Influence of <i>k</i>₁ on the homeostatic behavior of the m7 ping-pong controller when <i>E</i>₁ binds first to free enzyme <i>Ez</i>. by Qaiser Waheed (5095328)

“…(c) A decrease of <i>k</i>₆ from 5.0 to 1.0 while <i>k</i>₁ is kept at 100.0 gives a general improvement of the homeostatic performance of the ping-pong controller, except for the higher end <i>k</i>₅ range between 900–1000, where <i>A</i>_<i>ss</i> becomes constant (indicated by the red circle). …”

Altered TRPV1 staining in spinal cord dorsal horn of diabetic mice by Reddy M Pabbidi (44094)

“…Representative pictures of TRPV1 and NeuN staining from a control (a, b, c), STZ-induced diabetic hyperalgesic (d, e, f)), hypoalgesic (g, h, i), and non-diabetic TRPV1 knock-out mice (j, k, l). …”

Wet laboratory validation of in silico results. by Patrick Baum (235495)

“…IL-6 secretion was analyzed as surrogate marker for pro-inflammatory processes. A: High content screen images of HaCaT cells treated with increasing concentrations (3.2 nM – 50 µM) of Ex1 and BI5 including DMSO (negative control) or 100 µM Valinomycin and 10 µM Chloroquine (positive control) for 24 h. …”

Inter-county mobility patterns reflect social distancing and travel restrictions. by Hengfang Deng (7003667)

“…While the data only lost a small number of devices, the two measures both plummeted more than 50% within two weeks before recovering.…”

hERG Potassium Channel Blockage by Scorpion Toxin BmKKx2 Enhances Erythroid Differentiation of Human Leukemia Cells K562 by Jian Ma (170138)

“…</p> <p>Principal Findings</p><p>The hERG potassium channel blockage by a new 36-residue scorpion toxin BmKKx2, a potent hERG channel blocker with IC₅₀ of 6.7±1.7 nM, enhanced the erythroid differentiation of K562 cells. …”

Alterations of sirtuins in mitochondrial cytochrome c-oxidase deficiency by Arne Björn Potthast (4529689)

“…</p><p>Results</p><p>We observed a significant decrease in cellular levels of all three sirtuins at the activity, protein and transcriptional level (by 15% to 50%) in COX-deficient cells. …”

Waist-to-Height Ratio and Cardiovascular Risk Factors among Chinese Adults in Beijing by Li Cai (3899)

“…AUCs for the relationships between anthropometric indices and the three outcomes were larger in women than in men, and tended to decrease with age. Optimal cutoffs for WHtR were 0.51–0.53 and 0.48–0.50 in men and women, respectively. …”

Table_1_Meta-Analysis of Dyslipidemia Management for the Prevention of Ischemic Stroke Recurrence in China.DOCX by Kang-Ning Chen (9659927)

“…</p><p>Conclusions: Effective lipid-lowering therapy could decrease the blood LDL-C level, which had a protective effect against stroke recurrence. …”

Effect of MTDH gene overexpression on clinical sensitivity of doxorubicin. by Zhenchuan Song (741160)

“…<b>(</b>F, G) In the MTDH transfected group, the cell cycle measured by FCM and showed a increase in the proportion of cells in the S and G2/M phase and decrease in cells in the G0/G1 phases compared to the untransfected group. …”

datasheet1_COVID-19 Incidence in Patients With Immunomediated Inflammatory Diseases: Influence of Immunosuppressant Treatments.docx by Natalia Soldevila-Domenech (9903768)

“…Our results report a decreased incidence of COVID-19 in patients receiving specific DMARDs with different immunodepressor mechanisms with striking sex differences. …”

Data_Sheet_1_Short-term effectiveness of baricitinib in children with refractory and/or severe juvenile dermatomyositis.xlsx by Zhaoling Wang (630187)

“…</p>Results<p>The skin rash improved in 95% of patients (19/20) at week 24, with a significant decrease of skin-DAS at weeks 12 (6.0 vs. 2.0, p < 0.05] and week 24 [6.0 vs. 1.0, p < 0.05) by median statistics. …”

Table_1_Longitudinal Gut Bacterial Colonization and Its Influencing Factors of Low Birth Weight Infants During the First 3 Months of Life.DOCX by Cheng Chi (655368)

“…Alpha-diversity of both groups displayed a decreasing trend followed by slight variations. …”

Planning Study of Flattening Filter Free Beams for Volumetric Modulated Arc Therapy in Squamous Cell Carcinoma of the Scalp by Youqun Lai (674895)

“…For HFQ-VMAT-FF plans, there was a significant decrease by 12.6% in the mean dose to the brain compared with HFF-VMAT-FF. …”

Effect of light wavelength on hot spring microbial mat biodiversity by Akifumi Nishida (4807494)

“…The specific activation of <i>Thermosynechococcus</i> led to increased abundance of several other bacteria, whereas wavelengths specific to <i>Chloroflexus</i> and <i>Roseiflexus</i> induced a decrease in >50% of the community members as compared to the dark conditions. …”

Protective Effects of Carbon Monoxide-Releasing Molecule-2 on the Barrier Function of Intestinal Epithelial Cells by Xinwei Mu (611008)

“…</p><p>Results</p><p>CORM-2 significantly reduced LPS-induced secretion of TNF-α and IL-1β. The LPS-induced decrease of TER and increase of permeability to FITC-dextran were inhibited by CORM-2 in a concentration dependent manner (P<0.05). …”

FOXC1 modulates MYOC secretion through regulation of the exocytic proteins RAB3GAP1, RAB3GAP2 and SNAP25 by Alexandra Rasnitsyn (4062982)

“…FOXC1 positively regulates RAB3GAP1 and RAB3GAP2, while either increase or decrease in FOXC1 levels beyond its normal range results in decreased SNAP25. …”

An in vitro anti-inflammatory effect of Thai propolis in human dental pulp cells by Nutthapong KANTRONG (16029384)

“…Incubation with various non-toxic concentrations of the propolis extract significantly inhibited upregulated COX-2 mRNA and protein expressions upon treatment with IL-1β (p<0.05), resulting in a significant decrease in elevated PGE2 levels (p<0.05). …”

Analysis of fitness multiplexed cell lines and identification of cell line-specific fitness phenotypes. by Daniel F. Gilbert (193637)

“…Cell fitness phenotypes were selected from ranked mean values with small values indicating strong decrease in fitness. 25, 50 and 75 top-ranking fitness phenotypes were selected for both cell lines as well as for randomly generated values from all fitness indicators and the intersection (in %) of phenotypes identified in two (<b>A</b>.) and three (<b>B</b>.) channels was calculated as measure of hit confirmation. …”

Percent of CSCs in MCF-7 human breast cancer cells treated with hyperthermia and metformin. by Hyemi Lee (342537)

“…The numbers of spheres with diameter >50 µm were counted under a microscope. The combinations of heating and metformin were statistically more effective than metformin alone.…”

Ocean Acidification Affects the Phyto-Zoo Plankton Trophic Transfer Efficiency by Gemma Cripps (2615005)

“…Under the combined indirect+direct exposure, carbon trophic transfer efficiency from phytoplankton-to-zooplankton declined to < 50% of control populations, with a commensurate decrease in recruitment. …”