Endothelial CRIF1 deletion elevated inflammatory cytokine and VCAM-1 expression <i>in vivo</i> and <i>in vitro</i>. by Shuyu Piao (4731327)

Membrane Perturbations and Assay Interferences by Ivermectin Explain Its In Vitro SARS-CoV‑2 Antiviral Activities and Lack of Translatability by Richard T. Eastman (6051881)

“…Furthermore, at the low micromolar concentrations where ivermectin reduced SARS-CoV-2 viral burden in vitro, ivermectin decreased cell viability, modified membrane bilayer properties, and nonspecifically dysregulated membrane protein functions. …”

Membrane Perturbations and Assay Interferences by Ivermectin Explain Its In Vitro SARS-CoV‑2 Antiviral Activities and Lack of Translatability by Richard T. Eastman (6051881)

“…Furthermore, at the low micromolar concentrations where ivermectin reduced SARS-CoV-2 viral burden in vitro, ivermectin decreased cell viability, modified membrane bilayer properties, and nonspecifically dysregulated membrane protein functions. …”

Membrane Perturbations and Assay Interferences by Ivermectin Explain Its In Vitro SARS-CoV‑2 Antiviral Activities and Lack of Translatability by Richard T. Eastman (6051881)

“…Furthermore, at the low micromolar concentrations where ivermectin reduced SARS-CoV-2 viral burden in vitro, ivermectin decreased cell viability, modified membrane bilayer properties, and nonspecifically dysregulated membrane protein functions. …”

Image_5_Global Profiling of Lysine Acetylation in Borrelia burgdorferi B31 Reveals Its Role in Central Metabolism.pdf by Sébastien Bontemps-Gallo (2941824)

“…Using specific enzymatic assays, we were able to demonstrate that hyperacetylation of proteins in S phase appeared to play a role in decreasing the enzymatic activity of at least two glycolytic proteins. …”

Table_5_Profiling the Course of Resolving vs. Persistent Inflammation in Human Monocytes: The Role of IL-1 Family Molecules.XLSX by Paola Italiani (519267)

Image_5_Blockade of TRPC Channels Limits Cholinergic-Driven Hyperexcitability and Seizure Susceptibility After Traumatic Brain Injury.TIF by Chase M. Carver (4597711)

“…We found region-specific increases in expression of TRPC1, TRPC4, and TRPC5 subunits in the hippocampus and cortex following TBI. …”

Image5_Long Noncoding RNA and Circular RNA Expression Profiles of Monocyte-Derived Dendritic Cells in Autoimmune Hepatitis.TIF by Fan Yang (1413)

Table_5_Probiotic Consortia: Reshaping the Rhizospheric Microbiome and Its Role in Suppressing Root-Rot Disease of Panax notoginseng.DOCX by Jinhao Zhang (6630860)

DataSheet5_Refining dual RNA-seq mapping: sequential and combined approaches in host-parasitic plant dynamics.csv by Carmine Fruggiero (20143830)

Video_5_Hearing Someone Laugh and Seeing Someone Yawn: Modality-Specific Contagion of Laughter and Yawning in the Absence of Others.WMV by Micaela De Weck (12098282)

Image_5_A Discovery of a Genetic Mutation Causing Reduction of Atrogin-1 Expression in Broiler Chicken Muscle.tif by Jinxiu Li (221935)

DataSheet2_Trametes robiniophila Murr Sensitizes Gastric Cancer Cells to 5-Fluorouracil by Modulating Tumor Microenvironment.zip by Jing-Li Xu (12553285)

“…We observed that the combination of TRMBE and 5-FU decreased the risk of liver metastasis in vivo. …”

DataSheet1_Trametes robiniophila Murr Sensitizes Gastric Cancer Cells to 5-Fluorouracil by Modulating Tumor Microenvironment.docx by Jing-Li Xu (12553285)

“…We observed that the combination of TRMBE and 5-FU decreased the risk of liver metastasis in vivo. …”

Image_5_Combination Therapy of Mithramycin A and Immune Checkpoint Inhibitor for the Treatment of Colorectal Cancer in an Orthotopic Murine Model.tif by Rinku Dutta (2131366)

“…Tumors and spleens were analyzed by flow cytometry for the distinct immune cell populations affected by the treatment, in addition to RT-PCR for tumor samples. We demonstrated the combination treatment decreases tumor growth, thus increasing the effectiveness of the CB. …”

Rho Kinase ROCK2 Mediates Acid-Induced NADPH Oxidase NOX5-S Expression in Human Esophageal Adenocarcinoma Cells by Jie Hong (122604)

“…However, how acid upregulates NOX5-S is not well known. We found that acid-induced increase in NOX5-S expression was significantly decreased by the Rho kinase (ROCK) inhibitor Y27632 in BE mucosal biopsies and FLO-1 EA cells. …”

Data_Sheet_5_Deep Soil Layers of Drought-Exposed Forests Harbor Poorly Known Bacterial and Fungal Communities.XLSX by Beat Frey (307473)

Table_5_m6A Modification Mediates Mucosal Immune Microenvironment and Therapeutic Response in Inflammatory Bowel Disease.DOC by Yongyu Chen (8477316)

Model parameters. by Maria Chironna (2268574)

“…<div><p>Global mitigation strategies to tackle the threat posed by SARS-CoV-2 have produced a significant decrease of the severity of 2020/21 seasonal influenza, which might result in a reduced population natural immunity for the upcoming 2021/22 influenza season. …”

Data_Sheet_5_Gut microbiome changes in mouse, Mongolian gerbil, and hamster models following Clostridioides difficile challenge.PDF by Shuangshuang Wan (4014089)