Differential antibody and cytokine responses associated with resistance to <i>T. cruzi</i>. by Marianne A. Bryan (246141)

“…<p>These plots model responses in <i>T. cruzi</i> infected C57Bl/6 and Balb/c mice compared to control mice inoculated with heat-inactivated parasite (original data in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g001" target="_blank">Fig 1</a>–<a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g002" target="_blank"></a><a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g003" target="_blank"></a><a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g004" target="_blank"></a><a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0000733#pntd-0000733-g005" target="_blank">5</a>) and show the association of parasite-specific antibody responses in the blood and spleen with decreased polyclonal antibody responses and differential cytokine expression (kinetics and quality summarized here). …”

The Ipsilateral Retinogeniculate Projection Is Altered in Ten_m3 KO Mice by Catherine A Leamey (62507)

“…</p> <p>(G and H) Plots of the mean ± standard error of the mean (s.e.m.) distribution of the ipsilateral projection along the DV-ML axis in five WT (G) and five KO (H) animals. In WTs, a smooth bell-shaped curve is seen that rises to peak around 30%–40% of the DV-ML axis and decreases to low values by around 60% of the axis. …”

Long-term trends in incidence and risk factors for ischaemic stroke subtypes: Prospective population study of the South London Stroke Register by Hatem A. Wafa (5823872)

“…Between 2000–2003 and 2012–2015, the age-adjusted incidence of IS decreased by 43% from 137.3 to 78.4/100,000/year (incidence rate ratio [IRR] 0.57, 95% CI 0.5–0.64). …”

Risk of Urogenital Infections in People with Type 2 Diabetes Initiating SGLT2i versus GLP-1RA in Routine Clinical Care: A Danish Cohort Study by Christine Ljungberg (20880865)

“…</p><p><br></p><p dir="ltr">Results </p><p dir="ltr">This study included 52,414 SGLT2i initiators and 27,023 GLP-1RA initiators with a median follow-up of 2.9 to 3.9 years. The estimated risks of UTI within the first year were nearly identical: 10.0% in SGLT2is, 10.2% in GLP-1RAs in intention-to-treat analyses corresponding to a risk ratio of 0.98 (95% CI 0.94, 1.03). …”

DataSheet_1_Azacitidine and lenalidomide combination: a novel relapse prophylaxis regimen after allogeneic hematopoietic stem-cell transplantation in patients with acute myeloid le... by Yimei Feng (6383840)

“…With a median follow-up time of 608 (43-1440) days, the estimated 1-year disease free survival (DFS) was 82%, cumulative incidence of relapse (CIR) was 18%, and overall survival (OS) was 100%. …”

DataSheet1_Establishment of a human nasal epithelium model of histamine-induced inflammation to assess the activity of fexofenadine as an inverse agonist and its link to clinical b... by Anne Barbot (18810823)

“…FEX works as an inverse agonist, with a higher effect when used before+during versus only during the HIS challenge. …”

Supplementary file 1_Association between changes in corrected anion gap and mortality among critically ill patients during ICU stay: a multicenter observational study.doc by Yanli Hou (6561536)

“…ΔcAG was calculated as shown as follows: ΔcAG=|final cAG ‐ initial cAG|initial cAG×100%.</p>Results<p>Among the 11,216 enrolled patients, 4,147 (37%) individuals were classified into cohort A, while 7,069 (63%) patients were assigned to cohort B. …”

DataSheet_1_Immune-related adverse events associated with nab-paclitaxel/paclitaxel combined with immune checkpoint inhibitors: a systematic review and network meta-analysis.pdf by Wenjing Hao (529440)

“…PD-L1 resulted in a noticeably lower risk of grade 1-5 hypothyroidism (OR=0.34, 95% CrI: 0.12-1.00) than PD-L1+PTX. …”

Scribble regulates myelin thickness and ERK activation in oligodendrocytes. by Andrew A. Jarjour (343100)

“…<p>A,B,D,E; At P40, decreased myelination of small-diameter axons in both optic nerve (B) and spinal cord (E) of Scribble cKO mice persists relative to wild-type littermates (A,D). …”

