Hypoxia Rewires Histone Methylation in Glioblastoma Cells via Enzyme Reprogramming Despite Disruption of One-Carbon Metabolism by Hui Tang (226667)

“…Despite this blockade in one-carbon metabolism, global histone methylation patterns were not uniformly suppressed. Instead, we observed site-specific changes driven by altered expression of methyltransferases and demethylases, particularly decreased KMT1F (H3K9 methylation) and KMT2B (H3K4 methylation) and increased KDM2A (H3K36 demethylation), KDM3A (H3K9 demethylation), and KMT5A/SETD8 (H4K20 monomethylation). …”

Hypoxia Rewires Histone Methylation in Glioblastoma Cells via Enzyme Reprogramming Despite Disruption of One-Carbon Metabolism by Hui Tang (226667)

“…Despite this blockade in one-carbon metabolism, global histone methylation patterns were not uniformly suppressed. Instead, we observed site-specific changes driven by altered expression of methyltransferases and demethylases, particularly decreased KMT1F (H3K9 methylation) and KMT2B (H3K4 methylation) and increased KDM2A (H3K36 demethylation), KDM3A (H3K9 demethylation), and KMT5A/SETD8 (H4K20 monomethylation). …”

Data_Sheet_1_The Efficacy and Safety of Janus Kinase Inhibitors for Patients With COVID-19: A Living Systematic Review and Meta-Analysis.pdf by Xueyang Zhang (6816896)

Dataset: Foraminiferal denitrification and deep bioirrigation influence benthic biogeochemical cycling in a seasonally hypoxic fjord by Subhadeep Rakshit (19702714)

“…These observations were used to develop and constrain a biogeochemical reaction-transport model. The model results suggest that the observed decrease in porewater concentrations of ammonium and dissolved inorganic carbon below 5 cm depth, was due to deep bioirrigation by tubeworms. …”

Supplementary Material for: Effects of Low-Volume, High-Intensity Interval Training Compared with Continuous Training on Regional and Global Body Composition in Adults with Metabol... by Aristizabal J.C. (11527624)

“…<b><i>Objective:</i></b> The aim of this study was to compare the effects of low-volume, high-intensity interval training (HIIT) or moderate-intensity continuous training (MICT) on body composition in adults with metabolic syndrome (MS). <b><i>Methods:</i></b> This is a post hoc analysis of the randomized clinical trial Intraining-MET. …”

Impact of parental separation or divorce on school performance in preterm children: A population-based study by Simon Nusinovici (491484)

“…The mean GSA score was 50.8 points. Parental separations (assessed as parents either living together or living separately) were associated with a decrease in school performance at five years of age, although this was only the case for children who exhibited difficulties at school (3.7 points, p < 0.01). …”

Longitudinal phenotypic study of late-onset retinal degeneration due to a founder variant c.562C>A p.(Pro188Thr) in the <i>C1QTNF5</i> gene by Julie De Zaeytijd (3633118)

“…</p> <p><b>Results</b>: Best-corrected visual acuity (BCVA) and visual fields were maintained up to 50 to 55 years (n = 8), with a gradual decline, but conservation of functional central vision between 55 to 65 years (n = 15), followed by a steep decrease in overall visual function beyond 65 years (n = 9). …”

Image_1_Novel Insights Into Illness Progression and Risk Profiles for Mortality in Non-survivors of COVID-19.TIF by Liang Shao (427875)

“…Five and 13 patients were hospital-acquired and community-acquired infection of SARS-CoV-2, respectively. …”

Data_Sheet_1_Novel Insights Into Illness Progression and Risk Profiles for Mortality in Non-survivors of COVID-19.docx by Liang Shao (427875)

“…Five and 13 patients were hospital-acquired and community-acquired infection of SARS-CoV-2, respectively. …”

Image_2_Novel Insights Into Illness Progression and Risk Profiles for Mortality in Non-survivors of COVID-19.TIF by Liang Shao (427875)

“…Five and 13 patients were hospital-acquired and community-acquired infection of SARS-CoV-2, respectively. …”

MVEC-EVs promoted OPC survival, proliferation, and motility in a dose-dependent manner. by Masashi Kurachi (106280)

“…(A) The proportion of pyknotic nuclei decreased at doses ≥ 50 μg/ml. …”

VCP inhibition reduces AML cell growth and survival. by Paweł P. Szczęśniak (12359841)

Insights into Transient Dynamics of Bacteria-Laden Liquid Bridges by Kush Kumar Dewangan (20909777)

Summary of the framework for the computation of the brain transition cost from EEG data. by Giacomo Barzon (19832364)

A coarse-grained sensitivity analysis of the effect of drug-induced resistance on treatment outcome. by Erin Angelini (13149930)

“…<p>The parameters given in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1010319#pcbi.1010319.s006" target="_blank">S1 Table</a> are held fixed, while the EC50 and efficacy of resistance induction are varied in the above four cases. …”

(a) Spectrum of Bogoliubov excitations (red dots) for a harmonically trapped system, calculated for <em>J_z</em> = 1.5 δ, <em>J</em> = 2 Δ⁽²⁾, ω = 2π <b>×</b>... by Sylvain Nascimbène (557334)

“…<p><strong>Figure 5.</strong> (a) Spectrum of Bogoliubov excitations (red dots) for a harmonically trapped system, calculated for <em>J_z</em> = 1.5 δ, <em>J</em> = 2 Δ⁽²⁾, ω = 2π <b>×</b> 200 Hz. …”

Effect of desilication temperature on hybrid desilication by Nian Liu (29935)

Probability of colonization of microbial taxon 1 as a function of its frequency in the pool of colonizers. by Román Zapién-Campos (9592478)

Effects of GLSF and GLS gastrointestinal juice extracts on cell viability and transformation in JB6 P+ cell line. by Ayaz Shahid (12269599)

Data_Sheet_1_Metabolomics of Cerebrospinal Fluid in Multiple Sclerosis Compared With Healthy Controls: A Pilot Study.PDF by Michal Židó (12641944)

“…Background<p>Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS) leading to the loss of myelin and axons. …”