WIKI4 inhibits the functional outcomes of Wnt/ß-catenin signaling. by Richard G. James (114424)

“…(<b>C</b>) Treatment with WIKI4 prevents the decrease in co-expression of markers of undifferentiated hESCs following Wnt3A stimulus. hESCs were stimulated with the indicated treatments and expression of GCTM2 and CD9 was assessed by flow cytometry following six days of treatment. …”

Effects of the activation and inhibition of NOTCH signalling on spinal cord progenitor cell proliferation and neuronal generation. by Barbara Hämmerle (36261)

“…Higher magnification of a single optical section (5 µm) of the boxed region of F showing two double labelled cells. …”

Proteomic Biomarkers for Ageing the Mosquito <em>Aedes aegypti</em> to Determine Risk of Pathogen Transmission by Leon E. Hugo (252728)

“…Using the 2-D Difference Gel Electrophoresis (2-D DIGE) procedure, we investigated the abundance of up to 898 proteins from the Yellow Fever and dengue virus vector, <i>Aedes aegypti</i>, during ageing. By applying a mixed-effects model of protein expression, we identified five common patterns of abundance change during ageing and demonstrated an age-related decrease in variance for four of these. …”

Significantly enriched pathways after infection by EV-D94 or EV-D68 in respiratory and intestinal tissues. by Ines Cordeiro Filipe (5849144)

“…<p><b>A)</b>. Genes with average log2 fold change increase/decrease of 0.5 versus the mock were considered for pathway analysis. …”

Solution X-ray Absorption Fine Structure Study of the Eu²⁺ and Sr²⁺ Ions:  Unexpected Solvent and Metal Ion Dependencies of the Solvation Numbers by Gilles Moreau (3042738)

“…For both Eu²⁺ and Sr²⁺ ions, a decrease in coordination number (<i>N</i>) and metal-to-solvent distances was found along the increasingly solvating MeCN < H₂O ≪ DMF < DMSO solvent series:  for strontium, <i>N</i> = 8 with [Sr(MeCN)₈]²⁺ (2.665(6) Å) and [Sr(H₂O)₈]²⁺ (2.600(3) Å) and <i>N</i> = 7 with [Sr(DMF)₇]²⁺ (2.555(5) Å) and [Sr(DMSO)₇]²⁺ (2.540(7) Å); for europium(II), <i>N</i> = 8 with [Eu(MeCN)₈]²⁺ (2.640(4) Å), <i>N</i> = 7 with [Eu(H₂O)₇]²⁺ (2.584(5) Å), and <i>N</i> = 6 with [Eu(DMF)₆]²⁺ (2.541(3) Å) and by extrapolation [Eu(DMSO)₆]²⁺ (2.525 Å). …”

Table1_The clinical and genetic aspects of six individuals with GH1 variants and isolated growth hormone deficiency type II.docx by Xiaozhen Huang (5858690)

“…Background<p>Isolated growth hormone deficiency type II (IGHD II) is an autosomal dominant disorder characterized by a GH1 gene variant resulting in a significant reduction in growth hormone (GH) secretion and a subsequent decrease of plasma insulin-like growth factor 1 (IGF-1) levels and eventual growth impairment.…”

Phospholamban Modulates the Functional Coupling between Nucleotide Domains in Ca-ATPase Oligomeric Complexes in Cardiac Sarcoplasmic Reticulum by Linda T. L. Chen (2384860)

“…Accompanying the phosphorylation of PLB, neighboring Ca-ATPase polypeptide chains exhibit a 4 ± 2 Å decrease in the proximity between FITC sites within the N-domain and a 9 ± 3 Å increase in the proximity between IAF sites within P-domains. …”

C-phycocyanin protects cells from free radical-mediated lipid peroxidation (LPO) induced by oxalate. by Shukkur M. Farooq (300564)

“…Band intensity of HEL is prominent in oxalate-alone-treated cells (G2) at 72 kDa and 50 kDa compared to control MDCK cells (G1), whereas oxalate+CP cells (G3) showed decreased HEL band intensity relative to oxalate-treated cells (G2). …”

Response to NLC for 1 122 native plant species with significant null models. by Kaixuan Pan (11714457)

“…All mean values are means ± SE.</p>…”

Validation of E. coli Signaling Network Model by Burton W Andrews (274358)

