Image_2_Reciprocal Relationship Between HDAC2 and P-Glycoprotein/MRP-1 and Their Role in Steroid Resistance in Childhood Nephrotic Syndrome.tif by Harshit Singh (6724346)

“…Compared to baseline, TSA treatment increased mRNA levels of P-gp and MRP-1 (fold change 7.51, 7.31, ^*p < 0.0001 in SRNS) and (fold change 3.49, 3.35, ^*p < 0.0001 in SSNS), respectively. It significantly decreased the level of HDAC2 (fold change 1.50, ^*p < 0.0001 in SRNS) (fold change 2.53, ^*p < 0.0001 in SSNS) patients.…”

Image_4_Reciprocal Relationship Between HDAC2 and P-Glycoprotein/MRP-1 and Their Role in Steroid Resistance in Childhood Nephrotic Syndrome.tif by Harshit Singh (6724346)

“…Compared to baseline, TSA treatment increased mRNA levels of P-gp and MRP-1 (fold change 7.51, 7.31, ^*p < 0.0001 in SRNS) and (fold change 3.49, 3.35, ^*p < 0.0001 in SSNS), respectively. It significantly decreased the level of HDAC2 (fold change 1.50, ^*p < 0.0001 in SRNS) (fold change 2.53, ^*p < 0.0001 in SSNS) patients.…”

Image_3_Reciprocal Relationship Between HDAC2 and P-Glycoprotein/MRP-1 and Their Role in Steroid Resistance in Childhood Nephrotic Syndrome.tif by Harshit Singh (6724346)

“…Compared to baseline, TSA treatment increased mRNA levels of P-gp and MRP-1 (fold change 7.51, 7.31, ^*p < 0.0001 in SRNS) and (fold change 3.49, 3.35, ^*p < 0.0001 in SSNS), respectively. It significantly decreased the level of HDAC2 (fold change 1.50, ^*p < 0.0001 in SRNS) (fold change 2.53, ^*p < 0.0001 in SSNS) patients.…”

Image_1_Reciprocal Relationship Between HDAC2 and P-Glycoprotein/MRP-1 and Their Role in Steroid Resistance in Childhood Nephrotic Syndrome.tif by Harshit Singh (6724346)

“…Compared to baseline, TSA treatment increased mRNA levels of P-gp and MRP-1 (fold change 7.51, 7.31, ^*p < 0.0001 in SRNS) and (fold change 3.49, 3.35, ^*p < 0.0001 in SSNS), respectively. It significantly decreased the level of HDAC2 (fold change 1.50, ^*p < 0.0001 in SRNS) (fold change 2.53, ^*p < 0.0001 in SSNS) patients.…”

Datasheet1_Short-term exposure to ultrafine and fine particulate matter with multipollutant modelling on heart rate variability among seniors and children from the CorPuScula (coro... by Pascale Haddad (678636)

“…In contrast, we observed decreases of the ratio after exposure to PM_2.5 and PM₁₀. …”

Datasheet1_Short-term exposure to ultrafine and fine particulate matter with multipollutant modelling on heart rate variability among seniors and children from the CorPuScula (coro... by Pascale Haddad (678636)

“…In contrast, we observed decreases of the ratio after exposure to PM_2.5 and PM₁₀. …”

Comparison of simulated FRAP curves to experiment, using parameters from Table 1. by Hui Wang (30400)

“…<p>Curves are normalized to unity before simulated bleaching of a region near cell tips at . (A) FRAP curves as a function of decreasing active cytoplasmic actin concentration to simulate the effects of increasing doses of LatA. …”

Zebrafish Caudal Fin Angiogenesis Assay—Advanced Quantitative Assessment Including 3-Way Correlative Microscopy - Fig 4 by Ruslan Hlushchuk (56116)

“…<p><b>DAA: Assessment of the anti-angiogenic effects of PTK787 at different concentrations 50, 100, 250, 500 nM: a-c</b> Fluorescent images of regenerating caudal fins at 3 (<b>a</b>^<b>1</b><b>-c</b>^<b>1</b>), 5 (<b>a</b>^<b>2</b><b>-c</b>^<b>2</b>) and 7 dpa (<b>a</b>^<b>3</b><b>-c</b>^<b>3</b>) under 3 different conditions: vehicle control (left column), 100 nM (middle) and 500 nM PTK787 (right column). …”

