Decreased α-cell mass and early structural alterations of the exocrine pancreas in patients with type 1 diabetes: An analysis based on the nPOD repository by Fidéline Bonnet-Serrano (4782546)

“…Results were expressed as mean ±SD.</p><p>Results</p><p>An automated quantification method was set up using the R software and was validated by quantification of β-cell mass, a well characterized parameter. β-cell mass was 29.6±112 mg in patients and 628 ±717 mg in controls (p<0.0001). α-cell mass was 181±176 mg in patients and 349 ±241mg in controls (p<0.0001). …”

Western blots showing increased CaM, CaN and NCX1 levels, and decreased SERCA2 levels in human heart failure. by Raquel Cortés (331424)

Decrease of excitability in small IB4-positive TG neurons over-expressing TRESK channels. by Zhaohua Guo (383295)

Genkwanin exerts anti-inflammatory effects mainly through decreasing miR-101 production. by Yuan Gao (159945)

Decreased survival, splenomegaly, thrombocytopenia and megakaryocyte alterations in SCID-Rasa3^−/− mice. by Patricia Molina-Ortiz (167505)

Luteolin decreases production of IL-6, IL-8 and VEGF in TNF-triggered primary NHEKs. by Zuyi Weng (109988)

Imatinib induces the differentiation of human normal erythroblasts and decreases cell surface expression of c-Kit. by Diane D'allard (405441)

SHIP-1 decreases NOD2-induced NF-κB activation in epithelial cells. by Claude Condé (150801)

<i>Pf-Rel</i> knockdown decreased the <i>Nacrein</i> gene expression level. by Juan Sun (439334)

“…Both <i>Nacrein</i> and <i>Pf-Rel</i> mRNA expression level in controls are attributed a relative value of 1.0. tm-3-15 and tm-6-15: samples injected with15 ng <i>Pif-Rel</i> dsRNA 3 or 6 days respectively. …”

Decreased motor coordination deficits in <i>Cln6^nclf</i> mice. by Jeremy P. Morgan (479017)

Neutrophil activation and recruitment and CXCR2 expression were decreased in antibiotic pre-treated mice. by Koji Watanabe (205444)

Ethanol intoxication combined with burn injury decreases miRNA155 expression in T cells. by Xiaoling Li (129705)

Decreased proliferation and increased apoptosis in <i>Mab21l2</i> mutant embryos. by Yohei Saito (180130)

“…Scale bars represent 100 µm (A, D, H, K) and 50 µm (N and P). (R) Quantitative RT-PCR for genes regulating cell proliferation and apoptosis (<i>N-myc</i>, <i>Id2</i>, <i>Cyclin D1</i>, <i>Cyclin D2</i>), marker genes of myocardial differentiation (<i>Anf</i>, <i>Chisel</i>, <i>Mlc2v</i>), genes essential for the development of the trabecular myocardium (<i>Erbb2</i>, <i>Erbb4</i>, <i>Bmp10</i>), genes essential for heart development (<i>Nkx2.5</i>, <i>Gata4</i>), and endocardial transcripts (<i>Flk1</i>, <i>Tie1</i>, <i>Tie2</i>) normalized to <i>Gapdh</i> expression using RNA from dissected hearts of E11.5 WT and <i>Mab21l2</i> mutant (−/−) embryos. …”

Rabankyrin-5 Overexpression Increases, whereas Knock-Down Decreases Fluid-Phase Uptake, Specifically by Carsten Schnatwinkel (48)

B-RAF inhibitor PLX4720 decreased hERG currents in rhabdomyosarcoma RD cells. by Tatsiana Pakladok (311653)

FG-2216 decreased plasma markers of cardiac injury in Nx-Ob-ZSF1 rats. by Pierre E. Signore (11218497)

ApoE3 decreases Rho activity and F-actin stress fibers in human VSMCs. by Bernadette Y. Hsu (753458)

miR-200c decreases KLOTHO expression in HK-2 cells by translational repression. by Kenichi Morii (6843554)

PADK decreases intra- and extracellular 6E10 staining in APPswe/PS1ΔE9 (APP-PS1) mice of 20–22 months. by David Butler (349975)

Small RNR subunit interaction with Ydj1 is decreased in Ssa3 and Ssa4 cells. by Laura E. Knighton (5991239)