Hemolysis experiment: osmotic fragility profile of naïve (A) or infected (B) RBCs of day six infected C57BL/6 (white line) or IFNγR-/- (black line) mice. by Jennifer Cnops (385275)

Effects of Tbx5 Paralogues on the Somites. by Erin A. T. Boyle Anderson (6065756)

“…Both Tbx5b-deficient and double-deficient embryos showed a significant decrease in somite size compared to wt embryos. …”

Table 1_The burden and trends of infectious diseases among children aged 14 and below in China from 1990 to 2021: a systematic analysis from the 2021 global burden of disease study... by Chun Guo Miao (21286334)

“…Acute hepatitis mortality decreased from 7,349 deaths (95% UI:5,987–9,059) to 87 (EAPC: −13.78), with a fivefold reduction in ASMR. …”

Data Sheet 1_Psychosocial and physiological health outcomes of outdoor green exercise versus indoor exercise in knee osteoarthritis patients coexisting with type 2 diabetes mellitu... by Yilin Jin (8070026)

“…Participants’ enjoyment of exercise and intention for a future exercise behavior was measured in a questionnaire using a 100mm visual analogue scale as a continuum from 0 – ‘not at all’ to 100 – ‘very much’.…”

FIGURE 4 from D-2-HG Inhibits <i>IDH1^mut</i> Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation by Sean T. Pianka (18237413)

“…<p>FTO inhibition attenuates gliomasphere growth. <b>A,</b> Increase in U87 RNA m6A content relative to control (0 µmol/L) following the application of FTO inhibitors FB23-2 (left) or MA (right) at various doses. …”

Effect of BoNT/B and TeTx on VAMP2 Immunofluorescence by Gerardo A. De Blas (262394)

“…<p>Sperm were incubated with 100 nM BoNT/B or TeTx (15 min at 37 °C) as described in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0030323#pbio-0030323-g008" target="_blank">Figure 8</a>. …”

IFT88 shRNA shortens cilia and enhances RGC degeneration following ONT. by Brian K. A. Choi (7114916)

“…(D) Representative epifluorescence micrographs of RBPMS immunolabeled RGCs in the inner eccentricity of flatmounted retinas at 7 days post-ONT, expressing control shRNA (top) or IFT88 shRNA (bottom). Scale bar = 100 μm. (E) Quantification of RGCs showing that IFT88 shRNA expression significantly decrease RGC survival at 7 days post ONT, relative to scrambled control hairpin. …”

8-Propyl-6H-[1,3]dioxolo[4,5-g]chromen-6-one: A new coumarin with monoamine oxidase B inhibitory activity and possible anti-parkinsonian effects by María del Pilar Olaya (12848792)

“…FCS303 inhibited monoamine oxidase B (MAO-B) with an IC50 of 5.46 ± 0.36 µM; however, there was no effect on monoamine oxidase A (MAO-A). The oral administration of FCS303 led to a significant reversal of hypokinesia in the reserpine model (at 24 h, doses of 100 and 200 mg/kg) and in the levodopa/carbidopa potentiation assay (at 2 and 24 h, dose of 200 mg/kg). …”

Data_Sheet_2_Long-term trends in the burden of inflammatory bowel disease in China over three decades: A joinpoint regression and age-period-cohort analysis based on GBD 2019.PDF by Yang Zhang (30734)

“…</p>Results<p>The age-standardized incidence and mortality rates in both sexes changed from 1.47 (95% CI: 1.24, 1.74) to 3.01 (95% CI: 2.59, 3.50) and from 0.86 (95% CI: 0.59, 1.16) to 0.30 (95% CI: 0.24, 0.35) per 100,000 people in China from 1990 to 2019. The age-standardized DALY rate in China decreased from 24.47 (95% CI: 17.88, 30.19) per 100,000 people in 1990 to 13.10 (95% CI: 10.29, 16.31) per 100,000 people in 2019. …”

Data_Sheet_1_Long-term trends in the burden of inflammatory bowel disease in China over three decades: A joinpoint regression and age-period-cohort analysis based on GBD 2019.PDF by Yang Zhang (30734)

