H2B depletion in the germline causes sterility of <i>C</i>. <i>elegans</i>. by Ruixue Zhao (2744689)

P8, but not the p8m mutant peptide, represses KSHV lytic reactivation. by Shaowei Wang (490684)

The <i>unc-85</i> mutation reduces chromatin H3. by Ruixue Zhao (2744689)

Targeting of Vps34 or Atg14, but not Uvrag, in Tregs reduces tumor growth in mouse models. by Erienne G. Norton (9612079)

Data_Sheet_1_Variations in the SDN Loop of Class A Beta-Lactamases: A Study of the Molecular Mechanism of BlaC (Mycobacterium tuberculosis) to Alter the Stability and Catalytic Act... by Sourya Bhattacharya (8441028)

“…To understand the molecular reasoning behind the unavailability of such mutation in real life, we have used circular dichroism (CD) spectroscopy, differential scanning calorimetry (DSC), molecular dynamics (MD) simulation, and stability-based enzyme activity to compare the stability and dynamic behaviors of native and S130G/A mutant form of BlaC. A significant decrease in melting temperature (BlaC T_M 60°C, S130A T_M 50°C, and S130G T_M 45°C), kinetic instability at higher temperature, and comparative dynamic instability correlate the fact that resistance to beta-lactam/beta-lactamase inhibitor combinations will likely not arise from the structural alteration of BlaC, therefore establishing confidence that this therapeutic modality can be potentially applied as a part of a successful treatment regimen against M. tuberculosis.…”

Data_Sheet_2_Variations in the SDN Loop of Class A Beta-Lactamases: A Study of the Molecular Mechanism of BlaC (Mycobacterium tuberculosis) to Alter the Stability and Catalytic Act... by Sourya Bhattacharya (8441028)

“…To understand the molecular reasoning behind the unavailability of such mutation in real life, we have used circular dichroism (CD) spectroscopy, differential scanning calorimetry (DSC), molecular dynamics (MD) simulation, and stability-based enzyme activity to compare the stability and dynamic behaviors of native and S130G/A mutant form of BlaC. A significant decrease in melting temperature (BlaC T_M 60°C, S130A T_M 50°C, and S130G T_M 45°C), kinetic instability at higher temperature, and comparative dynamic instability correlate the fact that resistance to beta-lactam/beta-lactamase inhibitor combinations will likely not arise from the structural alteration of BlaC, therefore establishing confidence that this therapeutic modality can be potentially applied as a part of a successful treatment regimen against M. tuberculosis.…”

Table_1_A Stimulatory Role for Cytokinin in the Arbuscular Mycorrhizal Symbiosis of Pea.DOCX by Dane M. Goh (6446381)

Image_1_A Stimulatory Role for Cytokinin in the Arbuscular Mycorrhizal Symbiosis of Pea.JPEG by Dane M. Goh (6446381)

Test apparatus. by Sara Hintze (3216885)

Evaluation of whole wheat flour sourdough as a promising ingredient in short dough biscuits by Tuba ALIOĞLU (10464668)

“…The incorporation of WWF on dough formulation increased both G' and G” moduli, while the inclusion of WWF by sourdough fermentation caused a significant reduction. Spread ratio of the biscuits decreased as the WWF ratio in the formulation increased (p < 0.05). …”

Vps34 supports Treg maintenance in lymphoid and non-lymphoid tissues. by Erienne G. Norton (9612079)

“…GSEA enrichment plots showing increased cTreg signature (left; i.e., top 200 upregulated genes [log₂FC > 0.5, FDR < 0.05] in cTregs versus eTregs) and decreased eTreg signature (right; i.e., top 200 upregulated genes [log₂FC > 0.5, FDR < 0.05] in eTregs versus cTregs) in CD45.2⁺ Tregs from <i>Foxp3</i>^Cre<i>Pik3c3</i>^fl/fl mixed BM chimera mice compared to control mixed BM chimera mice. …”

The contacts analysis between the CL molecule and SVA 3C^pro by LigPlot⁺. by Hai-Fan Zhao (15990862)

Panx1^-/- mice present with a reduction in the number of alveoli during early lactation. by Michael K. G. Stewart (591711)

“…Values are means ± SEM. N = 6. Scale bars = 50 um.</p>…”

Impact of different substitution rate category parameters on cluster inference in different mixture datasets. by August Guang (9975678)

Brain transition cost correlates with task demand and performance. by Giacomo Barzon (19832364)

Comparison between mean-field solutions and simulations on networks. by Valeria d’Andrea (12095838)

Representative phase contrast images of human cornea epithelial cell (HCE-T). by Ning Chai (394956)

GDNF-mediated cancer cell migration and a DRG co-culture model of PNI. by Richard L. Bakst (317552)

“…<p>A. MiaPaCa2 pancreatic cancer cells were (**) grown in a culture insert adjacent to a DRG (*) in Matrigel. …”

ACY-1083 improves the epithelial integrity in fully differentiated HBEC ALI cultures challenged with different barrier disruptors. by Jenny Horndahl (10478701)

mRNA and protein expression of VIM, TPI and MAT2A in native cells. by Christina Herre (12475755)

“…</b> Western blot analysis of VIM, TPI and MAT2A in native cells of HD1 and HD2 at day 5, 15, 25 and 50. …”