“…</p><p>(B) Response to a positive (+0.2 mM) chemoattractant impulse of width 0.5 s is also consistent with experimentally observed behavior [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0020154#pcbi-0020154-b020" target="_blank">20</a>,<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0020154#pcbi-0020154-b027" target="_blank">27</a>] (red dots show data from <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0020154#pcbi-0020154-g001" target="_blank">Figure 1</a> of [<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0020154#pcbi-0020154-b027" target="_blank">27</a>]).…”

Image_1_Chemerin and PEDF Are Metaflammation-Related Biomarkers of Disease Activity and Obesity in Rheumatoid Arthritis.pdf by Barbara Tolusso (146649)

“…Moreover, after low-calories diet, RA with low-moderate disease activity reaching BMI reduction ≥5% (62.6%) at 6 months had significant decrease of PEDF (p < 0.05) and Chemerin (p < 0.05) plasma values, in parallel with the improvement in disease activity.…”

Table1_Effects of shading on morphology, photosynthesis characteristics, and yield of different shade-tolerant peanut varieties at the flowering stage.docx by Jing Wang (6206297)

“…Shade stress led to decreased dry-matter accumulation, reduced weight of 100 fruits and kernels, and a significant decline in yield in the shade-sensitive cultivars. …”

Minimally Invasive Cardiac Surgery versus Sternotomy - Pain Investigation by Juliana Fernandes Silva (7292450)

“…In addition, patients subjected to MI procedure had a significant decrease in pain intensity from the third to the seventh PO days (p = 0.001). …”

DataSheet1_The interplay of common genetic variants NRG1 rs2439302 and RET rs2435357 increases the risk of developing Hirschsprung’s disease.PDF by Shuiqing Chi (10298891)

“…NRG1 and RET double mutants caused the most severe reduction in enteric neuron numbers than NRG1 single mutant or RET single mutant in the hindgut of zebrafish. SHSY-5Y cells and IPSCs with rs2439302 GG/rs2435357 TT genotype exhibited a decreased proliferative, migration, and differentiative capacity. …”

Table_1_Chemerin and PEDF Are Metaflammation-Related Biomarkers of Disease Activity and Obesity in Rheumatoid Arthritis.doc by Barbara Tolusso (146649)

“…Moreover, after low-calories diet, RA with low-moderate disease activity reaching BMI reduction ≥5% (62.6%) at 6 months had significant decrease of PEDF (p < 0.05) and Chemerin (p < 0.05) plasma values, in parallel with the improvement in disease activity.…”

Prospective Study of the Quality of Colonoscopies Performed by Primary Care Physicians: The Alberta Primary Care Endoscopy (APC-Endo) Study by Michael R. Kolber (428008)

“…Patient satisfaction was captured by a telephone survey.</p><p>Setting</p><p>Thirteen rural and suburban hospitals in Alberta, Canada.…”

Data_Sheet_1_From acidophilic to ornithogenic: microbial community dynamics in moss banks altered by gentoo penguins.pdf by Yevheniia Prekrasna-Kviatkovska (18117865)

“…The contrasting composition of peat and penguin feces led to the elimination of the initial peat microbiota, with an increase in Betaproteobacteria (from 1.3 ± 0.8% to 30.5 ± 23%) and Bacteroidota (from 5.5 ± 3.7% to 19.0 ± 3.7%) proportional to the intensity of penguins’ impact, accompanied by a decrease in community diversity. …”

Image_2_Chemerin and PEDF Are Metaflammation-Related Biomarkers of Disease Activity and Obesity in Rheumatoid Arthritis.pdf by Barbara Tolusso (146649)

“…Moreover, after low-calories diet, RA with low-moderate disease activity reaching BMI reduction ≥5% (62.6%) at 6 months had significant decrease of PEDF (p < 0.05) and Chemerin (p < 0.05) plasma values, in parallel with the improvement in disease activity.…”

Minimally Invasive Cardiac Surgery versus Sternotomy - Pain Investigation by Juliana Fernandes Silva (7292450)

“…In addition, patients subjected to MI procedure had a significant decrease in pain intensity from the third to the seventh PO days (p = 0.001). …”

Circular_0086414 induces SPARC like 1 (<i>SPARCL1</i>) production to inhibit esophageal cancer cell proliferation, invasion and glycolysis and induce cell apoptosis by sponging miR... by Qingfeng Jiang (9134096)

“…EC patients with low circ_0086414 expression had a poor prognosis. Increasing circ_0086414 expression led to decreased EC cell proliferation, invasion and glycolysis and increased cell apoptosis, accompanied by a decrease of N-cadherin expression and an increase of E-cadherin expression. …”