Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Overexpression of TNFAIP9 remitted the renal inflammation caused by 5/6 Nx in C57 mice. by Ying Chen (9697)

Structure of P-YOLOv5s-GRNF. by Zhongjian Xie (4633099)

Overexpression of TNFAIP9 counteracted the renal damage caused by 5/6 Nx in C57 mice. by Ying Chen (9697)

An Improved Genome Assembly of Azadirachta indica A. Juss. by Binay Panda (768771)

“…The updated genome assembly (v2.0) yielded 3- and 3.5-fold increase in N50 and N75, respectively; 2.6-fold decrease in the total number of scaffolds; 1.25-fold increase in the number of valid transcriptome alignments; 13.4-fold less mis-assembly and 1.85-fold increase in the percentage repeat, over the earlier assembly (v1.0). …”

Maternal consumption of green tea extract during pregnancy and lactation alters offspring's metabolism in rats - Fig 4 by Ana C. L. Hachul (5533091)

Fig 5 - by Jacob C. Jentzer (4746999)

Mean and standard deviation of vascular density. by Beatriz Cordon (9745619)

Mean and standard deviation of vascular density. by Beatriz Cordon (9745619)

Mean and standard deviation of vascular density. by Beatriz Cordon (9745619)

Mean and standard deviation of vascular density. by Beatriz Cordon (9745619)

Effect of NAT1 knockout on cell growth in normal and low glucose. by LiLi Wang (1582915)

Table1_Loss-of-function N178T variant of the human P2Y4 receptor is associated with decreased severity of coronary artery disease and improved glucose homeostasis.DOCX by Michael Horckmans (14206388)

“…Regarding fasting plasma parameters, the N178T variant was associated with a lower concentration of glucose. …”

Trabectedin induced apoptosis in a dose-dependent manner as measured by the Muse™ Annexin V and Dead Cell assay. by Eda Acikgoz (816259)

“…After incubation time cells were collected and the phosphatydilserine externalization was evaluated using Annexin V protocol as describe. Based on Annexin V reactivity and the intensity of the 7-AAD fluorescence, cells can be classified into four categories: dead, live, early apoptosis and late apoptosis/dead. …”

Effects of FCCP and verapamil on MMP of HCT15 and CT26 cancer cells. by Jin Won Park (2901029)

Antibody IC₅₀ (or pIC₅₀) and maximum neutralization of D614G and BA.1 pseudoviruses bearing different glycosylation and SARS-CoV-2 VLPs. by Sabrina Lusvarghi (2329267)

Frequency of the number of peaks (<i>N</i>_pics) (black, left vertical axis) and average amplitude of pics (<i>A</i>_pics) (red, right vertical axis) observed i... by Sławomir Grzegorczyn (12035398)

Mean-difference plots by country: Countries with decreased variance and no change in mean height (95% confidence interval shaded). by Jewel Gausman (5210969)

Mean-difference plots by country: Countries with decreased variance and increased mean height (95% confidence interval shaded). by Jewel Gausman (5210969)