Iminosugar-based GCS inhibitors decrease brain GFAP positive cells. by Karen M. Ashe (349018)

Iminosugar-based GCS inhibitors decrease brain α-synuclein aggregates. by Karen M. Ashe (349018)

Decreased number of cones and retinal ganglion cells in Oc-deficient retina. by Michaela Kreplova (9239560)

NTF effect on neuronal morphologies Effect of 50 ng/ml BDNF, 100 ng/ml CNTF and the combination of both NTFs (B/C) compared to negative control (NC) on neuronal morphology in terms... by Jana Schwieger (782065)

The effect of transcription inhibition on UV sensitivity is decreased after serum starvation. by Ivaylo Stoimenov (222016)

<i>B-MOBILE</i> - A Smartphone-Based Intervention to Reduce Sedentary Time in Overweight/Obese Individuals: A Within-Subjects Experimental Trial by Dale S. Bond (588506)

“…However, few sedentary-reducing interventions exist and none have utilized smartphones to automate behavioral strategies to decrease SED. We tested a smartphone-based intervention to monitor and decrease SED in overweight/obese individuals, and compared 3 approaches to prompting physical activity (PA) breaks and delivering feedback on SED.…”

In vitro characterization of MAb-1D8 activity. by Nanae Nagata (3916574)

Subjects:

GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) by F. Anthony Romero (2452198)

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Lichen species richness (LSR) model summarized by distance class from the DMTS haul road in CAKR. by Peter N. Neitlich (4034300)

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Nonmetric multidimensional scaling ordination of lichen plots at distances 10 m through 4000 m from the DMTS haul road in Cape Krusenstern National Monument, Alaska. by Peter N. Neitlich (4034300)

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Design, Synthesis, and Biological Evaluation of Indoline and Indole Derivatives as Potent and Selective α_1A-Adrenoceptor Antagonists by Fei Zhao (183673)

“…In this study, two highly selective and potent α_1A-AR antagonists, compounds (<i>R</i>)-<b>14r</b> (IC₅₀ = 2.7 nM, α_1B/α_1A = 640.1, α_1D/α_1A = 408.2) and (<i>R</i>)-<b>23l</b> (IC₅₀ = 1.9 nM, α_1B/α_1A = 1506, α_1D/α_1A = 249.6), which exhibited similar activities and better selectivities in cell-based calcium assays as compared with the marketed drug silodosin (IC₅₀ = 1.9 nM, α_1B/α_1A = 285.9, α_1D/α_1A = 14.4), were identified. …”

Photos of <i>Hylocomium splendens</i> moss and <i>Peltigera</i> sp. lichen from 10 m vs 4000 m away from the DMTS haul road in Cape Krusenstern National Monument, Alaska. by Peter N. Neitlich (4034300)

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Hypoxia decreases H3-Ace and increases HDAC1 expression. by Zheng Wang (25883)

Decreased pMHC avidity and CD8β-independence for functional avidity of D^bNPN3A-primed T cells for D^bNP₃₆₆. by Sophie A. Valkenburg (176257)

HAART decreases Viral Load and increases CD4 counts and percentages. by Pietro Presicce (144163)

Umbelliprenin treatment decreases the activity of the TCF reporter in gastric cancer cells. by Lijing Zhang (463702)

Cellular uptake of [¹⁴C]docosahexaenoic acid (DHA) by RBECs transfected with MFSD2A siRNA. by Takuro Iwao (14636741)

Conditions that ablate cytonemes decrease signaling, reduce myoblast and tumor growth. by Sol Fereres (664350)

Ammonium decreases apparent root meristem size and the number of dividing cells. by Ying Liu (18461)

Substitution of a lysine residue at position 8 of two model 9mer H2-K^b epitope precursors leads to a marked decrease of N-terminus trimming by ERAP1 <i>in vitro</i>. by Irini Evnouchidou (375919)

“…<p><i>Panels </i><i>A</i><i> and </i><i>B</i>, peptides LSIINFEKL and the variant LSIINFEAL (both at 50 µM) were incubated with 7.8 nM of ERAP1 for 1 hr at 37°C and the products analyzed by RP-HPLC. …”