Effects of naphthazarin, oxoline and menadione on <i>skn-1</i> and Nrf2 targets in <i>C. elegans</i> and HepG2 cells. by Piper R. Hunt (214052)

“…<p>(A) Structures of plumbagin, naphthazarin, oxoline and menadione. …”

4−AP does not affect closed−state inactivation in Kv2.1/Kv9.3 heterotetramers. by Jeroen I. Stas (818580)

“…(C−D) The normalized plot of induction at −45 mV (C) and recovery at −100 mV (D) of closed−state inactivation was obtained as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0141349#pone.0141349.g004" target="_blank">Fig 4</a>. …”

High-risk lipidome signatures. by Chris Lauber (206300)

“…<p>Shown are fold-changes of lipid concentrations in the individuals of the 90%–100% N + L + P + C risk score quantile relative to those of each of the other 9 quantiles for T2D (A) and CVD (B). …”

Post-synchronization of individual cells within time-lapse series (EAW282). by Andrew Robinson (19205)

“…<p>(A) Time-lapse images of individual cells post-synchronized to the point at which the intensity of UmuC-mKate2 signal reached a maximum (typically 90–150 min after treatment with 100 J/m² UV light). …”

Image_1_Protective Effects of Phyllanthus amarus Against Lipopolysaccharide-Induced Neuroinflammation and Cognitive Impairment in Rats.tif by Akilandeshwari Alagan (6794390)

“…Subchronic administration of PA extract (100, 200, and 400 mg/kg) showed no abnormalities in neurobehavior and brain histology. …”

Image_2_Protective Effects of Phyllanthus amarus Against Lipopolysaccharide-Induced Neuroinflammation and Cognitive Impairment in Rats.tif by Akilandeshwari Alagan (6794390)

“…Subchronic administration of PA extract (100, 200, and 400 mg/kg) showed no abnormalities in neurobehavior and brain histology. …”

Table 1_Global, regional, and national burden of myocarditis in children aged 0–14 years, 1990–2021: analysis for the global burden of disease study 2021.docx by Yi-Dong Zhang (20457863)

“…Over 30 years, the global incidence rate decreased from 8.27 (95% UI, 5.35–12.34) to 7.73 (95% UI, 4.99–11.55) per 100,000 population. …”

Plasma MicroRNAs as Potential Noninvasive Biomarkers for In-Stent Restenosis by Meijiao He (666387)

“…</p><p>Results</p><p>MiR-21 levels in ISR patients were significantly higher than those in non-ISR patients and healthy controls (<i>P</i><0.05), while miR-100 (<i>P</i><0.05), miR-143 (<i>P</i><0.001) and miR-145 (<i>P</i><0.0001) levels were significantly decreased in ISR patients. …”

Experimental results. by Jing Kang (251503)

“…Below: recorded membrane potential (black) filtered with a Gaussian digital filter when injected constant current (pink) is 300 pA (left) and −100pA (right). …”

Expression of ChAT in the hippocampus, thalamus, and amygdala. by Yuxin Ma (457255)

“…<p><b>A</b>) ChAT immunoreactivity was decreased in the hippocampus contralateral to ankle inflammation in Aβ group as compared with both naïve and ACSF groups with or without ankle inflammation. …”

Image_2_Oral Delivered Dexmedetomidine Promotes and Consolidates Non-rapid Eye Movement Sleep via Sleep–Wake Regulation Systems in Mice.TIF by Zhen-Xin Feng (6050156)

“…In addition, orally delivered dexmedetomidine 100 μg/kg at 2 h into the light cycle shortened the latency to NREM sleep and increased the duration of NREM sleep for 6 h, while decreased REM sleep for 6 h. …”

Image_1_Oral Delivered Dexmedetomidine Promotes and Consolidates Non-rapid Eye Movement Sleep via Sleep–Wake Regulation Systems in Mice.TIF by Zhen-Xin Feng (6050156)

“…In addition, orally delivered dexmedetomidine 100 μg/kg at 2 h into the light cycle shortened the latency to NREM sleep and increased the duration of NREM sleep for 6 h, while decreased REM sleep for 6 h. …”