Loss of ALS2 results in decreased levels of the lysosome-dependent degradation of LC3 in fibroblasts. by Shinji Hadano (251529)

“…Fibroblasts from wild-type (WT) and <i>Als2</i>^−/− mice were either left unstarved (0 hr) (upper) or starved for 6 hr (lower). It is notable that a 6 hr of starvation leads to decreased levels of the LC3- and p62-immunoreactive signals in WT cells, but not in <i>Als2</i>^−/− cells. …”

PLD1 inhibition decreases the c-Myc-dependent dNTP biosynthetic transcriptional program. by Harry E. Taylor (596259)

siATF2 treatment decreases γ-globin gene expression in K562 cells. by Li Liu (75607)

The <i>rcan-1</i> rearrangement allele decreases expression of <i>rcan-1</i>. by Yuehui Zhao (3146229)

“…<p>(A) A volcano plot of expression differences between the <i>rcan-1</i> NIL1 and N2* strains. …”

The treatment with anti-CXCR3 decreases the number of CD8⁺ T cells in the heart. by Camila Pontes Ferreira (6194006)

TBEV-induced translational arrest results in the decreased protein levels of GAPDH, HPRT1, and viperin. by Martin Selinger (3195987)

Binding sensogram (a) showing decrease in frequency of crystal immobilised with 1.5 M short aptamer exposed to different concentrations of heparanase. by Suzanne C. Simmons (319222)

Identification, Synthesis, and Biological Evaluations of Potent Inhibitors Targeting Type I Protein Arginine Methyltransferases by Xiao Li (107004)

“…In this study, we first identified several hit compounds against CARM1 by structure-based virtual screening (IC₅₀ = 35.51 ± 6.68 to 68.70 ± 8.12 μM) and then carried out chemical structural optimizations, leading to six compounds with significantly improved activities targeting CARM1 (IC₅₀ = 18 ± 2 to 107 ± 6 nM). …”

IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors by Alexandra Cousido-Siah (777034)

“…Next, by means of IC₅₀ measurements, X-ray crystallography, WaterMap analysis, and advanced binding free energy calculations with a quantum-mechanical (QM) approach, we have studied their structure–activity relationship (SAR) against both enzymes. …”

Sexual symptoms, (N = 73). by Wafa Y. Ahmed (20727327)

“…<div><p>Deinfibulation [opening the scar of infibulation] is a minor operation involving a vertical incision to the scar to expose the urethra and vagina. …”

Shapefiles of canopy disturbances for the 50-ha plot on Barro Colorado Island, Panama, for 2014-2019 by Raquel F. Araujo (10648181)

“…We defined a canopy disturbance as a substantial decrease in canopy height in a contiguous patch of canopy occurring over one measurement interval. …”

IVIg does not decrease the antibody response against a thymus-independent antigen but recruits mature B cells to draining lymph nodes. by Laetitia Sordé (511583)

The SNP (rs2230500) in <em>PRKCH</em> Decreases the Risk of Carotid Intima-Media Thickness in a Chinese Young Adult Population by Lijun Wu (152858)

The numerical values underlying Fig 4. by Wataru Matsunaga (3452621)

“…However, only the KO mice showed a significant decrease in rotarod performance of 1.2 g/kg EtOH. …”

Introduction of the F region into CA-MRSA strains attenuates virulence in a mouse systemic infection model and decreases colony-spreading ability. by Chikara Kaito (230958)

Polarized localization of lipid bodies and starch granules visualized by transmission electron microscopy. by Steve Dagenais Bellefeuille (654383)

Topography of the relationship between the change in alpha power decrease and the change in M50 gating ratio. by Tzvetan Popov (315385)

“…B: Relationship between change in alpha power decrease (abscissa, negative values indicate improvement) and pre-to-post-training change in M50 gating ratio (ordinate, positive values indicate changes towards normal, that is, smaller gating ratio) by patient training group based on the ROI in 4A.…”

DataSheet1_Decreasing viscosity and increasing accessible load by replacing classical diluents with a hydrotrope in liquid–liquid extraction.docx by Asmae El Maangar (19690522)

“…We show that using hydrotropes as a diluent decreases the viscosity of solutions by more than a factor of ten, even under high load by extracted cations. …”

<i>In vitro</i> IC₅₀ values (nM) for fatty acid desaturases. by Hiroaki Yashiro (2231686)

Diagnostic performance of blood parameters to discriminate abnormal from normal MAD activity (A) and decreased from absent MAD activity (B). by Fabrice Rannou (775170)

“…(B) Classifiers for the differentiation of Absent (n = 5) from Decreased (n = 6) MAD activity. 50% PMP: 50% from predicted maximal power (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0132972#sec006" target="_blank">Methods</a>), R: Recovery from exercise, Se: Sensibility, Sp: Specificity, Acc: Accuracy, PPV: Positive predictive value, NPV: Negative predictive value, LR+: Positive likelihood ratio, LR-: Negative likelihood ratio, DOR: Diagnostic odds ratio, NC: Not calculable.…”