Rescue of the skeletal phenotype in <i>Pkd1</i>-deficient mice by transfer onto <i>Kif3a</i>-deficient background. by Ni Qiu (306495)

“…Data are expressed as the mean±SD from 5 to 6 individual mice. Values sharing the same superscript are not significantly different at <i>P</i><0.05. * indicates significant difference from wild type, single heterozygous <i>Kif3a</i>^+/Δ, and compound heterozygous <i>Pkd1</i>^+/Δ;<i>Kif3a</i>^+/Δ mice at <i>p<</i>0.05.…”

Data_Sheet_2_Cardiorespiratory Alterations in a Newborn Ovine Model of Systemic Inflammation Induced by Lipopolysaccharide Injection.PDF by Stéphanie Nault (846680)

“…LPS injection decreased locomotor activity (p = 0.03) and active wakefulness (p = 0.01) compared to the CTRL. …”

Juvenile Hormone (JH) regulation of <i>Tc-torso</i> expression in <i>Tribolium</i>. by Sílvia Chafino (17458513)

“…Error bars indicate the SEM (n = 5). Asterisks indicate statistically significant differences at ***p ≤ 0.001 (t-test). …”

Data_Sheet_1_Effect of perioperative acupuncture-assisted general anesthesia on the anesthetic dosage required in adult surgical patients: a network meta-analysis of randomized con... by Meihua Qiu (1710367)

“…</p>Results<p>Seventy-six RCTs that involved 5,877 patients were included in the analysis. Compared with GA, a significant decrease in the total dose of propofol was found for manual acupuncture (MA) assisted GA (WMD = −101.26 mg, 95% CI [−172.98, −27.06]) with moderate quality, electroacupuncture (EA) assisted GA (WMD = −54.25 mg, 95% CI [−87.25, −22.37]) with moderate quality and transcutaneous electrical acupoint stimulation (TEAS) assisted GA (WMD = −39.99 mg, 95% CI [−57.96, −22.73]) with moderate quality, respectively. …”

Data_Sheet_1_Cardiorespiratory Alterations in a Newborn Ovine Model of Systemic Inflammation Induced by Lipopolysaccharide Injection.PDF by Stéphanie Nault (846680)

“…LPS injection decreased locomotor activity (p = 0.03) and active wakefulness (p = 0.01) compared to the CTRL. …”

Table_1_Fluid resuscitation strategy in patients with placenta previa accreta: a retrospective study.docx by Fan Zhou (196667)

“…Maternal SBP, DBP, and MAP started to decrease immediately after the baby was delivered and reached a relatively stable trough state at 15–30 min after delivery. …”

The mRNA and protein levels of Vasohibin-1, renal hypertrophy, creatinine clearance and urinary albumin excretion. by Norikazu Hinamoto (575811)

“…Real-time PCR and immunoblot analysis showed a substantial decrease in the VASH1 mRNA and protein expression in the kidneys in the VASH1^+/− mice compared with the wild-type mice. …”

Optogenetic manipulation of slow oscillations. by Ksenia V. Kastanenka (3692380)

“…(<b>G-H</b>) Neuronal activity driven with light activation of ChR2 in wildtype mice (n = 3–5 mice). Control corresponds to mCherry vector lacking ChR2. …”

Table 1_Pre-COVID era pediatric disease incidence in Kazakhstan: regional panel data analysis of multiple disease groups (2010–2019).xlsx by Nurlan Smagulov (21510632)

“…Other variables with variance inflation factors ≥5 were excluded to mitigate multicollinearity.</p>Results<p>Respiratory diseases showed the highest mean incidence (57,329.86 per 100,000), with significant regional variation. …”

BPLF1 deubiquitinates TOP2 and stabilizes TOP2ccs. by Jinlin Li (2267896)

“…The intensity of the trapped TOP2α and TOP2β smears decreased over time in control untreated cells due to proteasomal degradation, while the decrease was significantly reduced upon expression of BPLF1 in Dox treated cells. …”

Changes in TEER and permeability of EA.hy926 cells exposed to EVs or pellets from infected or uninfected macrophages. by Myriam Lucia Velandia-Romero (8259726)

