CLUES captures bivalent chromatin status, core regulation genes circuitry and novel self-renewal and pluripotency regulators of mouse ES cells by integrating prioritized broad E-si... by Chao Wu (199897)

“…The heat-map is rank-ordered by broad H3K4me3 E-signals. d. The top 100 genes revealed by the CLUES integrated analysis are significantly enriched at the top of the list from a CRISPR/Cas9 negative selection genetic screen (Kolmogorov–Smirnov test, p<0.002). …”

αIIbβ3-deficient platelets fail to spread, form thrombi, or efficiently secrete granule contents over immobilized IgG. by Huiying Zhi (706852)

“…<b>(E)</b> Anticoagulated, mepacrine-labeled whole blood from αIIbβ3^+/+/FcγRIIa^pos and αIIbβ3^-/-/FcγRIIa^pos mice was perfused over 100 μg/mL IgG-coated flow chambers at a shear rate of 5 dynes/cm² and images acquired using epifluorescence microscopy. …”

Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated systematic revi... by Yiran Wang (1492303)

“…No significant differences were found for the risk of overall neoplasm (RR = 1.08, 95% CI: 0.99 to 1.19, I² = 23%) in patients with SGLT-2i treatment compared with non-users. However, decreased risk of pulmonary neoplasm (RR = 0.83, 95% CI: 0.69 to 0.99, I² = 0.0%) was observed in SGLT-2i users compared to non-users, while increased risk of prostate neoplasm in SGLT-2i users was found (RR = 1.21, 95% CI: 1.00 to 1.47, I² = 0.0%).…”

Table1_Synthesis of green zinc‐oxide nanoparticles and its dose‐dependent beneficial effect on spermatozoa during preservation: sperm functional integrity, fertility and antimicrob... by Meiaishan Eliezer Lyngdoh (18013783)

“…This study demonstrates the beneficial effect of zinc oxide nanoparticles (ZnO-NPs) as an additive to semen extenders to improve semen quality, fertility, and antibacterial activity during liquid preservation in a boar model.</p><p>Methods: Initially, to find out the safe concentration of ZnO-NPs in sperm cells, a wide range of ZnO-NP concentrations (0, 5, 10, 50, 100, 500, and 1,000 μM) were co-incubated with sperm at 37°C for a cytotoxic study. …”

Image1_Synthesis of green zinc‐oxide nanoparticles and its dose‐dependent beneficial effect on spermatozoa during preservation: sperm functional integrity, fertility and antimicrob... by Meiaishan Eliezer Lyngdoh (18013783)

“…This study demonstrates the beneficial effect of zinc oxide nanoparticles (ZnO-NPs) as an additive to semen extenders to improve semen quality, fertility, and antibacterial activity during liquid preservation in a boar model.</p><p>Methods: Initially, to find out the safe concentration of ZnO-NPs in sperm cells, a wide range of ZnO-NP concentrations (0, 5, 10, 50, 100, 500, and 1,000 μM) were co-incubated with sperm at 37°C for a cytotoxic study. …”

SGS-LTER Transect Study - Organic Carbon in Soils across Toposequences on the Central Plains Experimental Range, Nunn, Colorado, USA 1983-1984 by Eugene Kelly (17483304)

“…Similarly, the mass of organic C within the surface meter of soil often did not increase with decreasing elevation across a toposequence. Mass of organic C was found to range from 2.5 kg m^-3 on terrace escarpments to 10.7 kg m^-3 on sandy uplands. …”

Expression and distribution of <i>Drosophila mnb</i> in adults in relation to <i>sNPF</i>, <i>sNPFR1</i>, and feeding. by Seung-Hyun Hong (136797)

“…<p>(A) <i>mnb</i> mRNA prepared from fly heads was measured by RT-qPCR. …”

C2CD3 regulates spatial organization of centriole architecture. by Eloïse Bertiaux (5309927)

“…For CEP162-positive centrioles: siCTRL = 100% ± 0, siC2CD3 = 50.83% ± 4.31. Overall CEP162 fluorescence decreased in siC2CD3 (<i>n</i> = 31, 1.47 ± 0.39 AU.) vs. siCTRL (<i>n</i> = 35, 1.68 ± 0.51 AU), unpaired <i>t</i> test *** <i>P</i> value = 0.0008. …”

Time-course of mRNA expression of IGF-system genes and the activation levels of signalling mediators in the E18.8 cochlea. by Hortensia Sanchez-Calderon (186893)

“…Films were scanned, densitometry performed by using ImageJ software and the levels were normalised by giving a value of 100 to the <i>Igf1^+/+</i> mouse samples. …”

