Loss of <i>Smad4</i> led to excessive proliferation of the retina cells at early development and abundant apoptosis later as assessed by pulse BrDU labeling and staining as well as... by Jing Li (10611)

“…<p><b>(A-D)</b> Results of BrDU labeling followed by immunostaining were shown in <i>Smad4</i>-cKO mice and control mice at the nasal paracentral zone of P0 and P5. …”

Longitudinal course of circulating donor-specific T-cell precursor frequencies in LTx-recipients. by Özlem Tapirdamaz (358220)

“…Donor-derived and 3^rd party-derived stimulator cells differed on the average at 1.8 HLA-AB loci and 1.5 HLA-DR loci. A. Numbers of T-cell precursors responding to donor-derived CD40-B cells increased significantly 1 week after transplantation in all T-cell subsets, followed by a decrease to values below pre-transplant levels. …”

Dose-response effects for 30 minutes luminal histamine treatment. by Qianru Zhang (292683)

Tn-seq screen for new sporulation genes. by Alexander J. Meeske (843722)

“…<b>(C)</b> Scatterplot showing the extent of decrease in transposon insertions in all genes at T5. …”

X-ChIP based affinity purification provides the most inclusive analysis of nucleoid associated proteins. by Nina Rajala (693865)

“…Samples were analysed (in duplicate for TwinkleFLAG + XL, otherwise in triplicate) by shotgun mass spectrometry using a Q Exactive Orbitrap. To again identify potentially interesting proteins we compared all 4 generated lists simultaneously using Venny, similar as in Figs. …”

Selective inhibition of EBV-positive cells to PLOD1 depletion or inhibition by 2-DP. by Jayaraju Dheekollu (56109)

“…<p><b>A)</b> Flow cytometry analysis of cell viability using propidium iodide (PI, y-axis) and Annexin V (x-axis) for DG75, BJAB, MutuI, Raji, B95.8LCL transduced with control shRNA or PLOD1 shRNA for 5 days. …”

Effect of stimulus discontinuity in the model. by Vinay Shirhatti (12872281)

“…<p>(A) Left to right: E and I response, peak power in the gamma range and the corresponding peak frequency, for different values if <i>iE</i> and <i>iI</i> for the default model weights. …”

Influence of population and exercise protocol characteristics on hemodynamic determinants of post-aerobic exercise hypotension by L.C. Brito (6936437)

“…Data analysis showed that 1) most postexercise hypotension cases are due to a reduction in systemic vascular resistance; 2) age, body mass index, and blood pressure status influence postexercise hemodynamics, favoring cardiac output decrease in elderly, overweight, and hypertensive subjects; 3) gender and training status do not have an isolated influence; 4) exercise duration, intensity, and mode also do not affect postexercise hemodynamics; 5) time of day might have an influence, but more data are needed; and 6) recovery in the supine position facilitates systemic vascular resistance decrease. …”

image_1.jpeg by Monique Mendelson (4873582)

“…For exercise training, six randomized trials were included. There was a significant decrease in apnea–hypopnea-index following exercise training (mean decrease of 8.9 events/h; 95% CI: −13.4 to −4.3; p < 0.01), which was accompanied by a reduction in subjective sleepiness, an increase in VO2peak and no change in BMI. …”

The significance of ANXA4-induced gene expression was analyzed using the Ingenuity Pathway Analysis (IPA) database. by Li-Ling Lin (137084)

“…<p>(A) 25 of the 42 candidate genes showed a significant difference in expression (a fold increase of ≥2 or a fold decrease of ≤0.5, <i>P</i><0.05) and were categorized among the three top-ranked networks. …”

Mean number of high-risk/high-return choices across trials along with standard deviations. by Yuji Takano (252785)

“…<p>A total of 100 trials were divided into 5 blocks of 20 trials. …”

Supplementary Material for: Divergence and Convergence: How Do Income Inequalities in Mortality Change over the Life Course? by Rehnberg J. (6198179)

“…<b><i>Methods:</i></b> We used Swedish total population data with 5,011,414 individual observations. …”

Phenotypes associated with lifespan extension and stress resistance are observed in <i>hyl-1;lagr-1</i>. by Mai-Britt Mosbech (435186)

“…Compared to N2 displaying a mean pumping rate of 201±2 pumps/min, <i>hyl-1;lagr-1</i> shows a 17.4% decrease with a mean pumping rate of 166±2, P<0.0001, while <i>eat-2</i> shows a 67.2% decrease with a mean pumping rate of 66±3, P<0.0001. …”

Supplementary Material for: Nintedanib in IPF: Post hoc Analysis of the Italian FIBRONET Observational Study by Harari S. (11300316)

“…The proportion of patients with cough decreased from 50.0% to 21.2% over 12 months. Two patients experienced exacerbations, 2 patients discontinued treatment, and 27 (51.9%) reported AEs. …”

<i>Pocillopora</i> spp. corallum and corallite Random Forest model and Principal component analysis. by Guinther Mitushasi (21567784)

“…Confidence of prediction is represented in A as alpha gradient (0–1). (C) <i>Pocillopora</i> corallum and corallite model’s variables of importance; mean decrease accuracy and mean decrease Gini are shown as black and white squares, respectively. …”

Efficacy of HepG2-Fluidised-bed bioreactor treatment in pigs with ischaemic acute liver failure: biochemical response. by Clare Selden (453350)

“…Concomitant with a decrease in ICP in Group 1, ammonia levels decreased (cell BAL) cf. group 2 (Control empty bead BAL); Group 1 n = 6, mean 120±8; Group 2 n = 7, mean 150±11. …”

Table_2_Potentially differential impacts on niche overlap between Chinese endangered Zelkova schneideriana and its associated tree species under climate change.docx by Yanrong Zhou (4841061)

“…The most important factor influencing its population distribution was Min temperature of coldest month (Bio6), followed by Mean diurnal range (Bio2), with the total contribution of 78.9%. (2) Currently, the suitable area of Z. schneideriana was predicted to be 106.50 × 10⁴ km², mostly located in the subtropical region of China, especially in Anhui, Hubei, Hunan, Jiangsu, and Zhejiang provinces. (3) Its suitable area would decrease and its average migration distance was 19.72 km under 16 future climate scenarios, with the core distribution migrating northeast. (4) There is an asynchrony of potential niche overlap between species pairs. …”

Comparison of autonomic stress reactivity in young healthy versus aging subjects with heart disease by Nil Z. Gurel (6681047)

“…</p><p>Results</p><p>Mental stress reduced PEP in both groups (p<0.01), although the decrease was 50% greater in the healthy group. Mean HF HRV decreased significantly in the aging group only (p = 0.01).…”

Peripheral Nerve Diffusion Tensor Imaging: Assessment of Axon and Myelin Sheath Integrity by A. Heckel (761664)

“…AD correlated with CMAP (r=0.50, p=0.04, Bonf. corr.) but not with markers of myelin sheath integrity. …”

hERG Potassium Channel Blockage by Scorpion Toxin BmKKx2 Enhances Erythroid Differentiation of Human Leukemia Cells K562 by Jian Ma (170138)

“…</p> <p>Principal Findings</p><p>The hERG potassium channel blockage by a new 36-residue scorpion toxin BmKKx2, a potent hERG channel blocker with IC₅₀ of 6.7±1.7 nM, enhanced the erythroid differentiation of K562 cells. …”