Data_Sheet_1_A Comparative Analysis of Reactive Müller Glia Gene Expression After Light Damage and microRNA-Depleted Müller Glia—Focus on microRNAs.pdf by Seoyoung Kang (10033280)

“…We found: (1) The vast majority of MG miRNAs declined in reactive MG 7 days after light damage. (2) Only four miRNAs increased after light damage, which included miR-124. (3) The top 10 genes found upregulated in reactive MG after light damage include Gfap, Serpina3n, Ednrb and Cxcl10. (4) The miRNA decrease in reactive MG 7 days after injury resembles the profile of Dicer-depleted MG after one month. (5) The comparison of both mRNA expression datasets (light damage and Dicer-cKO) showed 1,502 genes were expressed under both conditions, with Maff , Egr2, Gadd45b, and Atf3 as top upregulated candidates. (6) The DIANA-TarBase v.8 miRNA:RNA interaction tool showed that three miRNAs were found to be present in all networks, i.e., after light damage, and in the combined data set; these were miR-125b-5p, let-7b and let-7c. …”

Data_Sheet_2_A Comparative Analysis of Reactive Müller Glia Gene Expression After Light Damage and microRNA-Depleted Müller Glia—Focus on microRNAs.pdf by Seoyoung Kang (10033280)

“…We found: (1) The vast majority of MG miRNAs declined in reactive MG 7 days after light damage. (2) Only four miRNAs increased after light damage, which included miR-124. (3) The top 10 genes found upregulated in reactive MG after light damage include Gfap, Serpina3n, Ednrb and Cxcl10. (4) The miRNA decrease in reactive MG 7 days after injury resembles the profile of Dicer-depleted MG after one month. (5) The comparison of both mRNA expression datasets (light damage and Dicer-cKO) showed 1,502 genes were expressed under both conditions, with Maff , Egr2, Gadd45b, and Atf3 as top upregulated candidates. (6) The DIANA-TarBase v.8 miRNA:RNA interaction tool showed that three miRNAs were found to be present in all networks, i.e., after light damage, and in the combined data set; these were miR-125b-5p, let-7b and let-7c. …”

Anteriorly traveling Lfng stripes and segmentation-clock period. by Susan D. Hester (204004)

“…We increase or decrease the segmentation-clock period by varying how long we integrate the segmentation-clock ODEs during each time step; by doing so, we easily vary the clock period relative to other processes in the simulation without altering parameters within the segmentation-clock submodel or changing the clock response to FGF8, Wnt3a or Delta/Notch signaling. …”

image1_Cinical, Metabolic, and Genetic Analysis and Follow-Up of Eight Patients With HIBCH Mutations Presenting With Leigh/Leigh-Like Syndrome.tif by Junling Wang (252266)

“…The most prominent clinical manifestations were developmental regression/delay, hypotonia, encephalopathy, and feeding difficulties. We administered drug and dietary treatment. During follow-up, five patients responded positively to treatment with a significant decrease in NPMDS scores. …”

IGFBP-3 activates PI3kinase via scavenger receptor-B1. by Yagna P. R. Jarajapu (316562)

Changes in EPSC parameters have little effect on the ISI distribution. by Trystan Leng (4229680)

“…(<b>A)</b> Increasing the EPSC magnitude (Δ_epsc) slightly increases the number of short ISIs, shifting the distribution to the left, with a small decrease in the height of the mode. Plotted distributions are for EPSP magnitudes of ~ 1, 2, 3, and 4 mV (darkest to lightest). …”

greenhouse experiment analysis script by Brittany Cavazos (17226175)

Dynamics of the Ca²⁺ depletion waves. by Mitra Esfandiarei (280455)

Axon misguidance phenotypes in vivo occur where the Shh gradient is shallow. by Tyler F. W. Sloan (715369)

“…<p><b>(A)</b> Mouse e9.5 (left) and e10.5 (middle and right) spinal cord cross-sections immunostained for Shh. …”

Are Standard Follow-Up Parameters Sufficient to Protect Neurocognitive Functions in Patients with Diabetes Mellitus who Underwent Coronary Artery Bypass Grafting? by Hakan Sacli (8618775)

Supplementary Material for: Forecasting the Worldwide Impact of Stroke for individuals aged 45 and above by Fan W. (11417327)

Supplemental Figs. S1-S7 by Carolyn Morris (21298187)

Cephalometric changes during aging in subjects with normal occlusion by Daniela GARIB (12682165)

Effect of remediation technologies on soil fertility in heavy metal(loid)-contaminated soils: A critical review by Lizhi He (6734888)

Proof of principle. by Johannes Fels (149139)

“…Cortical F-actin (#) as well as F-actin stress fibres (*) are destabilized. b) Lifeact-eGFP transfected cell (grown in a confluent monolayer of untransfected cells) treated with 50 nM CD. …”

datasheet1_In Vitro Effects of St. John’s Wort Extract Against Inflammatory and Oxidative Stress and in the Phagocytic and Migratory Activity of Mouse SIM-A9 Microglia.pdf by Gabriel A. Bonaterra (8584485)

“…Besides, pre-treatment (48 h) of microglia with STW3-VI (5 or 10 μg/ml) or desipramine (5 µM) inhibited the NMDA-induced decrease of the viability by 16.5–28.8% or 12%, respectively. …”

image1_In Vitro Effects of St. John’s Wort Extract Against Inflammatory and Oxidative Stress and in the Phagocytic and Migratory Activity of Mouse SIM-A9 Microglia.tif by Gabriel A. Bonaterra (8584485)

“…Besides, pre-treatment (48 h) of microglia with STW3-VI (5 or 10 μg/ml) or desipramine (5 µM) inhibited the NMDA-induced decrease of the viability by 16.5–28.8% or 12%, respectively. …”

datasheet2_In Vitro Effects of St. John’s Wort Extract Against Inflammatory and Oxidative Stress and in the Phagocytic and Migratory Activity of Mouse SIM-A9 Microglia.pdf by Gabriel A. Bonaterra (8584485)

“…Besides, pre-treatment (48 h) of microglia with STW3-VI (5 or 10 μg/ml) or desipramine (5 µM) inhibited the NMDA-induced decrease of the viability by 16.5–28.8% or 12%, respectively. …”

datasheet1_In Vitro Effects of St. John’s Wort Extract Against Inflammatory and Oxidative Stress and in the Phagocytic and Migratory Activity of Mouse SIM-A9 Microglia.pdf by Gabriel A. Bonaterra (8584485)

“…Besides, pre-treatment (48 h) of microglia with STW3-VI (5 or 10 μg/ml) or desipramine (5 µM) inhibited the NMDA-induced decrease of the viability by 16.5–28.8% or 12%, respectively. …”

datasheet2_In Vitro Effects of St. John’s Wort Extract Against Inflammatory and Oxidative Stress and in the Phagocytic and Migratory Activity of Mouse SIM-A9 Microglia.pdf by Gabriel A. Bonaterra (8584485)

“…Besides, pre-treatment (48 h) of microglia with STW3-VI (5 or 10 μg/ml) or desipramine (5 µM) inhibited the NMDA-induced decrease of the viability by 16.5–28.8% or 12%, respectively. …”