miR-9 attenuated the growth and metastasis of gastric cancer cells <i>in vivo</i>. by Liduan Zheng (182440)

“…<p><b>A</b> and <b>B</b>, hypodermic injection of SGC-7901 or AGS cells stably transfected with miR-9 precursor into athymic nude mice (n = 5) resulted in decreased size and weight of subcutaneous xenograft tumors than those transfected with negative control vector (mock, n = 5). …”

Knockdown and mortality rates of susceptible <i>Anopheles gambiae</i> s.s. post contact with Alpha-cypermethrin long lasting washed nets. by Josiane Etang (32709)

“…<p>A: Nets used and washed in community; B: Nets washed in laboratory conditions, M0, M1, M2, M3, M4, M5: month 0, month 1, month 2, month 3, month 4, month 5; KD60: knockdown rate of mosquitoes 60 minutes post contact to treated material; washed CM: nets washed in the community; washed Lb: nets washed in the laboratory. …”

Astroglial differentiation in hNSCs treated with STAT3 inhibitors. by Rajalaxmi Natarajan (580441)

“…(<b>D</b>) Quantitative analyses show that 0.5 µM Stattic and 0.25 µM Niclosamide significantly decrease the percentage of GFAP⁺ cells. …”

The effects of p17 are mediated by ROCK-induced activation of PTEN. by Cinzia Giagulli (354803)

“…Western blot analysis of Raji lysates shows that Y-27632 completely abrogates p17-induced decrease of both Ser/Thr pPTEN (A) and pAkt (B), as verified by densitometric analysis and plotting of pPTEN/ERK1/2 and pAkt/ERK1/2. …”

The effect of the PI3K inhibitor LY294002 (LY) on the cell viability and the [Ca²⁺]_i of primary cultured SD rat retinal cells in H₂O₂ in... by Yan Feng (128912)

“…<p>A: Western blot results of the activation of the PI3K/Akt pathway after βE2 treatment for 0.5 hrs; B: Quantitative data of A; C, E, G, and I: Cell viability quantitative data; D, F, H, and J: [Ca²⁺]_i quantitative data; C and D: The effects of LY treatments for 24 hrs and 0.5 hrs on the cell viability and the resting [Ca²⁺]_i; E and F: The inhibitory effect of LY pretreatment for 0.5 hrs on the increased cell viability and [Ca²⁺]_i induced by 10 μM βE2 treatment for 0.5 hrs (10 μM LY in E, 10 μM and 20 μM LY in F); G and H: The effect of LY pretreatment for 0.5 hrs on the decreased cell viability and increased [Ca²⁺]_i induced by 100 μM H₂O₂ treatment for 2 hrs (10 μM LY in G, 10 μM and 20 μM LY in H); I and J: The dose-dependent attenuating impact of 20-50 μM LY pretreatment for 0.5 hrs on the βE2 retinal protective role against H₂O₂ injury, which is associated with the dose-dependent attenuation of the increased [Ca²⁺]_i (Protocol of drug application: LY for 0.5 hrs, E2 for 0.5 hrs and H₂O₂ for 2 hrs). …”

Table_1_Gold complex compounds that inhibit drug-resistant Staphylococcus aureus by targeting thioredoxin reductase.pdf by Nagendran Tharmalingam (6408629)

“…In an S. aureus enzymatic assay, AU1 inhibited TrxR enzymatic activity in a dose-dependent manner causing a decrease in intracellular free thiols. …”

DataSheet_1_Gold complex compounds that inhibit drug-resistant Staphylococcus aureus by targeting thioredoxin reductase.pdf by Nagendran Tharmalingam (6408629)

“…In an S. aureus enzymatic assay, AU1 inhibited TrxR enzymatic activity in a dose-dependent manner causing a decrease in intracellular free thiols. …”

Data_Sheet_1_The combined influence of rootstock and vintage climate on the grape and wine flavonoids of Vitis vinifera L. cv. Cabernet Sauvignon in eastern China.xlsx by Xiao Han (102316)

“…The results showed that 1103P increased the pruning weight of CS and decreased the anthocyanin concentration in berries and wines, especially in the vintages with more rainy and cloudy days. 5A tended to decrease the pruning weight of CS and increase the anthocyanin concentration in berries and wines. …”

Diversification of traditional paddy field impacts target species in weed seedbank by Rubia Dominschek (12805862)

“…The seedbank was assessed in the fourth experimental year, Oct-2016, at three soil depths (0-5; 5-10 and 10-20 cm). In a mid-term temporal scale, the diversification of paddy field through ICLS did not affect weed seedbank size. …”