The effects of Hh protein and agonist on vertebrate Smo and Ptc proteins by Maria Frank-Kamenetsky (26382)

“…Blots in (b) and (c) were reprobed with anti-tubulin antibody as a sample loading control. Anti-HA protein blot of cell extracts, fractionated by SDS-polyacrylamide gel electrophoresis, from cells treated with decreasing concentrations of Hh protein (lane 1, 100 nM; lane 2, 50 nM; lane 3, 25 nM; lane 4, 12.5 nM; lane 5, 6.25 nM; lane 6, 3.12 nM), or with vehicle (lane 7), or with increasing concentrations of Hh-Ag 1.2 (agonist; lane 8, 15 nM; lane 9, 31.25 nM; lane 10, 62.5 nM; lane 11, 250 nM; lane 12, 500 nM; lane 13, 1 μM) for 22 hours. …”

Shape Memory Superelastic Poly(isocyanurate-urethane) Aerogels (PIR-PUR) for Deployable Panels and Biomimetic Applications by Suraj Donthula (1441132)

“…After the first cycle, strain recovery (a measure of fatigue) improved from 80−90% to about 100%, and the fill factor, a cumulative index of performance, reached 0.7, which is in the range of fast elastomers. …”

Inhibition of the Hedgehog pathway partially rescues pancreas formation in pancreas with activated β-catenin signaling. by Jose Luis Muñoz-Bravo (3220134)

“…Data are presented as mean ± SEM. ** p< 0.01 (one-way ANOVA). Scale bars 100 μm, (in A for A-B; in E for E-G; in H for H-J).…”

Shape Memory Superelastic Poly(isocyanurate-urethane) Aerogels (PIR-PUR) for Deployable Panels and Biomimetic Applications by Suraj Donthula (1441132)

“…After the first cycle, strain recovery (a measure of fatigue) improved from 80−90% to about 100%, and the fill factor, a cumulative index of performance, reached 0.7, which is in the range of fast elastomers. …”

Mitochondrial ROS generated by reverse electron transport in muscles is necessary for critical period heat stress to change NMJ development. by Daniel Sobrido-Cameán (5049743)

“…</i> 25°C control) leads to increased aCC NMJ terminal size and decreased postsynaptic GluRIIA, while not affecting subunit GluRIIB expression. …”

Shape Memory Superelastic Poly(isocyanurate-urethane) Aerogels (PIR-PUR) for Deployable Panels and Biomimetic Applications by Suraj Donthula (1441132)

“…After the first cycle, strain recovery (a measure of fatigue) improved from 80−90% to about 100%, and the fill factor, a cumulative index of performance, reached 0.7, which is in the range of fast elastomers. …”

Lanthanide Complexes of Triethylenetetramine Tetra-, Penta-, and Hexaacetamide Ligands as Paramagnetic Chemical Exchange-Dependent Saturation Transfer Contrast Agents for Magnetic... by Dirk Burdinski (379996)

“…In chemical exchange-dependent saturation transfer (CEST) ¹H NMR experiments, most of the above complexes exhibit multiple strong CEST peaks of the paramagnetically shifted amide protons spread over a >100 ppm chemical shift range. The effective CEST effect of the studied thulium complexes strongly depends on temperature and pH. …”

Depletion of ribosome biogenesis factors inhibits the regenerative behavior of hinge cells. by Michelle Ledru (6593078)

“…Controls show robust cell fate change and translocation after IR (G) but RpI135 depletion in the hinge inhibited IR-induced cell fate plasticity (I). Scale bar = 100 microns. (J) Discs such as those shown in (F-I) were quantified for total RFP^-GFP⁺ area in the pouch area as in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009989#pgen.1009989.g004" target="_blank">Fig 4</a> and normalized to the RFP⁺GFP⁺ hinge area to account for variations in disc size. …”

Fig 5 - by Adam Lampert (413952)

“…As in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1011996#pcbi.1011996.g004" target="_blank">Fig 4</a>, the main (middle) panel shows the annual cost of treatment associated with the optimal treatment, ACT*, as a function of the target propagation speed <i>v</i> for three choices of <i>kλ</i>_<i>0</i>. …”

Over-expression of <i>Atg1</i> in the gut, fat body and Malpighian tubules extends lifespan. by Ivana Bjedov (75652)

“…<p>(A) Over-expression of Atg1 in the gut and fat body under control of the inducible <i>S</i>_<i>1</i><i>106</i> GeneSwitch driver using a range of RU concentrations. …”

Plasma membrane vesicles (ROV) of cancer cells can produce ATP and PP_i with acid gradient. by Gautam Dhar (723875)

“…<p>(A) Schematic of the experiment showing assay of bead-bound ROV. …”