Supplementary Material for: Atypical COVID-19-related Acute Macular Neuroretinopathy with Progression resulting in Severe Vision Loss by Weinberger E.M (20394746)

“…Introduction: We review the clinical course of a patient with decreased vision in the setting of COVID-19 infection consistent with an atypical presentation of acute macular neuroretinopathy (AMN). …”

Dynamics of pericytes in the HUVEC-pericyte coculture system. by Kei Sugihara (8285022)

“…Scale bars: 500 μm (a–g); 100 μm (h–k).</p>…”

Supplementary Material for: Newborn Resuscitation Training Programmes Reduce Early Neonatal Mortality by Pammi M. (4159786)

“…Decreasing trends were noted for late neonatal mortality [RR 0.47 (95% CI 0.20-1.11)] and perinatal mortality [RR 0.94 (95% CI 0.87-1.00)], but there were no differences in fresh stillbirths [RR 1.05 (95% CI 0.93-1.20)]. …”

Systemic antioxidant treatment and intermittent fasting delay axonal degeneration in mice. by Andrea Calixto (16070)

“…The neurofilament signal decrease progressively at 3, 5 and 7 days after nerve injury in non-treated mice (A). …”

PRISMA flow-chart of the study selection process. by Xiaoqi Wu (9503481)

“…Meta analysis results showed that, compared with conventional western medicine alone, STS combined with conventional western medicine could reduce the frequency (SMD = -2.61, 95%CI[-4.27, -0.96], <i>P</i> = 0.002) and duration (SMD = -4.01, 95%CI[-6.18, -1.84], <i>P</i> = 0.0003) of angina pectoris, improve ECG efficacy (OR = 3.61, 95%CI[2.79, 4.68], <i>P<</i>0.00001) and clinical symptom efficacy (OR = 4.02, 95%CI[3.32, 4.87], <i>P<</i>0.00001), reduce TG(SMD = -0.60, 95%CI[-1.04, -0.16], <i>P</i> = 0.008), TC(SMD = -3.86, 95%CI[-6.37, -1.34], <i>P</i> = 0.003), and LDL-C(SMD = -1.54, 95%CI[-2.67, -0.42], <i>P</i> = 0.007), decrease plasma viscosity(SMD = -1.02, 95%CI[-1.58, -0.47], <i>P<</i>0.0003), whole blood low shear viscosity(SMD = -0.85, 95%CI[-1.21, -0.49], <i>P<</i>0.00001), whole blood high shear viscosity(SMD = -0.82, 95%CI[-1.44, -0.20], <i>P</i> = 0.009), and erythrocyte aggregation index(SMD = -1.00, 95%CI[-1.75, -0.25], <i>P</i> = 0.009), and bring down CRP(SMD = -1.39, 95%CI[-1.91, -0.86], <i>P</i><0.00001). …”

Bias risk assessment for individual studies. by Xiaoqi Wu (9503481)

“…Meta analysis results showed that, compared with conventional western medicine alone, STS combined with conventional western medicine could reduce the frequency (SMD = -2.61, 95%CI[-4.27, -0.96], <i>P</i> = 0.002) and duration (SMD = -4.01, 95%CI[-6.18, -1.84], <i>P</i> = 0.0003) of angina pectoris, improve ECG efficacy (OR = 3.61, 95%CI[2.79, 4.68], <i>P<</i>0.00001) and clinical symptom efficacy (OR = 4.02, 95%CI[3.32, 4.87], <i>P<</i>0.00001), reduce TG(SMD = -0.60, 95%CI[-1.04, -0.16], <i>P</i> = 0.008), TC(SMD = -3.86, 95%CI[-6.37, -1.34], <i>P</i> = 0.003), and LDL-C(SMD = -1.54, 95%CI[-2.67, -0.42], <i>P</i> = 0.007), decrease plasma viscosity(SMD = -1.02, 95%CI[-1.58, -0.47], <i>P<</i>0.0003), whole blood low shear viscosity(SMD = -0.85, 95%CI[-1.21, -0.49], <i>P<</i>0.00001), whole blood high shear viscosity(SMD = -0.82, 95%CI[-1.44, -0.20], <i>P</i> = 0.009), and erythrocyte aggregation index(SMD = -1.00, 95%CI[-1.75, -0.25], <i>P</i> = 0.009), and bring down CRP(SMD = -1.39, 95%CI[-1.91, -0.86], <i>P</i><0.00001). …”

