Image_1_Differential Profile of Systemic Extracellular Vesicles From Sporadic and Familial Alzheimer’s Disease Leads to Neuroglial and Endothelial Cell Degeneration.TIFF by Juan Villar-Vesga (4900768)

“…We found increase CLN-5 spots with vesicular morphology in the abluminal portion of vessels from SAD patients. …”

Data_Sheet_1_Enterovirus 71 Suppresses miR-17-92 Cluster Through Up-Regulating Methylation of the miRNA Promoter.docx by Yuxuan Fu (4437475)

“…Overexpression of hsa-miR-17∼92 inhibited, while inhibition of endogenous hsa-miR-17∼92 facilitated EV71 replication. We identified two sequences located at nt 3024 to 3038 and nt 2838 to 2862 of the EV71 (strain FY0805) genome as potential targets for hsa-miR-17-5p and miR-19a/b, respectively, which were validated by luciferase reporter assays and Western blot. …”

Supplementary Material for: MDM2 is essential to maintain the homeostasis of epithelial cells by targeting p53 by Wang S. (3116754)

“…We demonstrated that heterozygous Mdm2 gene-deleted mice were highly susceptible to protease allergen papain-induced pulmonary inflammation characterized by increased ILC2 numbers, IL-5 and IL-13 cytokine levels, and lung pathology. …”

Table 1_Childhood cancer patients' experiences of a structured exercise program. A qualitative study using reflexive thematic analysis.pdf by Dennis Wilke (20936606)

“…</p>Objectives<p>To explore patients' and parental experiences of participating in a structured, individualized exercise program lasting 8–10 weeks during intensive treatment in a German childhood cancer center as part of the clinical trial FORTEe – Get strong to fight childhood cancer.</p>Methods<p>We conducted open qualitative interviews (n = 11) with children and adolescents (n = 6) and parents (n = 5), as well as participant observation during exercise sessions (n = 10). …”

Presentation1_A low-cost recombinant glycoconjugate vaccine confers immunogenicity and protection against enterotoxigenic Escherichia coli infections in mice.pdf by Asher J. Williams (14705734)

“…Despite significant efforts over the past several decades, an affordable vaccine that appreciably decreases mortality and morbidity associated with ETEC infection among children under the age of 5 years remains an unmet aspirational goal. …”

Measuring biological age to assess colony demographics in honeybees by Cedric Alaux (5176733)

“…We found that the biological age of bees from the conventional apiary progressively decreased from the spring (17 days) to the fall (6 days). …”

Table_1_Differential Profile of Systemic Extracellular Vesicles From Sporadic and Familial Alzheimer’s Disease Leads to Neuroglial and Endothelial Cell Degeneration.XLSX by Juan Villar-Vesga (4900768)

“…We found increase CLN-5 spots with vesicular morphology in the abluminal portion of vessels from SAD patients. …”

Image_3_Differential Profile of Systemic Extracellular Vesicles From Sporadic and Familial Alzheimer’s Disease Leads to Neuroglial and Endothelial Cell Degeneration.TIFF by Juan Villar-Vesga (4900768)

“…We found increase CLN-5 spots with vesicular morphology in the abluminal portion of vessels from SAD patients. …”

Asparagine-based production of hydrogen peroxide triggers cell death in the diatom <i>Phaeodactylum tricornutum</i> by Javier A. Contreras (8762379)

“…Using microscopic analyses and physiological assays, we showed that while asparagine fuelled photosynthetic growth, its supplementation to NO₃⁻ medium significantly decreased the culture’s cell density and photosynthetic capacity (F_v/F_m) during the stationary phase of the growth cycle. …”

Image_4_Differential Profile of Systemic Extracellular Vesicles From Sporadic and Familial Alzheimer’s Disease Leads to Neuroglial and Endothelial Cell Degeneration.TIFF by Juan Villar-Vesga (4900768)

“…We found increase CLN-5 spots with vesicular morphology in the abluminal portion of vessels from SAD patients. …”

Supplementary Material for: Persistently Altered Metabolic Phenotype following Perinatal Excitotoxic Brain Injury by Blaise B.J. (4019153)

