Tankyrase inhibitors promote inclusion of axin and TNKS into insoluble complexes. by Estefania Martino-Echarri (2548186)

“…<p><b>A.</b> NIH 3T3 cells were left untreated (- CSK) or washed for 5 min with 0.2% Triton X-100 containing MT-buffer (+CSK) to permeabilize the plasma membrane and remove soluble proteins, before immunolabeling with fluorescent antibodies for axin and tubulin. …”

Data_Sheet_3_Aspartic Acid Residue 51 of SaeR Is Essential for Staphylococcus aureus Virulence.PDF by Tyler K. Nygaard (323813)

“…These findings corresponded to a significant decrease in cytotoxicity against human erythrocytes and polymorphonuclear leukocytes, the ability to block human myeloperoxidase activity, and pathogenesis during murine soft-tissue infection. …”

Targeted alteration of the low-<i>γ</i> peak and slow fluctuations. by Hannah Bos (3220512)

“…<b>D</b> Instantaneous firing rate of population 5E (binning window: 15 ms), in a time segment of 3 s, for the three parameter regimes introduced in B (<i>α</i> decreases from top to bottom). …”

TXNIP targets glycolysis and the pentose phosphate pathway. by Stephanie Kim (2560966)

“…HEK293T cells were transduced with lentiviruses carrying vector control or TXNIP gene and were collected 48 hrs post transduction and prepared for LC-MS metabolomics. In TXNIP expressing cells, metabolites that increased were displayed in red and metabolites that decreased were displayed in blue. …”

Table 1_The kinetic behavior of matrine in pig intestinal lumen after oral administration and its physiologically based pharmacokinetic modeling.docx by Bo Yang (104813)

“…In experiment 2, 25 pigs were administered with MT at 50 mg/kg/d by oral gavage for 5 d. Intestinal contents were collected at predetermined times and analysed by liquid chromatography tandem mass spectrometry (LC–MS/MS) method. …”

Thermal-dependent product specificity over time. by Gabriel Piedrafita (155328)

“…Shown is the cumulative product concentration normalized to the total product quantified at each time by targeted LC/MS. As temperature decreases, the loss of specificity in R5P formation detected at higher temperatures ceases and R5P becomes the predominant sugar phosphate product, also at long term (70% to 80% of total product; blue area). …”

Sleep Quality Associated with Habitual Physical Activity Level and Autonomic Nervous System of Smokers by Iara Buriola Trevisan (6128888)

“…Furthermore, the less active group presented decreased parasympathetic modulation [HF (un; p=0.049); RMSSD (ms; p=0.047) and SD1 (ms; p=0.047)] and an increased LF (un) index (p=0.033) and LF/HF ratio (p=0.040). …”

Video1_How about running on Mars? Influence of sensorimotor coherence on running and spatial perception in simulated reduced gravity.MP4 by Marie Keime (16712952)

“…Also, while vection was found to decrease in case of a coherent visuomotor coupling at 100% BW (i.e., post-exposure influence), it remained unaffected by the visual context at 38% BW. …”

In microglia, C1 reduced NO release triggered by IFNγ and PolyIC, and did not affect LPS induced cytokine release. by Philipp Jordan (9364068)

“…<p><b>a)</b> Stimulation of microglia with IFNγ (100 ng/mL) for 48 hours (left, in black) and PolyIC (100 μg/mL) for 24 hours (right, in black) caused a significant increase in the production of NO (p<0.0001) in comparison with unstimulated control (white bar). …”

Estimating Influence of Cofragmentation on Peptide Quantification and Identification in iTRAQ Experiments by Simulating Multiplexed Spectra by Honglan Li (328866)

“…A simple method of filtering out cofragmented spectra with less than 100% precursor isolation purity (PIP) would decrease the coverage of iTRAQ/TMT experiments. …”

Data_Sheet_1_Use of reverse osmosis concentrate for mitigating greenhouse gas emissions from pig slurry.DOCX by Seongwon Im (12531192)

“…<p>Due to the high global warming potential (GWP) in a short time scale (GWP100 = 28 vs. GWP20 = 86), mitigating CH₄ emissions could have an early impact on reducing current global warming effects. …”