Subgroup analysis of angina pectoris attack time. by Xiaoqi Wu (9503481)

“…Meta analysis results showed that, compared with conventional western medicine alone, STS combined with conventional western medicine could reduce the frequency (SMD = -2.61, 95%CI[-4.27, -0.96], <i>P</i> = 0.002) and duration (SMD = -4.01, 95%CI[-6.18, -1.84], <i>P</i> = 0.0003) of angina pectoris, improve ECG efficacy (OR = 3.61, 95%CI[2.79, 4.68], <i>P<</i>0.00001) and clinical symptom efficacy (OR = 4.02, 95%CI[3.32, 4.87], <i>P<</i>0.00001), reduce TG(SMD = -0.60, 95%CI[-1.04, -0.16], <i>P</i> = 0.008), TC(SMD = -3.86, 95%CI[-6.37, -1.34], <i>P</i> = 0.003), and LDL-C(SMD = -1.54, 95%CI[-2.67, -0.42], <i>P</i> = 0.007), decrease plasma viscosity(SMD = -1.02, 95%CI[-1.58, -0.47], <i>P<</i>0.0003), whole blood low shear viscosity(SMD = -0.85, 95%CI[-1.21, -0.49], <i>P<</i>0.00001), whole blood high shear viscosity(SMD = -0.82, 95%CI[-1.44, -0.20], <i>P</i> = 0.009), and erythrocyte aggregation index(SMD = -1.00, 95%CI[-1.75, -0.25], <i>P</i> = 0.009), and bring down CRP(SMD = -1.39, 95%CI[-1.91, -0.86], <i>P</i><0.00001). …”

Meta-analysis off requency of angina attacks. by Xiaoqi Wu (9503481)

“…Meta analysis results showed that, compared with conventional western medicine alone, STS combined with conventional western medicine could reduce the frequency (SMD = -2.61, 95%CI[-4.27, -0.96], <i>P</i> = 0.002) and duration (SMD = -4.01, 95%CI[-6.18, -1.84], <i>P</i> = 0.0003) of angina pectoris, improve ECG efficacy (OR = 3.61, 95%CI[2.79, 4.68], <i>P<</i>0.00001) and clinical symptom efficacy (OR = 4.02, 95%CI[3.32, 4.87], <i>P<</i>0.00001), reduce TG(SMD = -0.60, 95%CI[-1.04, -0.16], <i>P</i> = 0.008), TC(SMD = -3.86, 95%CI[-6.37, -1.34], <i>P</i> = 0.003), and LDL-C(SMD = -1.54, 95%CI[-2.67, -0.42], <i>P</i> = 0.007), decrease plasma viscosity(SMD = -1.02, 95%CI[-1.58, -0.47], <i>P<</i>0.0003), whole blood low shear viscosity(SMD = -0.85, 95%CI[-1.21, -0.49], <i>P<</i>0.00001), whole blood high shear viscosity(SMD = -0.82, 95%CI[-1.44, -0.20], <i>P</i> = 0.009), and erythrocyte aggregation index(SMD = -1.00, 95%CI[-1.75, -0.25], <i>P</i> = 0.009), and bring down CRP(SMD = -1.39, 95%CI[-1.91, -0.86], <i>P</i><0.00001). …”

Meta-analysis of angina pectoris attack time. by Xiaoqi Wu (9503481)

“…Meta analysis results showed that, compared with conventional western medicine alone, STS combined with conventional western medicine could reduce the frequency (SMD = -2.61, 95%CI[-4.27, -0.96], <i>P</i> = 0.002) and duration (SMD = -4.01, 95%CI[-6.18, -1.84], <i>P</i> = 0.0003) of angina pectoris, improve ECG efficacy (OR = 3.61, 95%CI[2.79, 4.68], <i>P<</i>0.00001) and clinical symptom efficacy (OR = 4.02, 95%CI[3.32, 4.87], <i>P<</i>0.00001), reduce TG(SMD = -0.60, 95%CI[-1.04, -0.16], <i>P</i> = 0.008), TC(SMD = -3.86, 95%CI[-6.37, -1.34], <i>P</i> = 0.003), and LDL-C(SMD = -1.54, 95%CI[-2.67, -0.42], <i>P</i> = 0.007), decrease plasma viscosity(SMD = -1.02, 95%CI[-1.58, -0.47], <i>P<</i>0.0003), whole blood low shear viscosity(SMD = -0.85, 95%CI[-1.21, -0.49], <i>P<</i>0.00001), whole blood high shear viscosity(SMD = -0.82, 95%CI[-1.44, -0.20], <i>P</i> = 0.009), and erythrocyte aggregation index(SMD = -1.00, 95%CI[-1.75, -0.25], <i>P</i> = 0.009), and bring down CRP(SMD = -1.39, 95%CI[-1.91, -0.86], <i>P</i><0.00001). …”

