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n decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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Proteasome activity was decreased in the <i>myc-rpt6-S119A</i> mutant.
Published 2017“…<p>(A) Lysates from strains in stationary phase (A<sub>600</sub>>5.0) were subjected to native gel electrophoresis followed by an in-gel activity assay with the fluorogenic proteasome substrate Suc-LLVY-AMC. …”
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263
A Functional 12T-Insertion Polymorphism in the <i>ATP1A1</i> Promoter Confers Decreased Susceptibility to Hypertension in a Male Sardinian Population
Published 2015“…To test the effects of decreased α1Na,K-ATPase expression on blood pressure, we measured blood pressure by radiotelemetry in three month-old, highly inbred heterozygous knockout <i>ATP1A1+/−</i> male mice with resultant 58% reduction in ATP1A1 protein levels. …”
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Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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266
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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267
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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268
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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269
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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270
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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271
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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272
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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273
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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274
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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275
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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276
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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277
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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278
Chloro Half-Sandwich Osmium(II) Complexes: Influence of Chelated N,N-Ligands on Hydrolysis, Guanine Binding, and Cytotoxicity
Published 2007“…Relatively little is known about the kinetics or the pharmacological potential of organometallic complexes of osmium compared to its lighter congeners, iron and ruthenium. We report the synthesis of seven new complexes, [(η<sup>6</sup>-arene)Os(NN)Cl]<sup>+</sup>, containing different bidentate nitrogen (N,N) chelators, and a dichlorido complex, [(η<sup>6</sup>-arene)Os(N)Cl<sub>2</sub>]. …”
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279
Elevated IDO activity in HD mouse brains is decreased by <i>ex-vivo</i> iron chelation.
Published 2021“…<p>Mouse pups were supplemented with carbonyl iron from postnatal days 10–17 and then were sacrificed at 14 weeks of age. <b>A.</b> Striatal IDO activity is increased in N171-82Q HD mice and significantly decreased by <i>ex vivo</i> iron (III) chelation (50 μM deferoxamine). …”
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