“…</p>Results<p>The age-standardized incidence and mortality rates in both sexes changed from 1.47 (95% CI: 1.24, 1.74) to 3.01 (95% CI: 2.59, 3.50) and from 0.86 (95% CI: 0.59, 1.16) to 0.30 (95% CI: 0.24, 0.35) per 100,000 people in China from 1990 to 2019. The age-standardized DALY rate in China decreased from 24.47 (95% CI: 17.88, 30.19) per 100,000 people in 1990 to 13.10 (95% CI: 10.29, 16.31) per 100,000 people in 2019. …”

Data Sheet 1_Global, regional and national burden of decubitus ulcers in 204 countries and territories from 1990 to 2021: a systematic analysis based on the global burden of diseas... by Shenyue Zhang (18472266)

“…The global ASR of prevalence decreased slightly from 8.25 to 7.92 per 100,000 persons, with most cases occurring in individuals aged 60 and older. …”

Incidence of self-reported tuberculosis treatment with community-wide universal testing and treatment for HIV and tuberculosis screening in Zambia and South Africa: A planned analy... by L. Telisinghe (18706323)

“…There was also some evidence this translated to a decrease in self-reported TB incidence overall in the population. …”

Image_1_Dual-Pathway Antithrombotic Therapy in Patients With Atrial Fibrillation After Percutaneous Coronary Intervention in Stable Coronary Artery Disease: A Single-Center, Single... by Lukas Andreas Heger (7534805)

“…</p><p>Conclusion: These observational data from a single center registry show a decrease of TAT- and VKA- prescription in favor of DAT with NOAC. …”

Data_Sheet_1_Developmental Effects on Auditory Neural Oscillatory Synchronization Abnormalities in Autism Spectrum Disorder.docx by Lisa A. De Stefano (7040126)

“…Fifteen participants with ASD (3 female, aged 6–23 years) and 15 age-matched controls (4 female, aged 6–25 years) underwent dense-array EEG as they listened to a carrier tone amplitude-modulated by a sinusoid linearly increasing in frequency from 0–100 Hz over 2 s. …”

Effects of Tbx5 paralogues on vasculature. by Erin A. T. Boyle Anderson (6065756)

“…There is a decrease in size of the subintestinal vasculature in Tbx5b-deficient (e”) and double-deficient (e”’) embryos compared to either wildtype (e) or Tbx5a-deficient embryos (e’). …”

Data_Sheet_1_Non-pharmacological interventions of travel restrictions and cancelation of public events had a major reductive mortality affect during pre-vaccination coronavirus dis... by Haoyu Wen (4961833)

“…The COVID-19 mortality date (MRT) was defined as a date when daily rate of 0.02 COVID-19 deaths per 100,000 population in a country was reached, and the COVID-19 vaccination date (VRT) was defined as people vaccinated reaching 70%. …”

Table 1_The global, regional, and national burden of colorectal cancer and its attributable risk factors in 204 countries and territories, 1990-2021: a systematic analysis for the... by Shen Tian (4424170)

“…Between 1990 and 2021, the global age-standardized mortality rate (ASDR) decreased from 15.6 to 12.4 per 100,000, and the age-standardized DALY rate declined from 357.3 to 283.2 per 100,000. …”

Power analysis of the ability of <i>Q</i>₃ to detect a signature of introgression from 15,000 simulated genes (<i>σ</i>² = 1). by Mark S. Hibbins (9728113)

Control of intracellular parasite burden by IFNγ-LPS and splenic CD4⁺ T cell-mediated macrophage activation. by Audrie A. Medina-Colorado (3684934)

“…The intracellular parasite burden in CD4⁺ T cell-macrophage co-cultures was determined using relative luminescent unit values and is presented as the percent increase or decrease from the baseline (1 hr) parasite burden (100%) for each group. …”

Image2_Utilizing multimodal mass spectrometry imaging for profiling immune cell composition and N-glycosylation across colorectal carcinoma disease progression.TIFF by Lyndsay E. A. Young (6329558)

“…We detected nearly 100 N-glycan species across all samples, revealing a shift in N-glycome profiles from normal to cancerous tissues, marked by a decrease in high mannose N-glycans. …”