81%, respectively. …”

Influenza Virus Ribonucleoprotein Complexes Gain Preferential Access to Cellular Export Machinery through Chromatin Targeting by Geoffrey P. Chase (207164)

“…To characterize the composition of vRNP export complexes and their interplay with the nucleus of infected cells, we affinity-purified tagged vRNPs from biochemically fractionated infected nuclei. …”