Showing 1,481 - 1,500 results of 61,176 for search '(( 50 ((n decrease) OR (a decrease)) ) OR ( 5 ((we decrease) OR (nn decrease)) ))', query time: 1.50s Refine Results
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    Expressed A-p50 exhibits biological activity in A549 cells by Jing Mi (18654)

    Published 2011
    “…Ad-A-p50-infected A549 cells show a decrease in nuclear NF-κB p50 expression (Ad-A-p50) compared with Ad-siNT-infected A549 cells. …”
  7. 1487

    N2142A mutation reduced viral replication and binding to cell by impairing receptor binding. by Xue Li (285380)

    Published 2023
    “…<b>(C)</b> The fraction #10 samples of CVA10-WT and CVA10-N142A were diluted to 50 μg/ml and subjected to negative stain electron microscopy. …”
  8. 1488

    A Genome-Wide Association Study Uncovers a Genetic Locus Associated with Thoracic-to-Hip Ratio in Koreans by Seongwon Cha (107939)

    Published 2015
    “…In the initial discovery stage, there was a statistically nominal association between minor alleles of SNP markers on chromosomes 4, 8, 10, and 12, and THR changes (p < 5.0 × 10<sup>−6</sup>). …”
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    Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

    Published 2021
    “…Here, by addressing a high-energy water, we improved the IC<sub>50</sub> value of our co-crystallized glycogen synthase kinase-3β (GSK-3β) inhibitor by nearly two orders of magnitude. …”
  13. 1493

    Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors by Stanislav Andreev (11067165)

    Published 2021
    “…Here, by addressing a high-energy water, we improved the IC<sub>50</sub> value of our co-crystallized glycogen synthase kinase-3β (GSK-3β) inhibitor by nearly two orders of magnitude. …”
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    Design, Synthesis, and Biological Evaluation of Indoline and Indole Derivatives as Potent and Selective α<sub>1A</sub>-Adrenoceptor Antagonists by Fei Zhao (183673)

    Published 2016
    “…In this study, two highly selective and potent α<sub>1A</sub>-AR antagonists, compounds (<i>R</i>)-<b>14r</b> (IC<sub>50</sub> = 2.7 nM, α<sub>1B</sub>/α<sub>1A</sub> = 640.1, α<sub>1D</sub>/α<sub>1A</sub> = 408.2) and (<i>R</i>)-<b>23l</b> (IC<sub>50</sub> = 1.9 nM, α<sub>1B</sub>/α<sub>1A</sub> = 1506, α<sub>1D</sub>/α<sub>1A</sub> = 249.6), which exhibited similar activities and better selectivities in cell-based calcium assays as compared with the marketed drug silodosin (IC<sub>50</sub> = 1.9 nM, α<sub>1B</sub>/α<sub>1A</sub> = 285.9, α<sub>1D</sub>/α<sub>1A</sub> = 14.4), were identified. …”
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