Hybridsampling triple size models performance. by Anna Beatriz Silva (20989245)

“…We evaluate five data balancing techniques: Undersampling, Oversampling, and three Hybridsampling configurations where the minority class was increased by factors 2, 3, and 4. …”

Bilayer Structure and Lipid Dynamics in a Model Stratum Corneum with Oleic Acid by Matthew I. Hoopes (1738276)

“…Importantly, cholesterol and other species diffuse faster when radial densities indicate nearest neighbors include more cholesterol. We also find that, with the addition of oleic acid, the bilayer midplane and interfacial densities are reduced and there is a 3% decrease in total thickness occurring mostly near the hydrophilic interface at 300 K with reduced overall density at 340 K. …”

Bilayer Structure and Lipid Dynamics in a Model Stratum Corneum with Oleic Acid by Matthew I. Hoopes (1738276)

“…Importantly, cholesterol and other species diffuse faster when radial densities indicate nearest neighbors include more cholesterol. We also find that, with the addition of oleic acid, the bilayer midplane and interfacial densities are reduced and there is a 3% decrease in total thickness occurring mostly near the hydrophilic interface at 300 K with reduced overall density at 340 K. …”

DHPG-induced long-term depression is not dependent on protein synthesis or mammalian Target of Rapamycin in <i>Cyfip1</i> heterozygotes. by Ozlem Bozdagi (144573)

“…<p>(<b>A</b>) LTD was induced by DHPG (50 µM for 5 minutes, indicated by the short horizontal bar) in hippocampal slices from wildtype (Wt) and <i>Cyfip1</i> heterozygous (Het) mice. …”

Lifespan analysis of <i>C. elegans</i> strains in the presence of TCA cycle intermediates. by Clare B. Edwards (385682)

“…<p>10 mM concentrations of malate, succinate, or fumarate were present where indicated. (<b>A</b>) Malate (log-rank <i>p</i><0.001) or fumarate (log-rank <i>p</i><0.001), but not succinate (log-rank <i>p</i> = 0.72) extended lifespan of N2 worms. …”

mycHIF3α reduces the number of Clara cells. by Yadi Huang (381866)

“…<p>The expression of the Clara cell marker, Ccsp, was strongly decreased in mycHIF3α transgenic lungs at gestational age E18.5 compared to controls (A and C versus B and D). …”

Clinical and epidemiological study in patients with primary open-angle glaucoma by Luciana dos Mares Guia Ribeiro (4985879)

“…A minority of participants present risk factors such as high myopia (6.3%) and diabetes mellitus (17.9%). …”

Data Sheet 1_HLA class, calcineurin inhibitor levels, and the risk of graft failure in kidney recipients with de novo donor-specific antibodies.pdf by Marc-Antoine Béland (20294229)

“…Additionally, the risk of graft loss decreased with increasing CNI trough levels following dnDSA detection (aHR 0.7 [0.6-0.9] for each increase in 1 ng/mL, p=0.02).…”

Data Sheet 2_HLA class, calcineurin inhibitor levels, and the risk of graft failure in kidney recipients with de novo donor-specific antibodies.pdf by Marc-Antoine Béland (20294229)

“…Additionally, the risk of graft loss decreased with increasing CNI trough levels following dnDSA detection (aHR 0.7 [0.6-0.9] for each increase in 1 ng/mL, p=0.02).…”

Androgen Receptor Functional Analyses by High Throughput Imaging: Determination of Ligand, Cell Cycle, and Mutation-Specific Effects by Adam T. Szafran (269691)

“…</p><h3>Methodology/Principal Findings</h3><p>We report the development of a high throughput (HT) image-based assay that quantifies AR subcellular and subnuclear distribution, and transcriptional reporter gene activity on a cell-by-cell basis. …”

Inhibition of CCL28/CCR10-mediated eNOS Downregulation Improves Skin Wound Healing in the Obesity-induced Mouse Model of Type 2 Diabetes by Zhenlong Chen (342867)

The effect of sample size on p-values and rank order for the top 100 transcripts. by Cynthia Stretch (586403)

“…<p>For each n tested (n = 10 (5♀, 5♂), 30 (15♀, 15♂), 60 (30♀, 30♂), 90 (45♀, 45♂) and 120 (60♀, 60♂) are shown here), n samples were randomly selected from our dataset of n = 134 subjects, 50 different times. …”

Different Origins of Gamma Rhythm and High-Gamma Activity in Macaque Visual Cortex by Supratim Ray (224895)

“…Because gamma power and spiking activity tend to co-vary during most stimulus manipulations (such as contrast modulations) or cognitive tasks (such as attentional modulation), it is difficult to dissociate these two hypotheses. We studied the relationship between high-gamma power, gamma rhythm, and spiking activity in the primary visual cortex (V1) of awake monkeys while varying the stimulus size, which increased the gamma power but decreased the firing rate, permitting a dissociation. …”

