NFκB is necessary and sufficient to initiate pancreatic EMT. by Caitlin M. Braitsch (7010645)

“…(C, D) Anatabine also decreased mesenchymal VIM expression (asterisks). (E) The percent area covered by VIM⁺ pixels within the pancreatic epithelium (above a set threshold) was quantified in anatabine- and vehicle-treated <i>Lats1/2</i>^<i>PanKO</i> and WT explants. …”

Effects of Maternal Exposure to Ultrafine Carbon Black on Brain Perivascular Macrophages and Surrounding Astrocytes in Offspring Mice by Atsuto Onoda (550095)

“…PVM granules were found to be enlarged and the number of PAS-positive PVMs was decreased in UfCB-exposed offspring. These results suggested that in offspring, “normal” PVMs decreased in a wide area of the CNS through maternal UfCB exposure. …”

Soil Organic Carbon Project by Minglong Liu (19558708)

“…From 2000 to 2022, POC increases by 21.8% while MAOC decreases by 5.3%, leading to a net gain of 11.0% in SOC storage and a 29.1% increase in the POC/MAOC ratio. …”

Table_1_Zika virus infection triggers lipophagy by stimulating the AMPK-ULK1 signaling in human hepatoma cells.doc by Zhao-Ling Qin (14043981)

“…However, the regulatory mechanism of lipid metabolism and the role of lipophagy in Zika virus infection remain largely unknown. Here, we demonstrated that ZIKV induced lipophagy by activating unc-51-like kinase 1 (ULK1) through activation of 5’ adenosine monophosphate (AMP)-activated protein kinase (AMPK) in Huh7 cells. …”

Image_1_Migration, invasion, and metastasis are mediated by P-Rex1 in neuroblastoma.tiff by Jillian C. Jacobson (14271370)

“…Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 (P-Rex1) has been found to stimulate migration, invasion, and metastasis in several adult malignancies. …”

Interplay in the Selection of Fluoroquinolone Resistance and Bacterial Fitness by Linda L. Marcusson (261125)

“…We identified low-fitness triple-mutants where the acquisition of a fourth resistance mutation significantly increased fitness <em>in vitro</em> and <em>in vivo</em> while at the same time dramatically decreasing drug susceptibility. …”

datasheet1_Chaihu Guizhi Ganjiang Decoction Ameliorates Pancreatic Fibrosis via JNK/mTOR Signaling Pathway.zip by Lihua Cui (298054)

“…In addition, CGGD suppressed autophagy by downregulating Atg5, Beclin-1, and LC3B and facilitated phosphorylation of mTOR and JNK in pancreatic tissues and PSCs. …”

Chemical composition of Zhumeria majdae essential oil and its effects on the expression of morphine withdrawal syndrome and tolerance to the anticonvulsant effect of morphine on pe... by G. Azimi (10405530)

“…<div><p>Abstract Regarding the proven anticonvulsant effect of Zhumeria majdae essential oil (ZMEO) in previous studies we were prompted to investigate the ZMEO effects on the tolerance to the anticonvulsant effects of morphine and the morphine withdrawal syndrome. …”

Ammonium/nitrate ratio affects the growth and glucosinolates content of pakchoi by Jing Yang (13969)

“…The highest proportion of indolyl GSs and the lowest proportion of aromatic GSs were in the sole ammonium treatment. We concluded that a high ammonium level decreases the biomass but increases the GSs concentrations in pakchoi. …”

Chromium(III) substitution inhibits the Fe(II)-accelerated transformation of schwertmannite by Girish Choppala (3348881)

“…Substitution at a Cr(III):Fe(III) ratio of 0.025 decreased schwertmannite transformation (at pH 6.5) by 18–49% (depending on Fe(II) concentrations) relative to that of Cr(III)-free schwertmannite. …”

Image_1_Irbesartan Ameliorates Lipid Deposition by Enhancing Autophagy via PKC/AMPK/ULK1 Axis in Free Fatty Acid Induced Hepatocytes.TIF by Juan He (381034)

