Riccardin D inhibited angiogenesis in intestinal polyps. by Hui-Ping Liu (290636)

Effects of vidarabine, V2E, V3E and V5E on AC activity in the heart of WT and AC5KO mice. by Kenji Suita (750993)

“…<p>(A) Vidarabine (Vida), V2E, V3E and V5E similarly and significantly decreased ISO (50 µmol/L)-stimulated AC activity in the WT heart in a dose-dependent manner. …”

Effects of insulin and IGF-I stimulation on the expression levels of bisecting GlcNAc <i>N</i>-glycans, in general and specifically on E-cadherin. by Julio Cesar Madureira de-Freitas-Junior (489189)

“…MDA-MB-435+E-cad cells stimulated with insulin (100 ng/mL) and IGF-I (50 ng/mL) showed a significant decrease of the overall levels of bisecting GlcNAc N-glycans. …”

Circular Dichroism analysis, PPIase activity and nickel regulation of <i>H</i>. <i>pylori</i> WT and mutant SlyD proteins. by Milica Denic (9987685)

Synaptic facilitation between tail SNs and MNs following 5-HT treatment declined during aging. by Andrew T. Kempsell (738294)

“…A single AP evoked in tail SNs by 50 ms injected current resulted in a monosynaptic EPSP in tail MNs. …”

Flavaglines Alleviate Doxorubicin Cardiotoxicity: Implication of Hsp27 by Yohann Bernard (198579)

“…Administration of our lead compound (FL3) to mice attenuated cardiomyocyte apoptosis and cardiac fibrosis, as reflected by a 50% decrease of mortality.</p> <h3>Conclusions/Significance</h3><p>These results suggest a prophylactic potential of flavaglines to prevent doxorubicin-induced cardiac toxicity.…”

Following treatment with BMP-7 polarization of monocytes into M2 macrophages increases as well as expression of anti-inflammatory markers. by Crystal Rocher (500661)

“…Scale bar  = 50 µm. Histogram B shows quantitative analysis of the percentage of cells expressing CD206 with a significant increase in the ACM+BMP7 group and a significant decrease in the ACM and ACM+BMP7+Foll groups; n = 5–6. …”

Cas4 family proteins are 5′-3′ exonucleases. by Jing Zhang (23775)

“…The reaction temperature was 55°C. B. Sso0001 (0.3 µM) was incubated with 3′ end labelled DNA 50mer (500 nM) in reaction buffer at 55°C and products were analysed at 1, 2, 3, 5 and 10 min. …”

Three major biochemical changes can be observed in cartilage neotissue maturation with the self-assembling process, which mirror known developmental trends for articular cartilage. by Gidon Ofek (377122)

Cell adhesion changes β-catenin distributions under Wnt stimulations. by Jiawen Chen (589546)

“…Given the truth that the mutant of Y654 reduces the binding affinity between cadherin and β-catenin and decrease the phosphorylation rate of Y142, we set the Y142 phosphorylation rate of Y654 mutant equals to 0.4, 0.2 and 0.1 of the original value in wild-type β-catenin <b>c)</b>. …”

Schematic representation of voxel-wise age- and symptom severity- related models. by Juergen Dukart (283449)

“…<p>a) Schematic representation of age-related changes in one voxel (in %) considering GM volume at the age of 50 years as baseline. b) Schematic representation of changes related to healthy aging (black line) and age-related differences in AD (red line) in one voxel. …”

Notch1 deletion in the corneal epithelium leads to progressive barrier impairment. by Asadolah Movahedan (434957)

“…<p>Notch1 knockout efficiency was evaluated by western blotting of pooled corneal epithelial sheets (N=8 per group) from conditional Notch1^-/- mice showing 64% to 70% decrease in Notch 1 expression comparing to epithelial sheets from WT littermates (A). …”

Nanomediated Stimulation: An Alternative to Brassinolide Hormone Replacement Therapy for Plant Resistance Activation by Hui Feng (174331)

Optimal parameters and goodness of fit across stages and modalities. by Fernando Lehue (22513473)

“…Notice the apparent “flipping" of the y axis for the coupling parameter, which arises because we are modeling a decrease in ACh as an increase in G. <b>(C)</b> Violin plots comparing the euccorrelation metric between the simulated and empirical FC matrices, in the optimal, across 50 seeds, for all stages (* for <i>p</i> < 10⁻³, ** for <i>p</i> < 10⁻⁴, *** for <i>p</i> < 10⁻²², **** for <i>p</i> < 10⁻⁵⁰, see Cohen’s D interpretation in Methods).…”

Atrasentan does not ameliorate established podocyte injury in adriamycin nephropathy. by Roderick J. Tan (483502)

“…(H) Representative glomerulus from mouse treated with adriamycin and sacrificed at 35 days (left panel). Atrasentan at a dose of 7 mg/kg (middle panel) or 20 mg/kg (right panel) did not improve the loss of linear staining for nephrin (white arrows), the areas of complete nephrin disruption (asterisk), or the decrease in WT1-positive nuclei (yellow arrowheads). …”

Response adaptation for non-identical stimuli in DSTN. by Angus F. Chapman (5240060)

“…<p><b>A)</b> Model sensory responses as a function of the presence of a preceding stimulus with an orientation difference of 90° and interstimulus interval of 100 ms, using <i>τ</i>_E= 100 ms, <i>τ</i>_S= 50 ms, and uniform suppressive pooling. …”

1999–2009 Trends in Prevalence, Unawareness, Treatment and Control of Hypertension in Geneva, Switzerland by Idris Guessous (43509)

“…Hypertension unawareness decreased from 35.9% to 17.7% (P<0.001). The decrease in hypertension unawareness was not paralleled by a concomitant absolute increase in hypertension treatment, which remained low (38.2%). …”

Endothelial-specific ablation of Serum Response Factor causes hemorrhaging, yolk sac vascular failure, and embryonic lethality-10 by Mary L Holtz (81433)

“…Blue stain in A and B is DAPI nuclear stain. Scale bars: A, B = 50 μm; C, D = 7.5 μm.…”

SAHA specifically down regulates <i>Hdac7</i> mRNA levels. by Caroline L. Benn (195214)

“…Error bars are S.E.M. (B, C) <i>Hdac7</i> expression level is shown as a relative expression ratio to the geometric mean of three housekeeping genes in (B) striatum and (C) cerebellum of 14 week old wild-type (Wt, white), <i>Hdac7+/−</i> knockdown (Hdac7) (grey), R6/2 (black) and R6/2 mice with <i>Hdac7</i>+/− knockdown (R6/2-<i>Hdac7</i>, striped) mice (n>8 per genotype). …”

Characterization of gemcitabine-resistant subclones. by Fredrik I. Thege (12646919)

“…BxGR-360C cells display remodeled actin cytoskeleton, including increased lamellipodia formation (top inset), and decreased E-cadherin localization to cell-cell junctions (bottom inset), scale bar 50 μm. i) Image analysis of E-cadherin enrichment at cell-cell junctions in BxGR-360C cells relative to BxPC3 cells. …”