CORM-2 and tobramycin have additive effects on PAO1 biofilm formation. by Thomas S. Murray (120398)

“…<p>A) CORM-2 (100 µM) is as effective as tobramycin (1 mg/ml) in decreasing the biomass of the bacterial biofilm after 6 hours treatment, as measured by CV staining and the combination is better than either alone. …”

Incubation of NE increased number of AP evoked by ramp current stimulation. by Chunhua Zhang (148898)

“…(C, D, E) Time to first peak (TTFP) of AP in response to 100 pA (C, *p<0.05, compared with Pre), 300 pA (D,*p <0.05, compared with Pre) and 500 pA ramp current stimulation (E, *p<0.05, compared with Pre) was significantly decreased after NE incubation.…”

Effect of TAF273 on cell cycle distribution in K-562 cells treated for 72 h. by Omar Saeed Ali Al-Salahi (506413)

“…<p>The flow cytometry analysis of PI-labeled cells indicates that treatment of K-562 cells with 25 µg/ml of TAF273 for 72 h led to increase in the G1 population from 24.34% in the control cells to 40.48% in treated cells. In mean time, the S and G2 populations decreased from 61.98% and 13.68% in the control cells to 40.48% and 6.93% in treated cells, respectively. …”

Lysosomal translocation of GAPDH-HT reflects CMA activity in HeLa cells. by Takahiro Seki (185432)

“…The percentage of GAPDH-HT dot-positive cells and the number of GADPH-HT dots per cell were significantly decreased by siRNA-mediated LAMP2A-knockdown. ** p<0.001 vs cells treated with nontargeting-siRNA (unpaired <i>t</i>-test, n = 16 in <i>B</i>, n = 57 for nontargeting-siRNA and n = 74 for LAMP2A-siRNA in <i>C</i>). …”

The effect of prevalence (i.e., the proportion of presences among all the observations) on the performance of species distribution models. by Jian Huang (7250)

C2CD3 regulates spatial organization of centriole architecture. by Eloïse Bertiaux (5309927)

“…For CEP162-positive centrioles: siCTRL = 100% ± 0, siC2CD3 = 50.83% ± 4.31. Overall CEP162 fluorescence decreased in siC2CD3 (<i>n</i> = 31, 1.47 ± 0.39 AU.) vs. siCTRL (<i>n</i> = 35, 1.68 ± 0.51 AU), unpaired <i>t</i> test *** <i>P</i> value = 0.0008. …”

The effect of species divergence time on divergence-based ascertainment bias. by Andrew D. Kern (248482)

“…The strength of a divergence-based ascertainment bias decreases as a function of species divergence time, but does very slowly such that an appreciable effect remains at species divergence times of 100.…”

Effect of mCPP on insulin secretion from pancreatic β-cells. by Qiang Zhang (45005)

“…<p>A: After treatment with 1 to 100 µmol/l mCPP for 12 h, insulin secretion from Min-6 cells under stimulus of 16.7 mM glucose decreased in a mCPP dose-dependent manner (n = 6; ^*<i>P</i><0.05; ^**<i>P</i><0.01). …”

Pharmacologic inhibition of YAP inhibits tumor growth <i>in vivo</i>. by Katherine K. Slemmons (817850)

“…<p><b>(A)</b> SMS-CTR cells treated with 10μM VP have decreased cell growth, measured by manual cell counting over five days. …”

Effect of the MRP on the accumulated number of infected nodes. by Damian Tago (2833622)

“…<p>When the disease can be transmitted only through the trade network (green line), the MRP is a very efficient tool to stop the spreading of the disease. …”

Kinetics of PI(3,4,5)P3 hydrolysis by PTEN at different concentrations of YFP-PHGrp1. by Chun Liu (47227)

“…<p>(A) The membrane composition is 0.2% PI(3,4,5)P3 + 5% DOPS + 0.2% PI(4,5)P2 + 94.4% DOPC + 0.2% TR-DHPE and the bulk concentration of YFP-PHGrp1 is 100 nM (square), 150 nM (circle), 300 nM (triangle), and 600 nM (down-pointing triangle), respectively. …”