Image1_Modification of Fibronectin by Non-Enzymatic Glycation Impairs K+ Channel Function in Rat Cerebral Artery Smooth Muscle Cells.JPEG by Yan Yang (33204)

“…Bovine FN (1 mg/ml) was glycated (gFN) for 5 days using methylglyoxal (50 mM), and albumin was similarly glycated as a non-matrix protein control. …”

Image_1_Modest Gains After an 8-Week Exercise Program Correlate With Reductions in Non-traditional Markers of Cardiovascular Risk.pdf by Grace Liang (4398046)

“…</p><p>Conclusion: Modest improvements in physical fitness, physical activity, and/or weight loss through a short-term exercise program was associated with decreased plasma levels of plasminogen activator inhibitor, platelet derived growth factor beta, and angiopoietin, which have been associated with impaired fibrinolysis and inflammation.…”

Data Sheet 3_The novel pleuromutilin derivative 22–((4-((4-nitrophenyl)acetamido)phenyl)thio)deoxy pleuromutilin possesses robust anti-mycoplasma activity both in vitro and in vivo... by Xirui Xia (12075476)

“…</p>Results<p>The results show that compound 16C has low toxicity (LD₅₀ > 5,000 mg/kg). Its pharmacokinetic profile is characterized by a short time to maximum concentration (Tmax = 0.24 h), high bioavailability (F = 71.29%), and short elimination half-life (T_1/2kel) (intramuscular and intravenous administration was 2.20 and 1.89 h, respectively). …”

Data Sheet 1_The effect of vagus nerve stimulation on heart rate and respiration rate and their impact on seizure susceptibility in anaesthetized rats under pentylenetetrazol.pdf by Javier Chávez Cerda (20913026)

“…Additionally, the latency of the seizures was longer in the sham VNS (291.5 ± 84.4 s) compared to standard VNS (200.5 ± 59.5 s) and breathing-synchronized VNS (206.9 ± 66.0 s), meaning that the seizures under stimulation were starting earlier. …”

table_4_B Cell-Related Circulating MicroRNAs With the Potential Value of Biomarkers in the Differential Diagnosis, and Distinguishment Between the Disease Activity and Lupus Nephri... by Huidi Zhang (716813)

“…We then investigated the relationship between expressions of the selected miRNAs and SLE clinical indicators. As a result, 14 miRNAs (miR-103, miR-150, miR-20a, miR-223, miR-27a, miR-15b, miR-16, miR-181a, miR-19b, miR-22, miR-23a, miR-25, miR-92a, and miR-93) were significantly decreased in the plasma of SLE patients compared with healthy controls (P < 0.05) and could act as the diagnostic signature to distinguish SLE patients from healthy donors. …”

table_3_B Cell-Related Circulating MicroRNAs With the Potential Value of Biomarkers in the Differential Diagnosis, and Distinguishment Between the Disease Activity and Lupus Nephri... by Huidi Zhang (716813)

“…We then investigated the relationship between expressions of the selected miRNAs and SLE clinical indicators. As a result, 14 miRNAs (miR-103, miR-150, miR-20a, miR-223, miR-27a, miR-15b, miR-16, miR-181a, miR-19b, miR-22, miR-23a, miR-25, miR-92a, and miR-93) were significantly decreased in the plasma of SLE patients compared with healthy controls (P < 0.05) and could act as the diagnostic signature to distinguish SLE patients from healthy donors. …”

table_1_B Cell-Related Circulating MicroRNAs With the Potential Value of Biomarkers in the Differential Diagnosis, and Distinguishment Between the Disease Activity and Lupus Nephri... by Huidi Zhang (716813)

“…We then investigated the relationship between expressions of the selected miRNAs and SLE clinical indicators. As a result, 14 miRNAs (miR-103, miR-150, miR-20a, miR-223, miR-27a, miR-15b, miR-16, miR-181a, miR-19b, miR-22, miR-23a, miR-25, miR-92a, and miR-93) were significantly decreased in the plasma of SLE patients compared with healthy controls (P < 0.05) and could act as the diagnostic signature to distinguish SLE patients from healthy donors. …”

Data_Sheet_1_Pilot Study on Quantitative Cervical Cord and Muscular MRI in Spinal Muscular Atrophy: Promising Biomarkers of Disease Evolution and Treatment?.pdf by Giovanni Savini (510997)

“…Average muscle FF was already high at baseline (50%) and progressed over time (57%). w-T2 was also slightly higher than previously published data at baseline and slightly decreased over time. …”

table_5_B Cell-Related Circulating MicroRNAs With the Potential Value of Biomarkers in the Differential Diagnosis, and Distinguishment Between the Disease Activity and Lupus Nephri... by Huidi Zhang (716813)

