Both GBP1 and GBP2 are secreted from the fat body and directly act on the brain to induce ILP2 and ILP5 secretion. by Takashi Koyama (417981)

“…<p><b>(A, B)</b> Culturing wild-type brains with conditioned media from GBP1 and GBP2 expressing cells induces low level of ILP2 (A) and ILP5 (B) accumulation in the insulin-producing cells. …”

Results of the spatial PCA and cluster-based permutation tests of ERSP at encoding. by Makenna B. McGill (15217451)

Inhibition of the histone demethylase KDM4B leads to activation of KDM1A, attenuates bacterial-induced pro-inflammatory cytokine release, and reduces osteoclastogenesis by Joy E. Kirkpatrick (5435834)

“…Our studies indicate that ML324 also inhibits KDM4B (IC50: 4.9 μM), and decreases the pro-inflammatory cytokine response to an Aa-LPS challenge in vitro. …”

Inositol 1,4,5-trisphosphate receptor type 2 is associated with the bone–vessel axis in chronic kidney disease–mineral bone disorder by Qiong Xiao (1728025)

“…With calcium deposition in the abdominal aortas of CKD–MBD rats, RNA sequencing of the aortas revealed a significant decrease in inositol 1,4,5-trisphosphate receptor type 2 (ITPR2) gene levels in CKD–MBD rats. …”

Video_5_Intravital Multiphoton Microscopy of the Ocular Surface: Alterations in Conventional Dendritic Cell Morphology and Kinetics in Dry Eye Disease.MP4 by Arsia Jamali (8484990)

Preparations of DnaK protein are pure. by Carissa Chan (18310140)

Tankyrases maintain homeostasis of intestinal epithelium by preventing cell death by Pan Ye (2902336)

“…Here, using <i>Villin-cre</i>ERT2;<i>Tnks1</i>^-/-;<i>Tnks2</i>^fl/fl (DKO) mice, we observed that loss of TNKSs causes a rapid decrease of Lgr5⁺ intestinal stem cells and magnified apoptosis in small intestinal crypts, leading to intestine degeneration and increased mouse mortality. …”

Feeding and starvation affect the proportion and cell cycle activity of Vasa2+/Piwi1+ cells. by Eudald Pascual-Carreras (12115380)

Fig 7 - by Yu Liang (75992)

Location and geomorphological features of Northeast China. by Guofang Tao (12368729)

Data_Sheet_1_Carbon 5–60 Years After Fire: Planting Trees Does Not Compensate for Losses in Dead Wood Stores.docx by Alana J. Clason (12880049)

“…Projecting growth to 100 years since fire suggests we may see increasing divergence in carbon stores in planted stands over a full fire-return interval, but these differences remain relatively small [mean (sd): 140.8 (19.6) Mg⋅ha^–1 in planted compared to 136.9 (27.5) Mg⋅ha^–1 in not-planted stands], with 1.4 Mg⋅ha^–1 year^–1 sequestered in not-planted compared to 1.5 Mg⋅ha^–1 year^–1 in planted stands. …”

Image_1.pdf by Stuart J. Grice (225342)

Standardised values of evaluation indices. by Guofang Tao (12368729)

Cost-effectiveness analysis of universal varicella vaccination in Turkey using a dynamic transmission model by Lara J. Wolfson (7224623)

“…</p><p>Results</p><p>Five years post-introduction of UVV (1D), the projected varicella incidence rate decreases from 1,674 cases pre-vaccine to 80 cases/100,000 person-years. …”

Baseline characteristics of the study population. by Haowen Wang (9294777)

“…Investigating climate factors with cancer incidence can provide valuable insights for prevention and future disease burden prediction. We conducted a population-based ecological study using data from the World Health Organization’s Cancer Incidence in Five Continents (CI5plus, 89 cancer registries from 1998 to 2012) and the Surveillance, Epidemiology, and End Results (SEER, 607 US counties from 2000 to 2018) Program. …”

Image1_Immune cell population and cytokine profiling suggest age dependent differences in the response to SARS-CoV-2 infection.pdf by Larraitz Aragon (14604653)

“…In this work, to further understand the relationship between host age-related factors, immunosenescence/exhaustion of the immune system and the response to the virus, we characterized immune cell and cytokine responses in 58 COVID-19 patients admitted to the hospital and 40 healthy controls of different age ranges. …”

Image_5_Global burden and trends of leukemia attributable to high body mass index risk in adults over the past 30 years.tif by Hang Xiao (400864)

Image_5_The Role of Cathepsin B in the Degradation of Aβ and in the Production of Aβ Peptides Starting With Ala2 in Cultured Astrocytes.TIF by Timo Jan Oberstein (5332658)

Image5_Clinical Efficacy and Safety of Different Doses of Sildenafil in the Treatment of Persistent Pulmonary Hypertension of the Newborn: A Network Meta-analysis.TIF by Linli Sun (11475766)

“…The network meta-analysis revealed that 1.5 mg/kg of sildenafil led to a significant decrease in pulmonary artery systolic pressure (PASP) compared with 0.3 and 0.6 mg/kg (p < 0.05); 1.5 mg/kg was better than 0.3, 0.5, and 1.0 mg/kg at increasing the partial pressure of oxygen (PaO₂) (p < 0.05); 1.5 mg/kg was better than 0.5, 0.6 and 1.0 mg/kg at reducing the partial pressure of carbon dioxide (PaCO₂) (p < 0.05); and 1.2 mg/kg was better than 0.3, 0.5 and 1.0 mg/kg at increasing the arterial oxygen saturation (SaO₂) (p < 0.05). …”

Data Sheet 1_Loss of Bmal1 impairs the glutamatergic light input to the SCN in mice.docx by Hüseyin Korkmaz (20793689)

“…</p>Results<p>We found that the deletion of Bmal1 affects the light-mediated behavior in mice, decreases the retinal thickness and affects the vesicular glutamate transporters (vGLUT1, 2) in the retina. …”