“…Understanding the underlying processes of the acute effects of excitotoxicity and its persistence during brain maturation provides an opportunity to identify mechanistic or diagnostic biomarkers, thus enabling and designing possible therapies. We applied mass spectrometry to provide metabolic profiles of brain tissue and plasma over time following an excitotoxic lesion (intracerebral ibotenate) to the neonatal (postnatal day 5) mouse brain. …”

Arachidonic Acid Drives Postnatal Neurogenesis and Elicits a Beneficial Effect on Prepulse Inhibition, a Biological Trait of Psychiatric Illnesses by Motoko Maekawa (36394)

“…Our results are: (1) an independent model animal, <em>Pax6</em> (+/−) rats, exhibited PPI deficits along with impaired postnatal neurogenesis; (2) methylazoxymethanol acetate (an anti-proliferative drug) elicited decreased neurogenesis even in postnatal period, and PPI defects in young adult rats (10 weeks) when the drug was given at the juvenile stage (4–5 weeks); (3) administering ARA for 4 weeks after birth promoted neurogenesis in wild type rats; (4) raising <em>Pax6</em> (+/−) pups on an ARA-containing diet enhanced neurogenesis and partially improved PPI in adult animals. …”

Image_2_Differential Profile of Systemic Extracellular Vesicles From Sporadic and Familial Alzheimer’s Disease Leads to Neuroglial and Endothelial Cell Degeneration.TIFF by Juan Villar-Vesga (4900768)

“…We found increase CLN-5 spots with vesicular morphology in the abluminal portion of vessels from SAD patients. …”

Image_1_Transgenic zebrafish as a model for investigating diabetic peripheral neuropathy: investigation of the role of insulin signaling.TIF by Dong-Won Lee (2208223)

“…To achieve this, we generated Tg (ins:gal4p16);Tg (5uas:epNTR-p2a-mcherry) zebrafish using an enhanced potency nitroreductase (epNTR)-mediated chemogenetic ablation system, which showed highly efficient ablation of pancreatic β-cells following treatment with low-dose metronidazole (MTZ). …”

Stochastic Formation of Quantum Defects in Carbon Nanotubes by Chen Ma (714759)

“…For bulk samples, the bandgap emission (E₁₁) of monochiral (6,5)-SWCNTs decreases, and the defect-related emission feature (E₁₁*) increases with diazonium salt concentration and represents a proxy for the defect number. …”

Image_2_Differential Profile of Systemic Extracellular Vesicles From Sporadic and Familial Alzheimer’s Disease Leads to Neuroglial and Endothelial Cell Degeneration.TIFF by Juan Villar-Vesga (4900768)

“…We found increase CLN-5 spots with vesicular morphology in the abluminal portion of vessels from SAD patients. …”

Table_2_Differential Profile of Systemic Extracellular Vesicles From Sporadic and Familial Alzheimer’s Disease Leads to Neuroglial and Endothelial Cell Degeneration.XLSX by Juan Villar-Vesga (4900768)

“…We found increase CLN-5 spots with vesicular morphology in the abluminal portion of vessels from SAD patients. …”

Hypoxia Regulates mTORC1-Mediated Keratinocyte Motility and Migration via the AMPK Pathway by Tiantian Yan (3625496)

“…Importantly, hypoxia-activated mTORC1 was accompanied by the AMPK downregulation, and we found that the AMPK pathway activators Metformin (Met) and 5-Aminoimidazole-4-carboxamide 1-β-D-ribofuranoside (AICAR) decreased the mTORC1 activity, cell motility and lateral migration. …”

Mortality and potential years of life lost by road traffic injuries in Brazil, 2013 by Silvânia Suely Caribé de Araújo Andrade (4657741)

“…More than half of the people who have died because of road traffic injuries were of black race/skin color, young adults (24.2%), individuals with low schooling (24.0%), and motorcyclists (28.5%). The mortality rate in the triennium 2011-2013 decreased 4.1%, but increased among motorcyclists. …”

Differential Analysis of Ovarian and Endometrial Cancers Identifies a Methylator Phenotype by Diana L. Kolbe (179848)

“…For comparison within the endometrioid subtype we added 6 primary uterine endometrioid tumors and 5 endometrioid metastases from uterus to ovary. …”