LC treatment selectively induces expression of p21^cip1 gene, mRNA and protein in cancer cells. by Hongbiao Huang (292949)

“…HepG2 cells were treated with LC (2.5, 5.0, 10 mM) for 24 h; cells were collected for gene expression profile analysis. …”

Image2_Deciphering the Active Compounds and Mechanisms of HSBDF for Treating ALI via Integrating Chemical Bioinformatics Analysis.TIF by Yanru Wang (187231)

“…<p>The Huashi Baidu Formula (HSBDF), a key Chinese medical drug, has a remarkable clinical efficacy in treating acute lung injury (ALI), and it has been officially approved by the National Medical Products Administration of China for drug clinical trials. …”

Image1_Deciphering the Active Compounds and Mechanisms of HSBDF for Treating ALI via Integrating Chemical Bioinformatics Analysis.TIF by Yanru Wang (187231)

“…<p>The Huashi Baidu Formula (HSBDF), a key Chinese medical drug, has a remarkable clinical efficacy in treating acute lung injury (ALI), and it has been officially approved by the National Medical Products Administration of China for drug clinical trials. …”

Inflammatory monocytes (IMs) are directly infected with <i>S</i>. Typhimurium and can present to antigen-specific CD4⁺ T cells. by Nancy Wang (770979)

“…IFN-γ production by CD4+ T cells was measured using intracellular staining following a 18hr stimulation period. H) CD4⁺ T cells were re-stimulated by APC subsets at 1:1 ratio, with (+) or without (-) the addition of a 5-peptide mix (FliC_429-443, GroEL_40-53, LpdA_338-351, SseI_268-280 and SseJ_329-341) that represent known CD4⁺ T cell epitopes in murine salmonellosis [<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1011666#ppat.1011666.ref020" target="_blank">20</a>,<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1011666#ppat.1011666.ref051" target="_blank">51</a>,<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1011666#ppat.1011666.ref055" target="_blank">55</a>,<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1011666#ppat.1011666.ref082" target="_blank">82</a>]. …”

The effect of temperature and acidic pH stress on the <i>de novo</i> protein synthesis in <i>Leishmania</i>. by Serge Cloutier (160605)

“…<p>(A) Levels of [³⁵S]-methionine incorporation (as an indicative of general translation rates) in <i>L. infantum</i> promastigotes subjected from 1 to 8 hours to either an elevated temperature (37°C) stress (A) or to a combined temperature and low pH (pH 5.5) stress (C). …”

The deamidation of N15 does not depend on deamidation of N71. by Ignacio de la Mora-de la Mora (435666)

“…<p>Native gel electrophoresis of the WT (A) or the N71D mutant (B) after incubation at 1mg/mL in TE buffer at 37°C with 3.5 mM GAP in a temporal course of 5 hours. …”

Hyperglycaemia-induced post-translational regulation of VEGF. by Michela M. Taiana (636319)

“…<p>(A) Exposure to glucose 45 mM for 24 hours increased the level of secreted VEGF in neuron-SC co-cultures and SC monocultures. …”

The morphogenesis and development of VM dopaminergic neurons is disturbed in <i>Dkk1^{<b>−/−</b>}</i> embryos. by Diogo Ribeiro (230483)

“…<p>(A) <i>Dkk1^−/−</i> embryos at E17.5 revealed an absence of most facial and head structures. …”

Demographic and mutation parameters estimated using approximate Bayesian computation for model <i>c</i>. by Amandine Cornille (165965)

“…<p>Posterior distributions are summarized as the mode and boundaries of the 95% credibility intervals (CI2.5 and CI97.5). Demographic parameters are introduced in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1002703#pgen-1002703-g004" target="_blank">Figure 4</a> (note that admixture times are fixed in these analyses). …”

Representative micrographs of the healing MCL after PBS or IL-1Ra treatment. by Connie S. Chamberlain (440242)

“…In contrast, proliferating cells decrease on day 5 (g–h) after IL-1Ra administration.…”

Plots illustrating different log₁₀ response patterns. by Bertrand Collet (485023)

“…(B) Sustained increase for the immunological molecule Mx. (C) Temporary decrease for the stress molecule hsp90a. Dots (·) represent unchallenged control group values and the dashed lines (---) are the predicted 2.5 and 97.5 percentiles around these. …”

Expression profiles of osmotic signaling related genes. by Lin Zhang (8926)

“…<p>This figure was modified from transcriptional regulatory networks of abiotic stress signals and gene expression <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0097878#pone.0097878-Shinozaki1" target="_blank">[32]</a>. …”

The interplay of gravity and touch responses. by Ilya Loshchilov (3992330)

“…<p>The sensitivity to gravitropic (<i>w</i>_<i>g</i>) and thigmotropic (<i>w</i>_<i>t</i>) signals was set at (a) 0.5 and 0.5, (b) 0.1 and 0.9, and (c) 0.9 and 0.1, respectively. …”

DNA microarray analysis of clinostat-induced gene expression in <i>E. coli.</i> by Kotakonda Arunasri (385358)

“…The x-axis represents the fold change and the dark vertical lines represent cut-offs at 1.5 fold decrease and increase. The y-axis represents the p-values and the dark horizontal line indicates a p value cut-off of 0.05.…”

Longitudinal evaluation of cell viability by <i>in vivo</i> BLI. by Annette Tennstaedt (834294)

“…<p>(A) BL images of unlabeled (left) and labeled (right) hNSCs, implanted in the right striatum and longitudinally evaluated from day 0 to day 9 post implantation [¹⁹F labeled cells day 0 (n = 9), day 1 (n = 9), day 2 (n = 8), day 5 (n = 8), day 7 (n = 7), day 9 (n = 5) / unlabeled cells day 0–9 (n = 4)]. …”

Identifying optimal cluster numbers in hierarchical cluster analysis. by Dolores Bernenko (16528426)

“…<p>(a) Reverse-ordered linkage values on a logarithmic scale. …”

Experiment 4. by Jiehui Qian (294581)

“…<p>a) Two lines flickered at 4 Hz during the 30-s adaptation phase; two bars were shown during the afterimage phase. b) Left: the dark red bar indicates the mean illusory decrease of the lower bar length in Experiment 4, 4.23%. …”

Roscovitine inhibition of MARCKS phosphorylation at S25 in different functional states of retinal cells. by Andrea Toledo (407433)

“…Statistical significance was determined using the nonparametric tests Kruskal-Wallis and Wilcoxon-Man Whitney. (<b>A</b>) E8 chick retina cells were cultured for 3 or 5 hours and treated during this period with 25 µM roscovitine. …”

Plasma and hepatic reaction to acute estrogen exposure. by Clémentine Chalmey (5657233)

“…*p<0.05 (two-way ANOVA, followed by Tukey test). <b>a</b> shows an increase from PND0, <b>b</b> shows a decrease from PND1, <b>c</b> shows a decrease from PND3 and <b>*</b> shows a difference from the age-matched control group.…”

Data_Sheet_1_Interplay Between Nanoplastics and the Immune System of the Mediterranean Sea Urchin Paracentrotus lividus.pdf by Carola Murano (10302947)

“…Upon transfer to PS NP-free CF, a significant decrease in fluorescence signal is observed, suggesting a fast cell clearance. …”