“…We then investigated the relationship between expressions of the selected miRNAs and SLE clinical indicators. As a result, 14 miRNAs (miR-103, miR-150, miR-20a, miR-223, miR-27a, miR-15b, miR-16, miR-181a, miR-19b, miR-22, miR-23a, miR-25, miR-92a, and miR-93) were significantly decreased in the plasma of SLE patients compared with healthy controls (P < 0.05) and could act as the diagnostic signature to distinguish SLE patients from healthy donors. …”

table_2_B Cell-Related Circulating MicroRNAs With the Potential Value of Biomarkers in the Differential Diagnosis, and Distinguishment Between the Disease Activity and Lupus Nephri... by Huidi Zhang (716813)

“…We then investigated the relationship between expressions of the selected miRNAs and SLE clinical indicators. As a result, 14 miRNAs (miR-103, miR-150, miR-20a, miR-223, miR-27a, miR-15b, miR-16, miR-181a, miR-19b, miR-22, miR-23a, miR-25, miR-92a, and miR-93) were significantly decreased in the plasma of SLE patients compared with healthy controls (P < 0.05) and could act as the diagnostic signature to distinguish SLE patients from healthy donors. …”

Visualization of the baseline (WT) and <i>Tsc1</i> null (KO) results within a smooth muscle cell phenotypic space bounded by vertices defined as purely contractile (1.0), purely sy... by Ana C. Estrada (8917370)

Investigation Into the Effects of Non-Linear Loading of Domestic Power Network on Home Appliances by Hossain, Ajad

“…Single-phase IM behavior when pure sine wave is applied. Supply from a single-phase Inverter with Fundamental frequency (50 Hz) only: Fig. 5. …”
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Negative regulation of protein-coding genes suggests increased genomic auto-immunity of <i>D</i>. <i>simulans</i> alleles. by Luyang Wang (476973)

“…<p>(A) The number of genes whose expression levels are decreased/increased (>1.5 fold, blue/red) in the presence of each transgene as compared to the corresponding mutant. …”

Table1_Effectiveness of early heparin therapy on outcomes in critically ill patients with sepsis-induced coagulopathy.docx by Jia-Jia Huang (243641)

“…Further analysis showed that treatment with 6,250–13750 IU/day of unfractionated heparin associated with a decreased risk of intensive care unit mortality. …”

Table 1_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx by Chao Lv (335727)

“…Ultra-high-performance liquid chromatography-quadrupole orbitrap mass spectrometry (UHPLC-QTOF-MS) was used to identify the metabolites in TFA. MAFLD mice induced by a high-fat diet were treated with TFA at doses of 50 and 100 mg/kg. …”

Table 2_Multi-omics reveals total flavones from Abelmoschus manihot (L.) Medik. [Malvaceae] ameliorate MAFLD via PI3K/AKT/mTOR-mediated autophagy.docx by Chao Lv (335727)

“…Ultra-high-performance liquid chromatography-quadrupole orbitrap mass spectrometry (UHPLC-QTOF-MS) was used to identify the metabolites in TFA. MAFLD mice induced by a high-fat diet were treated with TFA at doses of 50 and 100 mg/kg. …”

Supplemental Material by LIN LEI (10997319)

“…First, hepatocytes were cultured with various concentrations of NEFA (0, 0.6, 1.2, or 2.4 m<em>M</em>) for 12 h. In a second experiment, hepatocytes were treated with AdipoRon at different concentrations (0, 5, 25, or 50 μ<em>M</em> for 12 h) and times (25 μ<em>M</em> AdipoRon for 0, 6, 12, or 24 h) with or without NEFA (1.2 m<em>M</em>) treatment. …”

Enhanced Immunosuppressive Capability of Mesenchymal Stem Cell-derived Small Extracellular Vesicles with High Expression of CD73 in Experimental Autoimmune Uveitis by yanan duan (18420690)

“…Treatment with sEVs-CD73 results in a decreased proportion of Th1 cells in the spleen, draining lymph nodes, and eyes, accompanied by an increased proportion of regulatory T-cells (Treg cells). …”

Presentation1_Differential lipid signaling from CD4+ and CD8+ T cells contributes to type 1 diabetes development.pptx by Tayleur D. White (19690648)

“…Introduction<p>We reported that Ca²⁺-independent phospholipase A₂β (iPLA₂β)–derived lipids (iDLs) contribute to type 1 diabetes (T1D) onset. …”

Reproducibility of quantitative coronary computed tomography angiography in asymptomatic individuals and patients with acute chest pain by Martina C. de Knegt (6086756)

“…Reproducibility of plaque composition decreased with decreasing plaque density (intraobserver and interobserver CCC for dense calcium (>0.99; 0.98), fibrotic (0.96; 0.93), fibro-fatty (0.95; 0.91), and necrotic core tissue (0.89; 0.84). …”