The use of anticoagulants in patients with non-valvular atrial fibrillation between 2005 and 2014: A drug utilization study using claims data in Japan by Kiyoshi Kubota (561420)

“…</p><p>Results</p><p>From 2005 to 2014, the standardized prevalence of NVAF increased from 117/100,000 to 278/100,000 and the proportion of anticoagulant users increased from 38.4% to 58.0%, while that of antiplatelet monotherapy decreased from 32.3% to 12.0%. …”

The ATG8-interacting motif 1 (AIM1) and AIM5 in p20 are indispensable for its interaction with ATG8 and autophagy induction. by Yongle Zhang (11355546)

B cell-deficient μMT mice exhibit diminished levels of IFN-γ-producing CD4⁺ T cells during chronic TB. by Yong Chen (109188)

Lithium reduced Aβ burden and phospho-APP(Thr668) levels in 3-month-old TgCRND8 mouse brain. by Anna Fiorentini (358565)

“…(H) Quantitative analysis of protein levels showing a statistically significant decrease of p-APP(Thr668) levels in the cortex and hippocampus of lithium-treated Tg mice compared with saline-treated Tg controls. …”

Increased IL-10 production by the lung cells of B cell-deficient μMT mice during chronic infection with <i>M</i>. <i>tuberculosis</i>. by Yong Chen (109188)

IL-2 Stimulated but Not Unstimulated NK Cells Induce Selective Disappearance of Peripheral Blood Cells: Concomitant Results to a Phase I/II Study by Claudia Brehm (197437)

“…The reduction of NK cells was due to both, a decrease in patients' own CD69⁽⁻⁾ NCR^(low)CD62L⁽⁺⁾ NK cells as well as to a diminishing of the transferred cells from the NK-DLI_{(IL-2 stim)} with the CD56^(bright)CD16^(+/−)CD69⁽⁺⁾NCR^(high)CD62L⁽⁻⁾ phenotype. …”

A kinome-wide RNAi screen identifies host genes that influence <i>P. berghei</i> sporozoite infection of Huh7 cells. by Miguel Prudêncio (74730)

“…Shading and colour attributions are the same as in panel (B). with red circles representing the siRNAs targeting the 16 genes selected to undergo a third screening pass. The horizontal lines represent 100%±2.0 s.d. of the average of all the negative controls in the assay. …”

valuation of salt tolerance in selected Qatari halophytes at the two initial growth stages by Alhaddad, Fedae A.

“…In general the seed germination experiments showed a decrease in the rate of germination as the salt concentration increased. …”
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Supplementary Material for: Romiplostim Treatment in Adults with Immune Thrombocytopenia of Varying Duration and Severity by Janssens A. (4152718)

“…Romiplostim is recommended for the second- and third-line treatment of primary immune thrombocytopenia (ITP). We conducted a large, single-arm study (clinicaltrials.gov; NCT00508820) with broad entry criteria to evaluate the safety of romiplostim in adult ITP. …”

Co-application of sNPF with other <i>Drosophila</i> peptides suggests that sNPF and PDF may have a unique interaction. by Dóra Nagy (5893892)

“…(HL3) (B) Maximum inverse FRET changes quantified for each individual neuron and averaged for each treatment from 100 s until 1000 s. Statistical comparison revealed that co-application of sNPF with SDNFMRFa, AKH, and DTK resulted in a significant decrease of cAMP levels compared to the sNPF+PDF co-application. sNPF+Ast-C led to a significant increase in the level of cAMP, however similar change was observed in the case of Ast-C application alone. …”

Data_Sheet_1_Effect of garlic extract on weight loss and gut microbiota composition in obese women: A double-blind randomized controlled trial.xlsx by Fateme Ettehad-Marvasti (14000610)

“…Allium and placebo caused a 1.7% and 2.7% decrease in BMI from the baseline values, respectively (P < 0.01). …”

The CD4⁺ T cell population in the lungs of B cell-deficient mice during chronic Mtb infection. by Yong Chen (109188)

Incident Tuberculosis during Antiretroviral Therapy Contributes to Suboptimal Immune Reconstitution in a Large Urban HIV Clinic in Sub-Saharan Africa by Sabine M. Hermans (249344)

“…We sought to determine the incidence and the long-term effects of TB during ART on HIV treatment outcome, and the risk factors for incident TB during ART in a large urban HIV clinic in Uganda.…”

Mapping maternal mortality rate via spatial zero-inflated models for count data: A case study of facility-based maternal deaths from Mozambique by Osvaldo Loquiha (300896)

“…<div><p>Maternal mortality remains very high in Mozambique, with estimates from 2015 showing a maternal mortality ratio of 489 deaths per 100,000 live births, even though the rates tend to decrease since 1990. …”

rTsTryp degrading or down-regulating TJ proteins in Caco-2 cell monolayer. by Lu Lu Han (4759488)

rTsTryp mediated larval invasion of Caco-2 monolayer via binding to PAR2 and activating ERK1/2 pathway. by Lu Lu Han (4759488)

Temporal dynamics of the response of the deterrent-sensitive neuron to 10 mM concentrations of (A) IR3535, (B) picaridin, and (C) DEET. by Jillian L. Sanford (582153)

“…<p>All repellents elicited a phasic-tonic firing pattern which peaked within the first 100–200 ms following stimulus onset and gradually decreased over the next 800 ms for picaridin and 1000 ms for both DEET and IR3535. …”

IL-10R blockade reverses the inflammation and diminished CD4⁺ T cell response phenotypes observed in the lungs of B cell-depleted C57BL/6 mice during chronic <i>M</i>. <... by Yong Chen (109188)

Figure S1 - The Heart Is an Early Target of Anthrax Lethal Toxin in Mice: A Protective Role for Neuronal Nitric Oxide Synthase (nNOS) by Mahtab Moayeri (120194)

“…LT-treated groups were not statistically different from their untreated counterparts for any parameter but a decrease in EF values following toxin treatment was indicative of contractile dysfunction.…”

B cell-depleted WT C57BL/6 mice also exhibit diminished granulomatous inflammation and Th1 response and enhanced IL-10 levels in the lungs during chronic <i>M</i>. <i>tuberculosis<... by Yong Chen (109188)