Validation of the primary screen hits with secondary luciferase-based invasion and red-green invasion assays. by Rajshekhar Y. Gaji (417441)

“…The values obtained with non-targeting siRNA controls were set at 100% invasion. A total of 81 genes (red asterisks) showed significant decrease (<i>p</i><0.05, one sample <i>t</i>-test) in parasite invasion compared to NTsiRNA controls. …”

Expression of MMP7 and TIMP1 in wounds. by Katharina Sommer (463202)

“…Septic animals show a significant decrease in MMP7 expression on day 2 and 6 compared to control mice. …”

Ca²⁺ sparklets in DSM are affected by, but not dependent upon, signals from the SR. by Peter Sidaway (190696)

“…In the presence of the VGCC antagonist R-(+)-Bay K 8644 (1 μM) and CPA (10 μM), there was a significant decrease in the frequency (D) but not amplitude (E) of Ca²⁺ sparklets. …”

Glycosylation inhibitors block thrombin-induced sRBC adhesion to HUVECs. by Pushpankur Ghoshal (580530)

“…The level of sRBC adhesion to untreated HUVECs was set to 100%. **, p<0.0001 <b>B</b>. Glycosylation inhibitors decrease thrombin-induced sRBC adhesion to HUVECs. …”

Transcripts differentially expressed in response to overexpression of and in response to overexpression of human , grouped according to functional classes by Haiqiong Montalta-He (54730)

“…Positive values indicate that the relative expression level of a gene is increased (upregulated) following overexpression and negative values indicate a decrease (downregulated). …”

Anti-HBV activity of CDM-3008 in primary cultured human hepatocytes. by Yutaka Furutani (5620139)

“…(C) Measurement of HBV DNA copies in PXB cells after 7 days of CDM-3008 treatment. HBV DNA was decreased with 0.1–100 μM CDM-3008 in a dose-dependent manner. …”

Histology of islet allografts at day 10, 17, 24, and 31 after transplantation in non-diabetic mice. by Jyuhn-Huarng Juang (407970)

“…There was profound immune cell infiltration at day 10 and 17, and a decrease in graft size at day 24 and 31 in the CSPIO-labeled islet graft. …”

Gene expression in primary human skeletal muscle cells after treatment with acylcarnitines. by Rainer Lehmann (141280)

“…<p>mRNA expression of PGC-1α (A), CPT1b (B), CD36 (C), COX1 (D) and AngPL-4 (E) related to β-actin mRNA levels after incubation with 100 µM L-carnitine (L-C), an equimolar mixture of C8:0-, C10:0- and C12:0-acylcarnitine (total 100 µM; AC), 60 µM palmitate (p), or p and AC as indicated. …”

Effect of galactose treatment on oleic acid metabolism. by Eili Tranheim Kase (177084)

“…Suppressibility, defined as the ability of the cells to decrease oleic acid oxidation by acutely added glucose, was calculated as: [(1-(oxidation of oleic acid at 5 mM glucose/oxidation of oleic acid at no glucose added))×100%]. …”

Hormone addition results in chromatin changes at individual GR-regulated genes. by Chuong D. Pham (111374)

“…We calculate that a nucleosome/bare ratio of 1.0 corresponds to ∼50% nucleosome occupancy, while a value of 2.1 corresponds to 100% occupancy (e.g. a nucleosome covering a given location on all gene copies). …”

The effect of ribavirin (Rib) and guanosine (Gua) on HCV infectious progeny production and intracellular viral RNA and nucleotide pools. by Ana M. Ortega-Prieto (446894)

“…(c) Left: intracellular amount of the four nucleoside-triphosphates, following 72 h of exposure to either Rib or Gua, as indicated at the bottom. Right: decrease or increase of nucleotide concentration as a result of exposure to Gua or Rib; note that the maximum decrease possible is 100%. …”

Effective recovery time and synaptic integration time during scratching. by Rune W. Berg (54068)

“…(C) Estimates of eSIT and eRT versus position of the template distribution relative to the spike from (B) (broken lines represent mean values eSIT = 12.1 ms, eRT = 8.7 ms). (D) The number of traces in template distribution decreases with window length (from same data as in (B) and (C)).…”

Repeat the detection experiment. by Yingying Liu (360782)

K_v4 is Required for Maintaining Excitability in <i>Drosophila</i> Neurons. by Yong Ping (233004)

“…<p><i>A</i>, Representative firing patterns recorded with current injections of 40, 60, and 100 pA from wild-type (wt) and DNK_v4 (DN) neurons. …”

Metabolic profiling by tandem mass spectrometry reveals distinct metabolite signatures of cells exposed to pro-inflammatory cytokines vs. the apoptotic inducer camptothecin. by J. Jason Collier (130356)

“…<p><i>A</i>. 832/13 cells were exposed to 1 ng/mL IL-1β+100 U/mL γ-IFN or 2 µM camptothecin for 6 h. …”

Fasting Conceals Rapid Diet-Induced Inhibition of PDH. by Clair Crewe (467358)

“…Mitochondria were incubated with 100 µM pyruvate and 1.0 mM malate. State 3 respiration was initiated by addition of 0.25 mM ADP. …”

<i>Tg</i>ApiAT1 protein abundance is regulated by [Arg] in the growth medium. by Esther Rajendran (6321464)

“…(<b>E</b>) Volcano plot depicting log₂ fold change vs -log₁₀ <i>P</i> values of change in protein abundance in a SWATH MS-based proteomic analysis of parasites grown at 50 μM vs 1.15 mM Arg (n = 5). …”

Neurotensin activates orexin neurons. by Naoki Furutani (169799)

“…Neurons were current-clamped and the current was stepped from –240 pA to +280 pA (with increments of 40 pA with a duration of 100 ms). …”

The effect of mycophenolic acid (MPA) and guanosine (Gua) on HCV infectious progeny production and intracellular nucleotide pools. by Ana M. Ortega-Prieto (446894)

“…(b) Left: Intracellular amount of the four nucleoside-triphosphates, following 72 h of exposure to either MPA or Gua, as indicated at the bottom. Right: decrease or increase of nucleotide concentration as a result of exposure to Gua or MPA; note that the maximum decrease possible is 100%. …”

Magnitude of within-object color coding within each CNN layer. by JohnMark Taylor (8329326)

“…Regression analyses were conducted to test for an aggregate increase or decrease in color representation over the course of processing; upward- and downward-facing arrows denote a significant increase or decrease respectively, with the level of significance denoted by the adjacent asterisks. …”