MF induced EGFR interaction. by Xia Wu (203682)

“…C: The DEP FI decrease percentages in EGFR monomer solution with pretreatment of PD of a serial of concentration. …”

Effect of SRF on the activity of CArG-containing minimal promoter by Céline René (10829)

“…Densitometric analysis showed a substantial decrease of endogenous SRF. Right panel: the luciferase activity value 100 was assigned to the samples co-transfected with the control siRNA. *, < 0.05 versus WT or 3XSRE.…”

Pcl3 promotes ESC self-renewal. by Julie Hunkapiller (177548)

“…Graph represents average expression from 3–6 different clones. (B) A portion of cells transduced with <i>Pcl3</i> shRNA, but not scramble shRNA, are larger, flatter, and less dense, signifying a decrease in ESC cell morphology. …”

Upper extremity orthopedic softball injuries presenting to the emergency department: epidemiology across the lifespan by David F. Painter (12884672)

“…The average incidence rate of UE injuries from 2012–2021 was 187.9 per 100,000 persons, with a significant decrease in injury incidence across the timespan (<i>p</i> < .001). …”

ErbB signaling is implicated in generation of neurons and mitoses in the sub-ventricular zone. by Tomomi Sato (301255)

“…Impaired neurogenesis and a decrease in pH3-positive mitotic cells in the SVZ of AG1478-treated Tg(<i>pou4f1-hsp70l</i>:<i>GFP;-8</i>.…”

Determination of mitochondrial temperature in intact human cells. by Dominique Chrétien (217681)

“…The MTY fluorescence reached at the end of phase I was significantly different (<i>n</i> = 10; ***) from the starting value of 50%, whilst the final value in phase IV was not. (D) (a) Linear increase of fluorescence of HEK293 cells (preloaded for a minimum of 10 min, with 100 nM MTY), according to cell number (using cell protein concentration as surrogate parameter); (b) Maximal rate of decrease of MTY fluorescence (percentage, blue circles, corresponding with mitochondrial warming) is not significantly affected by cell number, whereas initial fluorescence increase in the presence of cyanide (percentage, green circles, corresponding with initial rate of mitochondrial cooling) is modulated by cell number (values at the three cell concentrations tested were significantly different from each other). …”

Table_2_Transcriptomic Profiles of Senegalese Sole Infected With Nervous Necrosis Virus Reassortants Presenting Different Degree of Virulence.docx by Alejandro M. Labella (5521130)

“…The wild-type reassortant wSs160.03, isolated from Senegalese sole, has been proven to be more virulent to sole than the parental genotypes (RGNNV and SJNNV), causing 100% mortality. Mutations at amino acids 247 (serine to alanine) and 270 (serine to asparagine) in the wSs160.03 capsid protein have allowed us to obtain a mutant reassortant (rSs160.03_247+270), which provokes a 40% mortality decrease. …”

Table_1_Transcriptomic Profiles of Senegalese Sole Infected With Nervous Necrosis Virus Reassortants Presenting Different Degree of Virulence.docx by Alejandro M. Labella (5521130)

“…The wild-type reassortant wSs160.03, isolated from Senegalese sole, has been proven to be more virulent to sole than the parental genotypes (RGNNV and SJNNV), causing 100% mortality. Mutations at amino acids 247 (serine to alanine) and 270 (serine to asparagine) in the wSs160.03 capsid protein have allowed us to obtain a mutant reassortant (rSs160.03_247+270), which provokes a 40% mortality decrease. …”

Table_6_Transcriptomic Profiles of Senegalese Sole Infected With Nervous Necrosis Virus Reassortants Presenting Different Degree of Virulence.docx by Alejandro M. Labella (5521130)

“…The wild-type reassortant wSs160.03, isolated from Senegalese sole, has been proven to be more virulent to sole than the parental genotypes (RGNNV and SJNNV), causing 100% mortality. Mutations at amino acids 247 (serine to alanine) and 270 (serine to asparagine) in the wSs160.03 capsid protein have allowed us to obtain a mutant reassortant (rSs160.03_247+270), which provokes a 40% mortality decrease. …”