Showing 421 - 440 results of 27,277 for search '(( 50 ((ms decrease) OR (a decrease)) ) OR ( 50 ((nn decrease) OR (we decrease)) ))', query time: 0.94s Refine Results
  1. 421

    Table_2_Samm50 Promotes Hypertrophy by Regulating Pink1-Dependent Mitophagy Signaling in Neonatal Cardiomyocytes.XLSX by Ran Xu (316855)

    Published 2021
    “…We first found that Samm50 is a key positive regulator of cardiac hypertrophy, for western blot and real-time quantitative PCR detection revealed Samm50 was downregulated both in pressure-overload-induced hypertrophic hearts and Ang II-induced cardiomyocyte hypertrophy. …”
  2. 422
  3. 423

    Potent Half-Sandwich Iridium(III) Anticancer Complexes Containing C<sup>∧</sup>N‑Chelated and Pyridine Ligands by Zhe Liu (77240)

    Published 2015
    “…The monodentate py ligands blocked hydrolysis; however, antiproliferative studies showed that all the Ir compounds are highly active toward A2780, A549, and MCF-7 human cancer cells. In general the introduction of an electron-donating group (e.g., Me, NMe<sub>2</sub>) at specific positions on the pyridine ring resulted in increased antiproliferative activity, whereas electron-withdrawing groups (e.g., COMe, COOMe, CONEt<sub>2</sub>) decreased anticancer activity. …”
  4. 424
  5. 425
  6. 426
  7. 427
  8. 428

    Decreased oscillatory flow decreases <i>klf2a</i> expression. by Julien Vermot (257990)

    Published 2009
    “…<p>(A) RFF is decreased by alterations in heart rate. …”
  9. 429
  10. 430
  11. 431
  12. 432

    A Novel Highly Potent Autotaxin/ENPP2 Inhibitor Produces Prolonged Decreases in Plasma Lysophosphatidic Acid Formation <i>In Vivo</i> and Regulates Urethral Tension by Hiroshi Saga (584103)

    Published 2014
    “…To date, several autotaxin/ENPP2 inhibitors have been reported; however, none were able to completely and continuously inhibit autotaxin/ENPP2 <i>in vivo</i>. In this study, we report the discovery of a highly potent autotaxin/ENPP2 inhibitor, ONO-8430506, which decreased plasma lysophosphatidic acid formation.…”
  13. 433

    GluN2A(D731N) decreases channel open probability. by Kai Gao (120150)

    Published 2017
    “…The di-heteromeric mutant (2A-D731N) and tri-heteromeric receptors with two-copies of the mutant subunit (D731N/D731N) showed a prolonged inhibition rate, reflecting a decreased channel open probability. …”
  14. 434

    Neuropathological findings in a case with Marburg’s variant of MS (case MS-6). by Katsuhisa Masaki (119851)

    Published 2013
    “…Asterisks indicate vascular lumen (R, S). Scale Bar = 1 mm(A); 500 µm (B, C); 200 µm (D–I); 50 µm (J, K); 100 µm (L, M); 10 µm (N–Q); 20 µm (R); 50 µm (S).…”
  15. 435

    Effects of High-Intensity Interval Exercise versus Moderate Continuous Exercise on Glucose Homeostasis and Hormone Response in Patients with Type 1 Diabetes Mellitus Using Novel Ul... by Othmar Moser (789838)

    Published 2015
    “…Before exercise, standardized meals were administered, and short-acting insulin dose was reduced by 25% (A), 50% (B), and 75% (C) dependent on mean exercise intensity. …”
  16. 436
  17. 437
  18. 438

    Small Molecule ErbB Inhibitors Decrease Proliferative Signaling and Promote Apoptosis in Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia by Mary E. Irwin (293687)

    Published 2013
    “…In two human Ph+ALL cell lines, inhibition of ErbB kinase activity with canertinib resulted in a dose-dependent decrease in the phosphorylation of an ErbB kinase signaling target p70S6-kinase T389 (by 60% in Z119 and 39% in Z181 cells at 3 µM). …”
  19. 439
  20. 440

    Design, Synthesis, and Biological Evaluation of [1,2,5]Oxadiazolo[3,4‑<i>b</i>]pyridin-7-ol as Mitochondrial Uncouplers for the Treatment of Obesity and Metabolic Dysfunction-Assoc... by Mary A. Foutz (20361830)

    Published 2024
    “…Utilizing an oxygen consumption rate assay as a measure of increased cellular respiration, <b>SHO1122147</b> (<b>7m</b>) displayed an EC<sub>50</sub> of 3.6 μM in L6 myoblasts. …”