DataSheet1_The AKT inhibitor, MK-2206, attenuates ABCG2-mediated drug resistance in lung and colon cancer cells.ZIP by Hai-Ling Gao (9501677)

“…However, MK-2206 (0.3 and 1 μM) significantly increased the anticancer efficacy of mitoxantrone, SN-38 and topotecan, in H460/MX20 and S1-M1-80 cancer cells, as indicated by a significant decrease in their IC50 values, compared to cells incubated with vehicle. …”

The Effect of Mg Morphology on the Irregular Behavior of the Electrochemical Quartz Crystal Microbalance in Mg[N(CF₃SO₂)₂]₂/glyme Soluti... by Fumihiro SAGANE (12410110)

“…From the results, we conclude that the specific Mg morphology causes the restoring force to the quartz substrate, resulting in the apparent mass decrease.…”

Continental and global effects of different Δ<em>T</em>_g levels by Dieter Gerten (557088)

“…The results suggest that already at a Δ<em>T</em>_g of 2 ° C and mainly in the subtropics, higher water scarcity would occur in >50% out of the 19 climate scenarios. …”

Homozygous <i>LKB1</i> deletions occur in majority of cervical cancer cell lines. by Shana N. Wingo (265345)

“…LKB1 protein is undetectable in lines harboring homozygous deletions and decreased by ∼50% in C4I, consistent with monoallelic loss.…”

Factors associated with morphometric brain changes in cognitively normal aging by Renata Eloah de Lucena Ferretti-Rebustini (6117596)

“…METHODS: A cross-sectional study of 414 subjects, ≥50 years old submitted to clinical assessment and brain autopsy, after informed consent, was carried out at the São Paulo Autopsy Service, Brazil. …”

Table_1_Clinical and Functional Genetic Characterization of the Role of Cardiac Calcium Channel Variants in the Early Repolarization Syndrome.XLSX by Xiu Chen (1880425)

“…Three cases (18.8%) had a family history of SCD or syncope. Eight patients (50.0%) had a single calcium gene rare variant. …”

PNA impairs CD5 expression in B-CLL cells and sensitizes to fludarabine-induced cell death. by Elena Cesaro (11424301)

Gene expression response to USF depletion and IR. by Kimberly S. Bellingham-Johnstun (21714063)

“…<p>(A and B) Venn diagrams of DEG transcripts that exhibited >1.50-fold increase (A) or >1.50-fold decrease (B) in expression in either USFKD no IR or USFKD 7d IR cells relative to sshRNA no IR. …”

Effects of FAK inhibitor Y15 during ovulation <i>in vivo</i>. by Hiroya Kitasaka (4840218)

Mid-point for open-ended income category and the effect of equivalence scales on the income-health relationship by Roger Keller Celeste (6186155)

“…The median mid-point was R$ 14,523.50 and the mean, R$ 24,507.10. When per capita income was applied, 53% of the population were below the poverty line, compared with 15% with equivalized income. …”

Production of infectious HCV in cell culture. by Deborah L. Diamond (255229)

“…The reason for these decreases is unclear, but may be related to a decrease in the number of cells capable of producing high levels of virus.…”

Toll signaling in the Drosophila larval fat body shifts programs of anabolic lipid metabolism and dysregulates nutrient storage by Brittany Martínez (8728753)

“…However, we observe 50% decreases in fat body transcript levels of both <i>lipin</i>, a phosphatidic acid phosphatase,<i> </i>and<i> midway, </i>the homolog of diacylglycerol acyltransferase, both of which carry out triglyceride synthesis. …”

Cerebral Synaptosomal Purinergic Receptors were Downregulated in the MIA Model and Restored to Normal by Antipurinergic Therapy. by Robert K. Naviaux (256148)

“…(B) P2Y2 receptor expression was decreased by over 50% by gestational poly(IC) exposure and normalized by suramin treatment (Sal-Sal = 100+/−7.3%; Sal-Sur = 62+/−4.6%; PIC-Sal = 48+/−4.7%; PIC-Sur = 84+/−4.7%; one-way ANOVA F(3,12) = 18.1; p<0.0001; n = 4–5 males per group). …”

Validation of complete model with trafficking and phosphorylation parameters. by Lindsay Wendel Clegg (754229)

“…TIME cells, [V] = 50 ng/mL, measurements taken at t = 5 min. In the model, the experimentally observed decrease in VEPTP expression to 20% of control values with VEPTP siRNA was simulated by decreasing the dephosphorylation rate for Y951 and Y1175 by a factor of 5 on the cell surface. …”

Effect of miR-141 on growth and invasion of HCC cell in vitro. by Ying Liu (18461)

Prognosis for Hospitalized Patients with Systemic Lupus Erythematosus in China: 5-Year Update of the Jiangsu Cohort by Xuebing Feng (293563)

“…<div><p>Objective</p><p>To identify early signs associated with poor prognosis in Chinese patients with systemic lupus erythematosus (SLE) through a large population-based follow-up study.</p><p>Methods</p><p>Medical records of > 2,500 SLE patients that first hospitalized between 1999–2009 were collected from 26 centers across Jiangsu province, China, and entered into a database. …”

Effects of age of exercise onset on body composition across the lifespan. by Agnieszka Mika (306138)

TLR4 and NF-κB signaling pathway is required for the reduction of let-7b expression in response to <i>H.pylori</i> infection. by Gui-gen Teng (380044)

“…<p>(A) TKA-242 (1 uM) decreased the expression of TLR4 protein in AGS and GES-1 cells with <i>H.pylori</i>-infection. …”

SOCS3 regulated the fate of HSCs. by Yu-xiao Liu (146872)

“…Bar = 50 μm. (B) BFU-E and CFU-E derived from shSOCS3-1 CD34⁺ cells. …”

Mechanism of SFK phosphorylation and negative regulation of PKA in chicken sperm. by Chathura Priyadarshana (9635328)

“…<p>Sperm were incubated with 0–50 μM H-89 (PKA inhibitor), 25 μM KH7 (sAC inhibitor), 50 μM MDL (tmAC inhibitor), 0–250 μM PTP inhibitor, or EGTA-AM in the presence or absence of SKI606 and SU6656 and then subjected to immunodetection for p-SFK-Y416 or p-PKAs. …”