“…From 9 to 24 h p.e, all conditions started to show an important diminish of DB concentration specially when cells were exposed to <i>EVs (+)</i> _<i>UV</i> or <i>P (+)</i> compared to <i>EVs (-)</i> or <i>P (-)</i> and the other controls. The mean and standard deviation of 3 to 5 transwell® inserts are shown per each condition. …”

Data_Sheet_1_Cardiovascular Autonomic Function Changes and Predictors During a 2-Year Physical Activity Program in Rheumatoid Arthritis: A PARA 2010 Substudy.pdf by David Hupin (8354484)

“…HRR was measured at 1, 2, 3, 4, and 5 min following peak heart rate during exercise. …”

Rob-dependent caffeine-micFp interaction underlies species-specific antibiotic antagonisms in <i>E. coli.</i> by Christoph Binsfeld (21763112)

“…Caffeine triggers expression of MicF small RNA in a Rob-dependent manner, which then binds to the 5′-UTR of <i>ompF</i> mRNA to inhibit and decrease OmpF protein levels. …”

Fetal and maternal Doppler adaptation to maternal exercise during pregnancy: a randomized controlled trial by Irene Fernández-Buhigas (14763235)

“…Fetal UA PI <i>z</i>-score decreases during pregnancy to lower levels in the exercise group compared with the control group.…”

Image_1_Fluid resuscitation strategy in patients with placenta previa accreta: a retrospective study.TIFF by Fan Zhou (196667)

“…Maternal SBP, DBP, and MAP started to decrease immediately after the baby was delivered and reached a relatively stable trough state at 15–30 min after delivery. …”

Data_Sheet_1_Cardiovascular Autonomic Function Changes and Predictors During a 2-Year Physical Activity Program in Rheumatoid Arthritis: A PARA 2010 Substudy.pdf by David Hupin (8354484)

“…HRR was measured at 1, 2, 3, 4, and 5 min following peak heart rate during exercise. …”

An activator of G protein-coupled receptor and MEK1/2-ERK1/2 signaling inhibits HIV-1 replication by altering viral RNA processing by Raymond W. Wong (8463498)

“…<div><p>The ability of HIV-1 to evolve resistance to combined antiretroviral therapies (cARTs) has stimulated research into alternative means of controlling this infection. We assayed >60 modulators of RNA alternative splicing (AS) to identify new inhibitors of HIV-1 RNA processing—a segment of the viral lifecycle not targeted by current drugs—and discovered compound N-[4-chloro-3-(trifluoromethyl)phenyl]-7-nitro-2,1,3-benzoxadiazol-4-amine (5342191) as a potent inhibitor of both wild-type (<i>Ba-L</i>, <i>NL4-3</i>, <i>LAI</i>, <i>IIIB</i>, and <i>N54</i>) and drug-resistant strains of HIV-1 (IC₅₀: ~700 nM) with no significant effect on cell viability at doses tested. 5342191 blocks expression of four essential HIV-1 structural and regulatory proteins (Gag, Env, Tat, and Rev) without affecting total protein synthesis of the cell. …”

Functional consequences of endogenous BST2 overexpression in high grade primary breast cancer cells. by Aejaz Sayeed (220486)

“…<b><i>Bottom panel</i></b> – Data plots demonstrate an increase in the number of small (4-cell) and medium (8- to 12-cell) colonies accompanied by a decrease in the number of large-sized colonies (>25-cell) in <i>BST2</i> siRNA-treated Matrigel cultures. …”

Data Sheet 1_Unveiling the anti-inflammatory potential of olive leaf phenolic extracts in diabetes-related endothelial dysfunction.docx by Ilaria Cappellacci (12997431)

“…VCAM-1 protein expression and TNFα-induced monocyte adhesion were also significantly decreased following extract treatment. Notably, Changlot Real exhibited a broader anti-inflammatory effect across both cell types, while Picual exerted a more selective effect in GD-HUVEC.…”

DataSheet_1_Stapled peptide PROTAC induced significantly greater anti-PD-L1 effects than inhibitor in human cervical cancer cells.docx by Yu-Ying Shi (15975992)

“…</p>Results<p>In cervical cancer celllines C33A and HeLa, the stapled peptide strongly downregulated PD-L1 to < 50% of baseline level at 0.1 μM. …”