ATP Induced Brain-Derived Neurotrophic Factor Expression and Release from Osteoarthritis Synovial Fibroblasts Is Mediated by Purinergic Receptor P2X4 by Kerstin Klein (161627)

“…Endogenous P2X4 expression was decreased by siRNA transfection before ATP stimulation. …”

Graphical summary of the reGenotyper algorithm. by Konrad Zych (2264593)

“…Then we re-map the QTLs using the perturbed genotype data and unchanged phenotype matrix and observe that for most of the QTL the significance decreases (dark color changes to light color), i.e. the QTL loses significance if noise is added. 3) Correction of wrong genotypes. …”

<b>Bleomycin-induced lung fibrosis and dysfunction is exacerbated by G6PD deficiency</b> by Sachin Gupte (8211615)

“…In the present study, our objective was to determine altered metabolic pathways that contribute to Bleomycin sulfate (BLM; 5 mg/kg)-induced PF in rats. We determined the effects of nebulized BLM on PF in CRISPR-edited rats expressing glucose-6-phosphate dehydrogenase (G6PD) variant (S188F; G6PD^S188F) and their wild-type (WT) littermates. …”

Data_Sheet_1_GPR171 Agonist Reduces Chronic Neuropathic and Inflammatory Pain in Male, But Not Female Mice.docx by Akila Ram (6842501)

“…GPR171 is a promising therapeutic target that is widely expressed through the brain, including within the descending pain modulatory regions. Here, we explore the therapeutic potential of the GPR171 agonist, MS15203, in its ability to alleviate chronic pain in male and female mice using a once-daily systemic dose (10 mg/kg, i.p.) of MS15203 over the course of 5 days. …”

Table_1_Inhaled Nitric Oxide Treatment for Aneurysmal SAH Patients With Delayed Cerebral Ischemia.DOCX by Christian Fung (289402)

“…The response to iNO was considered positive if: cerebral artery diameter increased by 10% in digital subtraction angiography (DSA), or tissue oxygen partial pressure (PtiO₂) increased by > 5 mmHg, or transcranial doppler (TCD) values decreased more than 30 cm/sec, or mean transit time (MTT) decreased below 6.5 secs in CT perfusion (CTP). …”

Supplementary Material for: Temporary Trends in Fever following Transcatheter Aortic Valve Implantation by Witberg G. (4159936)

“…The frequency decreased gradually and significantly across timeframes (32.8, 23.6, and 14.5%, respectively, <i>p</i> < 0.001)<i>.…”

Parameterizing the cortical state based on avalanche distributions. by Leila Fakhraei (4002038)

“…<p>For both the experiment (a-c) and the model (d-f), we indexed the continuum of observed cortical states based on the prevalence of different spatiotemporal scales of activity. …”

Structure-Based Analysis of A19D, a Variant of Transthyretin Involved in Familial Amyloid Cardiomyopathy by Priscila Ferreira (498747)

“…As far as we know, this is the first description of a non-V30M mutation in Brazil. …”

CSF N-Glycan Profiles to Investigate Biomarkers in Brain Developmental Disorders: Application to Leukodystrophies Related to eIF2B Mutations by Anne Fogli (138515)

“…We found in control CSF that tri-antennary/bisecting and high mannose structures were highly represented in samples obtained between 1 to 5 years of age, whereas fucosylated, sialylated structures were predominant at later age. …”

Green Synthesis of Upconverting NaYF4 and NaGdF4 Materials and Energy Levels Determination by Luidgi Giordano (10738753)

“…The bandgaps of undoped NaGdF4 and NaYF4 were measured using synchrotron radiation vacuum-UV (VUV) diffuse reflectance, with values of 10.20 eV for the cubic phase and 10.80 eV for the hexagonal phase for both materials. …”

<i>S</i>. <i>mediterranea</i> cathepsin protease mRNA is reduced after starvation while dsRNA treatment with SmedCB is specific to cathepsin B. by Louise S. Goupil (2922159)

“…Starved worms demonstrated a 65–75% reduction in cathepsin B mRNA levels and 50–65% reduction in cathepsin D mRNA. …”

Supplementary file 1_Synergistic effects of potassium and gibberellin on the yield and quality of yellow pitahaya (Hylocereus megalanthus) fruits in the Peruvian Amazon.docx by Julio Cesar Santos-Pelaez (22674113)

“…This research evaluated the combined effect of potassium (K₂O) and gibberellic acid (GA₃) on yield and fruit quality in field-grown pitahaya in the Peruvian Amazon using a 4 × 2 factorial randomized block design with four potassium doses (0, 50, 100, 150 kg ha⁻¹) and two GA₃ levels (0 and 50 mg L⁻¹). …”

Size of Markov networks of AMR surveillance data (<i>m</i>) over L₁ regularization values. by William J. Love (3350027)

“…The solid line represents the median graph size (<i>m</i>₅₀) for the set <i>R</i>, which contains one R-net for each of the 9 years in the study at each evaluated value of <i>ρ</i>, and the dashed lines above and below <i>m</i>₅₀ represent the maximum and minimum size of <i>R</i>, respectively. …”

Effect of Alpinia zerumbet essential oil on the shelf life of tambaqui fillets during short-term refrigerator storage by Ana Karolinne Anastacio de SOUSA (6673673)

“…The treatments were A. zerumbet essential oil at 0.75% v v-1 (AEO 0.75%), A. zerumbet essential oil at 1.5% v v-1 (AEO 1.5%) and a control (no essential oil). …”

DNA epitope vaccine improves acquisition and retention of spatial memory in immune mice. by Nina Movsesyan (86328)

“…<p>A) The escape latency to reach the platform was significantly decreased in the groups of non-transgenic (n = 6) and 3xTg-AD immune mice (n = 9) versus age-matched groups of MDC-irrelevant control (n = 5) and non-vaccinated control 3xTg-AD mice (n = 5). …”

Targeting Anticancer Drug Delivery to Pancreatic Cancer Cells Using a Fucose-Bound Nanoparticle Approach by Makoto Yoshida (151742)

“…Excess L-fucose decreased the efficiency of Cy5.5 introduction by L-fucose-bound liposomes, suggesting L-fucose-receptor-mediated delivery. …”

Altered MM BM-MSC hematopoietic support and immunomodulatory capacity. by Thibaud André (392611)

“…T cell proliferation was assessed by BrdU incorporation assay after 5 days of co-culture. For each ratio, MM BM-MSCs had decreased inhibition capacity. …”

Can handling a weapon make soldiers more unstable? by L. Eduardo Cofré Lizama (14095293)

“…This study determined the effects of weapon handling and speed on gait stability in seventeen soldiers walking on a treadmill with and without a replica weapon at self-selected (SS), 3.5 km·h⁻¹, 5.5 km·h⁻¹, and 6.5 km·h⁻¹ while carrying a 23-kg load. …”

Investigating sperm selection in Y-shredding strains. by Matteo Vitale (13130647)

“…We found no significant differences in the ratio of Y-bearing and nSC sperm between the testes and spermathecae in this strain. n Te = 5, n Sp = 5. …”

Sialidase activity assay upon oseltamivir treatment <i>in vitro</i>. by Joana T. de Oliveira (718565)