“…To determine the underlying mechanisms of its action, we established an in vitro model of NAFLD by treating human and mouse hepatocytes with free fatty acids (FFAs) and angiotensin (Ang) II. …”

Structural model of fH-fHbp complex. by Serena Giuntini (175560)

“…</b> Alanine substitutions for arginine at residue 204 (R204A) or for lysine at position 143 (K143A) decreased or eliminated JAR 1 binding. His substitution for Arg at position 204 (R204H) did not affect JAR 1 binding (See <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0034272#pone-0034272-g005" target="_blank">Figure 5</a>). …”

Supplementary Material for: Biochemical and Morphological Characterization of a Neurodevelopmental Disorder-Related Mono-ADP-Ribosylhydrolase, MACRO Domain Containing 2 by Ito H. (4132603)

“…In Western blotting, 2 MacroD2 isoforms with molecular masses of ∼70 and ∼75 kDa started to be expressed at embryonic day 16.5, reached the maximal level at postnatal day 8, and then gradually decreased through P30. …”

Coexistence of distal oligodendrogliopathy in active NMO lesions in case NMO-4 by Katsuhisa Masaki (119851)

“…Immunostaining of Nogo-A is markedly decreased and apoptotic nuclear condensation of oligodendrocytes is present (I, insert). …”

Sequencing cost calculator. by Louis Ranjard (170210)

“…Total cost increases with the number of individuals while per individual cost decreases. Line breaks correspond to the addition of a sequencing lane to achieve the requested coverage. …”

Mutual information (MI) selection of PGT-123 epitope positions. by Andrew L. Ferguson (491758)

“…<p>The redundancy spectrum produced by application of the mutual information classification algorithm to the neutralization activity of bnMAb PGT-123 against a panel of 141 HIV-1 pseudoviruses (cf. <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0080562#pone.0080562.s001" target="_blank">Table S1</a>) using an IC₅₀ cutoff of 10 µg/ml. …”

Picroside II Attenuates Airway Inflammation by Downregulating the Transcription Factor GATA3 and Th2-Related Cytokines in a Mouse Model of HDM-Induced Allergic Asthma by Jin Choi (141568)

“…Picroside II also inhibited the expression of Th2 type cytokine genes and the transcription factor GATA3 in the lung tissues of HDM-induced mice. Finally, we demonstrated that picroside II significantly decreased the expression of GATA3 and Th2 cytokines in developing Th2 cells, consistent with <i>in vivo</i> results. …”

Data_Sheet_1_Exaggerated Exercise Blood Pressure as a Marker of Baroreflex Dysfunction in Normotensive Metabolic Syndrome Patients.PDF by Akothirene C. Dutra-Marques (10944429)

“…We evaluated BRS for increases (BRS+) and decreases (BRS−) in spontaneous BP and HR fluctuations, MSNA (microneurography), BP from ambulatory blood pressure monitoring (ABPM), and auscultatory BP during CPET.…”

The freshwater red alga <i>Batrachospermum turfosum</i> (Florideophyceae) can acclimate to a wide range of light and temperature conditions by Siegfried Aigner (3923738)

“…In addition, the effects of ultraviolet radiation (UVR) on photosynthetic pigments were analysed using HPLC and spectrophotometric methods, and cellular ultrastructure was studied using transmission electron microscopy. We found that <i>B. turfosum</i> is adapted to low light, with a light compensation point (<i>I</i>_c) and a light saturation point (<i>I</i>_k) of 8.4 and 29.7 µmol photons m^–2 s^–1, respectively, but also tolerates higher PFDs of ~1000 µmol photons m^–2 s^–1, and is capable of net photosynthesis at temperatures between 5°C and 35°C. …”

DataSheet_1_Characterization of 3D heterocellular spheroids of pancreatic ductal adenocarcinoma for the study of cell interactions in the tumor immune microenvironment.docx by Giulio Giustarini (16544991)

“…Further, 4-culture tumor spheroids decreased the concentrations of T-cell chemoattracting cytokines, i.e., CCL4, CCL5, and CXCL9, when compared with the non-cancerous spheroids, revealing a critical immunosuppressive feature of the different types of cells forming the tumor spheroids. …”