Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

Subjects:

Inability of macrophages to respond to IL-10 results in decreased persistence of <i>B. abortus in vivo</i>. by Mariana N. Xavier (133803)

Rac1 activity rapidly decreases upon cell-cell adhesion in 3-D cell aggregates. by Khameeka N. Kitt (227731)

“…High levels of active Rac1 at 0 minutes rapidly decreased (∼66%) within 5 minutes of cell-cell adhesion, and declined to a baseline level by 30 minutes (A). …”

NatB-inactivation decreased Drk levels through its N-terminal sequences, which was regulated by the N-end rule E3 ubiquitin ligase POE/UBR4. by Zhentao Sheng (107495)

Niphatenones block N/C interaction and inhibit expression of AR regulated genes. by Carmen A. Banuelos (636867)

Cortisone (500 nM, 24 h, black) and cortisol (500 nM, 24 h, dark grey) decrease lipogenesis in differentiated Chub-S7 cells. by Laura L. Gathercole (341979)

No change in muscle size and force, but a decrease in TB mass in 1-mo Lmna^HSA-cko mice. by Lei Xiong (334812)

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

AZ2.0 by Binay Panda (768771)

“…The updated genome assembly (v2.0) yielded 3- and 3.5-fold increase in N50 and N75, <br>respectively; 2.6-fold decrease in the total number of scaffolds; 1.25-fold increase in the number of <br>valid transcriptome alignments; 13.4-fold less mis-assembly and 1.85-fold increase in the <br>percentage repeat, resulted due to removal of mis-assembly and closure of gaps fromover the earlier <br>assembly (v1.0). …”

Nucleotide sequence changes in E6, L1 (MY), and LCR regions from A1/2, D2 and D3 HPV16 variants. by Ana Alfaro (280118)

Intrathecal injection of mycolactone triggers a decrease of pro-inflammatory cytokines in spinal cord of Sham rats. by Caroline Isaac (4600654)

The long-term impact of sustained exposure-reducing interventions (represented by a decrease in density of female anophelines). by Azra C. Ghani (160248)

HAOSMCs lacking CD9 display altered actin arrangement and a decrease in active RhoA and collagen gel contraction. by Michael J. Herr (428546)

<i>Ext1</i> mutant lungs exhibit a decrease in SHH-FGF10 signaling. by Hua He (120374)

“…The staining intensity was decreased in mutant lungs, indicating a decreased <i>Gli1</i> expression. …”

The polarization of a passive straight cable due to an extracellular field is anti-symmetric and decreases with the field frequency. by Florian Aspart (3366014)

BoNT/A (3.5 U/kg) decreases orofacial formalin-induced dural extravasation. by Boris Filipović (336089)

Ab Initio Study of the Substituent Effects on the Relative Stability of the <i>E</i> and <i>Z</i> Conformers of Phenyl Esters. Stereoelectronic Effects on the Reactivity of the Car... by Helmi Neuvonen (2643793)

“…The n_O → π*_C__O electron donation has a minimum value with τ₁ = 90° and a maximum value with τ₁ = 0° (the <i>Z</i> conformer), the value with τ₁ = 180° (the <i>E</i> conformer) being between these two values, obviously due to steric hindrance. …”

Decrease in extracellular Zn²⁺ in the hippocampus by zinc chelators. by Atsushi Takeda (18203)

ACT and ISO decrease pathological changes in LPS-induced AKI mice. by Jing Lian (1671991)