A-p50 affects tumor cell survival through inhibition of NF-κB-mediated transcriptional activation by Jing Mi (18654)

“…</p><p>© 2006 The Author(s)</p> () MTT assay of cell viability. Ad-A-p50-infected A549 cells show a significant decrease in cell viability (Ad-A-p50) compared to Ad-siNT-infected cells, = 3–5 per group, = 0.0001. () Hoechst 33342 staining of apoptotic nuclei. …”

GC-MS chromatogram of the ion peak area of GEO. by Haodong Bai (10646219)

“…The garlic essential oil (GEO) had the most significant allelopathic effect (EC₅₀ = 0.0126 g mL^-1). Additionally, the enzyme activities of catalase (CAT), peroxidase (POD) and superoxide dismutase (SOD) increased during the first 8 hours of treatment at a concentration of 0.1 g mL^-1 and then declined. …”

<i>Nf1</i> OPG mice exhibit decreased hole poking in response to a novel holeboard apparatus. by David F. Wozniak (78177)

“…(C) <i>Nf1</i> OPG mice also showed a trend toward decreased general ambulatory activity although this difference was also not significant (p = 0.053). …”

Decreased aqueous humor outflow rate in sGCα₁^−/− mice. A by Emmanuel S. Buys (392112)

Kat60 lacking the MIT domain or the MIT domain and linker region detectably colocalizes with only a few, if any, microtubules in cells. by Kyle D. Grode (725568)

Adaptive radiotherapy for locally advanced non-small cell lung cancer, can we predict when and for whom? by Patrick Berkovic (808056)

“…The mean V5, V20, V30 and mean lung dose increased by 0.8, 3.1, 5.2 and 3.4%, respectively. …”

Table_1_Decrease in the number of new cancer diagnoses during the first year of the COVID-19 pandemic – cohort study of 3.5 million individuals in western Poland.docx by Maciej Trojanowski (17690721)

Hyperparameter of model. by Yeongha Kim (12174924)

“…We compare the prediction error of the existing and proposed models with the COVID-19 prediction results reported from five US states: California, Texas, Florida, New York, and Illinois. …”

Grand average ABR waveforms (N = 8) prior to (black) and following (red) SS-induced tinnitus and elicited by the second 70 dB SPL noise burst (NB2) following a 50 ms silent gap. NB... by Andrea S. Lowe (693855)

DataSheet_1_microRNA-144/451 decreases dendritic cell bioactivity via targeting interferon-regulatory factor 5 to limit DSS-induced colitis.pdf by Zhijie Lin (173992)

“…Mechanistically, the miR-144 directly targets the 3`-UTR of IRF5 and represses the expression of IRF5 in DCs. …”

50% Reduction of dynein perturbs the movement of APP vesicles. by Gary J. Iacobucci (192833)

“…<p>(<b>A</b>) A representative movie montages from a single neuron is shown from a primary neuronal culture expressing APP-YFP in the context of 100% dynein (APP-YFP) or 50% dynein (APP-YFP; robl^K −/+). …”

CHIKV-CZC-LAMP detected <50 PFU CHIKV. by Kyoko Hayashida (281242)

Lipid consumption of epimastigotes supplemented with 10 or 50% FCS. by Miria G. Pereira (212119)

“…Note that in both initial culture conditions, the fluorescence decreases along time in parasites from 10% FCS or 50% FCS. …”

Image_3_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_4_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_2_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_1_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Data Sheet 1_Probiotic Limosilactobacillus reuteri KUB-AC5 decreases urothelial cell invasion and enhances macrophage killing of uropathogenic Escherichia coli in vitro study.pdf by Arishabhas Tantibhadrasapa (13929639)

“…However, the antibacterial and immune modulatory effects of AC5 on UPEC have never been explored.</p>Methods<p>Here, we investigated both the direct and indirect effects of AC5 against UPEC isolates (UTI89, CFT073, and clinical MDR UPEC AT31) in vitro. …”

Table_1_Preclinical characterization of amubarvimab and romlusevimab, a pair of non-competing neutralizing monoclonal antibody cocktail, against SARS-CoV-2.docx by Yun Ji (464484)

“…However, the continuous virus evolution requires diverse mAb options to combat variants. Here we describe two fully human mAbs, amubarvimab (BRII-196) and romlusevimab (BRII-198) that bind to non-competing epitopes on the receptor binding domain (RBD) of spike protein and effectively neutralize SARS-CoV-2 variants. …”

Table_5_NOTCH1 mutation associates with impaired immune response and decreased relapse-free survival in patients with resected T1-2N0 laryngeal cancer.docx by Xiao-yang Gong (13103400)

“…A total of 469 genomic alterations were detected in 211 distinct cancer-relevant genes, and the genes found to be mutated in more than five patients (>10%) included tumor protein p53 (TP53, 78.5%), FAT atypical cadherin 1 (FAT1, 26%), LDL receptor related protein 1B (LRP1B, 19%), cyclin dependent kinase inhibitor 2A (CDKN2A, 17%), tet methylcytosine dioxygenase 2 (TET2, 17%), notch receptor 1 (NOTCH1, 12%) and neuregulin 1 (NRG1, 12%). …”