Changes of transcripts for GA metabolism at 6 h after gravistimulation. by Liwei Hu (454586)

“…<p>A. MapMan output was used to illustrate the significant transcriptional changes across the tissue in GA metabolism at 6 h after reorientation. …”

Comparison of characteristic properties of photocurrent signals. by Sven Geibel (453115)

“…<p>Photocurrents in response to continuous green light are characterized by five parameters: the amplitude of the transient current peak at the beginning of illumination (a), a stationary current amplitude (b), an initial amplitude of the slow phase of current decay after the end of illumination (c), a relaxation time τ₁ for the decrease from the initial peak current to the stationary level and τ₃ for the slow current decay after the end of illumination. …”

Development, optimization, and characterization of microbially triggered <i>Mimosa pudica</i> gum–chitosan polyelectrolyte complex for colon-targeted drug delivery by Samridhi Kurl (21426143)

“…A species distribution profile was constructed using the pKa values of both polymers, and polyelectrolyte complexes (PECs) were prepared at a pH value of 5.25 ± 0.10. …”

Role of the Apoptosome in Snap-Action C3 Activation by John G Albeck (268792)

“…Orange dotted line indicates the region where [XIAP]₀ = [Smac]₀ + [apoptosome]₀; numbered circles and cyan arrows indicate the positions of the indicated conditions. Point 1a corresponds to the baseline model, in which either Smac or Apaf-1 knockdown leads to a decrease in <i>f</i>, while point 1b corresponds to the baseline model with 5-fold higher Smac, in which Apaf-1 depletion does not reduce <i>f</i>.…”

Spatial mapping of EC spontaneous activity reveals reduced activation in W and SD vs. LE. by Alejandro Peinado (758770)

“…<p>A significant decrease in the overall intensity (<b>A</b>) of spontaneous events is apparent in W and SD slices. …”

Expression of antioxidant proteins is altered in cystic fibrosis. by Junnan Chen (270183)

“…Blue protein names indicate a decrease, while red names indicate an increase in expression in CF.…”

Increased susceptibility to DSS-induced colitis in <i>Oasis</i>−/− mice. by Kenta Hino (519150)

“…(F) HE (upper panels) and PAS (lower panels) staining of large intestines from WT and <i>Oasis</i>−/− mice exposed to 3.5% DSS for 5 days. Note that the <i>Oasis</i>−/− large intestine exhibited mucosal damage, degeneration of the mucosal epithelium, a decrease in the number of goblet cells, and an increase of crypt loss compared with those in WT large intestines. …”

The fraction of cooperators for different <i>ω</i> and <i>γ</i> based on different behavioral updating. by Xiaochen He (455300)

“…It increases as <i>ω</i> increases when <i>γ</i> > 0.5, but decreases as <i>ω</i> increases when <i>γ</i> < 0.5.…”

Increased phosphorylated Akt by inhibition of ERK_1,2 activation. by Natalia Dünner (465700)

“…<p>(A) Representative Western blots of phosphorylated Akt (p-Akt), total Akt, phosphorylated ERK_1,2 (p-ERK), total ERK_1,2 and β-actin in extracts from cells incubated for 60 min with 1×10⁻⁵ M U0126, 1×10⁻⁵ M PD98059 or vehicle. …”

Figure S1 - Amyloid Beta Resistance in Nerve Cell Lines Is Mediated by the Warburg Effect by Jordan T. Newington (223389)

“…<p><b>Treatment with oxamate or DCA decreases cell viability in Aβ resistant cells.</b> A significant decrease in cell viability in both PC12 (<b>A</b>) and B12 (<b>B</b>) resistant lines was observed after 48 hr concomitant exposure to Aβ (20 µM) and 20 mM oxamate (ox), a chemical inhibitor of LDHA, or Aβ (20 µM) and 2.5 mM dichloroacetate (DCA), a chemical inhibitor of PDK1 (*P<0.01; **P<0.05). …”

Identification of proteins that are differentially expressed in the activated T cells. by Wei-Yun Sheng (261744)

“…<p>Activation of T cells was done by cultivating PBL in the presence of PHA at 5 µg/ml for 1–3 days. The protein extracts from untreated controls (panels A and B) or PHA-treated cells (panels C and D) were electro-focused in a pH 4–7 (panels A and C) or in a pH 6–11 (panels B and D) IPG strip for the 1^st dimension and then separated in a 10% SDS-PAGE for the 2^nd dimension. …”