Opening of Astrocytic Mitochondrial ATP-Sensitive Potassium Channels Upregulates Electrical Coupling between Hippocampal Astrocytes in Rat Brain Slices by Jiangping Wang (281901)

“…Activation of mitoK_ATP channel also decreased the latency time of the transjunctional currents by 50%. …”

Table_1_Risk and Prognosis of Secondary Rectal Cancer After Radiation Therapy for Pelvic Cancer.docx by Runkun Yang (6079922)

“…Primary cancers were located in the prostate (50.83%), bladder (24.18%), corpus uterus (16.26%), cervix (5.83%), and ovary (2.91%). …”

DataSheet1_The Relationship Between Low-Density Lipoprotein Cholesterol and Progression of Mild Cognitive Impairment: The Influence of rs6859 in PVRL2.docx by Qianyi Xiao (3987308)

“…This study aims to investigate the effects of cholesterol and genetic risk factors on progression of mild cognitive impairment (MCI) to AD.</p><p>Methods: We prospectively followed 316 MCI participants aged ≥50 years with a baseline cholesterol profile and SNP genotyping data for 4.5 years on average in a sub-cohort of the Shanghai Aging Study. …”

Table_1_Effect and Safety of Adding Metformin to Insulin Therapy in Treating Adolescents With Type 1 Diabetes Mellitus: An Updated Meta-Analysis of 10 Randomized Controlled Trials.... by Ying Liu (18461)

“…Results suggested that metformin significantly decreased the HbA1c level at 12 months (mean difference [MD])=-0.50, 95% confidence interval [CI]=-0.61 to -0.39, P < 0.01); BMI (kg/m²) at 3 months (MD=-1.05, 95%CI=-2.05 to -0.05, P=0.04); BMI z-score at 6 months (MD=-0.10, 95%CI=-0.14 to -0.06, P<0.01); and TIDD at 3 (MD=-0.13, 95%CI=-0.20 to -0.06, P<0.01), 6 (MD=-0.18, 95%CI=-0.25 to -0.11, P<0.01), and 12 (MD=-0.42, 95%CI=-0.49 to -0.35, P<0.01) months but significantly increased the risk of hypoglycemia events (risk ratio [RR]=3.13, 95%CI=1.05 to 9.32, P=0.04) and GIAEs (RR=1.64, 95%CI=1.28 to 2.10, P<0.01). …”

Table_2_Effect and Safety of Adding Metformin to Insulin Therapy in Treating Adolescents With Type 1 Diabetes Mellitus: An Updated Meta-Analysis of 10 Randomized Controlled Trials.... by Ying Liu (18461)

“…Results suggested that metformin significantly decreased the HbA1c level at 12 months (mean difference [MD])=-0.50, 95% confidence interval [CI]=-0.61 to -0.39, P < 0.01); BMI (kg/m²) at 3 months (MD=-1.05, 95%CI=-2.05 to -0.05, P=0.04); BMI z-score at 6 months (MD=-0.10, 95%CI=-0.14 to -0.06, P<0.01); and TIDD at 3 (MD=-0.13, 95%CI=-0.20 to -0.06, P<0.01), 6 (MD=-0.18, 95%CI=-0.25 to -0.11, P<0.01), and 12 (MD=-0.42, 95%CI=-0.49 to -0.35, P<0.01) months but significantly increased the risk of hypoglycemia events (risk ratio [RR]=3.13, 95%CI=1.05 to 9.32, P=0.04) and GIAEs (RR=1.64, 95%CI=1.28 to 2.10, P<0.01). …”

Unfolded protein response is activated by DHB. by Dahai Yu (394130)

“…<p>(A) DHB incubation for 24 h significantly decreased ATF-6 (~90 kDa) expression and proportionally increased cleaved ATF-6 (~50 kDa) expression. …”

Zebrafish Caudal Fin Angiogenesis Assay—Advanced Quantitative Assessment Including 3-Way Correlative Microscopy - Fig 4 by Ruslan Hlushchuk (56116)

“…<p><b>DAA: Assessment of the anti-angiogenic effects of PTK787 at different concentrations 50, 100, 250, 500 nM: a-c</b> Fluorescent images of regenerating caudal fins at 3 (<b>a</b>^<b>1</b><b>-c</b>^<b>1</b>), 5 (<b>a</b>^<b>2</b><b>-c</b>^<b>2</b>) and 7 dpa (<b>a</b>^<b>3</b><b>-c</b>^<b>3</b>) under 3 different conditions: vehicle control (left column), 100 nM (middle) and 500 nM PTK787 (right column). …”