Table_1_Variation in Cancer Incidence Rates Among Non-Hispanic Black Individuals Disaggregated by Nativity and Birthplace, 2005-2017: A Population-Based Cancer Registry Analysis.do... by Adana A. M. Llanos (3821455)

“…Age-adjusted cancer incidence was lower for Jamaican-born (114.6 per 100,000) and other-Caribbean-born females (128.8 per 100,000) than African-born (139.4 per 100,000) and Haitian-born females (149.9 per 100,000). …”

Table_2_Variation in Cancer Incidence Rates Among Non-Hispanic Black Individuals Disaggregated by Nativity and Birthplace, 2005-2017: A Population-Based Cancer Registry Analysis.do... by Adana A. M. Llanos (3821455)

“…Age-adjusted cancer incidence was lower for Jamaican-born (114.6 per 100,000) and other-Caribbean-born females (128.8 per 100,000) than African-born (139.4 per 100,000) and Haitian-born females (149.9 per 100,000). …”

Table1_Effectiveness and safety of tenofovir amibufenamide and its comparison with tenofovir alafenamide in patients with chronic hepatitis B: results from a retrospective real-wor... by Lanqing Li (11505488)

Datasheet1_Comparative effectiveness of standard vs. AI-assisted PET/CT reading workflow for pre-treatment lymphoma staging: a multi-institutional reader study evaluation.pdf by Russell Frood (8485714)

“…</p>Results<p>There was a significant decrease in time between non-AI and AI-assisted reads (median 15.0 vs. 13.3 min, p < 0.001). …”

Data Sheet 1_Host-specific vascular endothelial cell responses to Angiostrongylus vasorum: a comparative in vitro study in red foxes (Vulpes vulpes) and domestic dogs.docx by Belinda Eisenhut (21466943)

“…</p>Discussion<p>These findings corroborate that foxes have developed mechanisms for a regulated immune response following A. vasorum exposure, while dogs exhibit a higher pro-inflammatory reaction, contributing to severe clinical outcomes. …”

Table_1_Trends in outpatient and inpatient visits for separate ambulatory-care-sensitive conditions during the first year of the COVID-19 pandemic: a province-based study.DOCX by Tetyana Kendzerska (519437)

“…CHF-related hospitalizations also decreased, albeit to a lesser extent. For angina, hypertension, diabetes, and epilepsy, hospitalization rates reduced initially, but returned to pre-pandemic levels by the end of the year.…”

Upper panel: The minimum-norm solution for the difference between the Grand Means of the tinnitus and the control groups indicates a greater prefrontal activity (dark shading) in t... by Nathan Weisz (3118)

“…</p> The darkest shading corresponds to 100% of the maximum activation (the ligther, the stronger the decrease relative to the maximum). …”

Time-dependent effects of NE/IFN-γ on MHC-I (A), B7-1 (B), IDO (C) and B7-H1 (D) mRNA expression. by Liancai Wang (306725)

Data Sheet 1_Synergistic amelioration of renal oxidative stress, inflammation, and fibrosis by combination of metformin and Clinacanthus nutans leave extracts in a type 2 diabetic... by Pongrapee Laorodphun (21195563)

“…The diabetic rats were randomly divided into four groups: untreated diabetic rats (DM), diabetic rats treated with CN at doses of 100 or 200 mg/kg/day (DM100 or DM200), diabetic rats treated with a combination of CN and metformin (DMCOM), and diabetic rats treated with metformin at 100 mg/kg/day (DMMET). …”

Recombinant CCR5-T4L acts as a HIV-1 co-receptor and down-regulates WT-CCR5 expression on the 3T3T4 cell surface. by Qingwen Jin (767337)

“…CCR5 expression was measured using flow cytometry and a PE-conjugated monoclonal antibody (2D7). The averaged mean fluorescence values (MFVs) for CCR5 from three experiments are plotted as a bar diagram, where WT-CCR5 expression after transfection with WT-CCR5 plus empty vector is set at 100. …”

NSAIDs do not prevent the increase in [Ca²⁺]_cyt induced by Aβ_1–42- oligomers or affect cell ATP levels. by Sara Sanz-Blasco (271498)

“…<i>H</i>. Salicylate 100 µM increased [Ca²⁺]_cyt further in cells treated with Aβ_25–35 (20 µM). …”