A Minor (<50%) Signet-Ring Cell Component Associated with Poor Prognosis in Colorectal Cancer Patients: A 26-Year Retrospective Study in China by Yinuo Tan (705777)

“…<div><p>Background</p><p>We performed a retrospective study to determine the cancer-specific survival of colorectal cancer patients with a component of signet-ring cells or mucin comprising < 50% of the tumor mass.…”

The stereochemical configurations at the C2 and C6 carbons of hydroxynorketamine (HNK) affect the concentration-dependent decrease in intracellular D-Ser concentration in PC-12 cel... by Nagendra S. Singh (2620399)

Morpholine antisense oligonucleotide treatment decreases expression of the flow-responsive gene <i>klf2a</i> results in valve dysgenesis. by Julien Vermot (257990)

“…(K and L) <i>notch1b</i> expression at 48 hpf decreases in the AV boundary of the <i>klf2a</i> morphants (<i>n</i> = 45, 71%). …”

Pre-treatment of IOZCAS-Spex-II cells with CPT and HCPT decreased Topo1 specific activity in a dose-dependent manner. by Lan Zhang (90951)

K562 cells were treated with 40 nM of miR-214 mimics or a negative mimics control for 24 h, followed by treatment with 50 μM of hemin for 48 h. by Tipparat Penglong (164413)

Dexmedetomidine (Dex) reversed isoflurane-induced inhibition of Akt activity and decrease of Bcl-xL/Bad ratio in the hippocampus of P7 rats (n = 7 in each group). by Yujuan Li (554062)

Neural networks classify states which differ in neuronal activity levels using ensembles of neurons that increase/decrease their activity in each state. by Nicholas A. Frost (10739821)

“…As a result, there is an increase (neurons 51:100) or decrease (neurons 1:50) in activity levels in State B compared to State A. …”

Boxplot showing differences in vertebral cross-sectional growth between girls with increased (<i>n</i> = 14) and decreased vertebral body wedging (<i>n</i> = 13); <i>p</i> = 0.001. by Ervin Poorghasamians (3801475)

TR4 and TR9 decrease hepatoma cell viability at a lower TC50 than Sorafenib, SAHA or 5-Fluorouracil. by Nicole Lange (335740)

A Yoga Strengthening Program Designed to Minimize the Knee Adduction Moment for Women with Knee Osteoarthritis: A Proof-Of-Principle Cohort Study by Elora C. Brenneman (795723)

“…A secondary objective was to determine whether the program could improve mobility and fitness, and decrease peak KAM during gait. …”

Tacrolimus Decreases Albuminuria in Patients with IgA Nephropathy and Normal Blood Pressure: A Double-Blind Randomized Controlled Trial of Efficacy of Tacrolimus on IgA Nephropathy by Yong-Chul Kim (1637572)

“…We randomly assigned patients either to receive tacrolimus or placebo with stratification by using a renin angiotensin system blocker. …”

DataSheet_1_Hemizygous nonsense variant in the moesin gene (MSN) leads to a new autoimmune phenotype of Immunodeficiency 50.pdf by András L. Kovács (13565251)

“…We present a putative new autoimmune phenotype of Immunodeficiency 50 (MIM300988) characterized by antiphospholipid syndrome, Hashimoto’s thyroiditis, leg ulcers, and juvenile tooth loss, associated with W217X mutation of the MSN gene.…”

Table_2_Move for Life an intervention for inactive adults aged 50 years and older: a cluster randomised feasibility trial.DOCX by Catherine B. Woods (10517765)

“…Background<p>Move for Life (MFL) is a theory-informed intervention that was developed to augment established physical activity (PA) programmes and enable inactive adults aged 50 years and older to be more active. …”

Table_1_Move for Life an intervention for inactive adults aged 50 years and older: a cluster randomised feasibility trial.DOCX by Catherine B. Woods (10517765)

“…Background<p>Move for Life (MFL) is a theory-informed intervention that was developed to augment established physical activity (PA) programmes and enable inactive adults aged 50 years and older to be more active. …”

Intracellular images (×20000) of <i>S</i>. <i>cerevisiae</i> strain BH8 before (a) and after (b, c) culturing in MSM with 1.50 mM Cu²⁺ for 48 h; CW: cell wall; N: cell n... by Xiang-yu Sun (748032)

Upregulation of autophagy decreases the age-related accumulation of hyperphosphorylated tau and ameliorates tau-induced locomotor defects in human Tau (0N3R) expressing transgenic... by Shreyasi Chatterjee (3531506)

Localization of key HH signaling proteins is impaired in <i>Ttbk2</i>^{<i>sca11/gt</i>} cilia. by Emily Bowie (543704)

BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell by Jude T. Deeney (335344)

“…JQ1 (50–400 nM) increases insulin secretion from INS-1 cells in a concentration dependent manner. …”

Effect of melatonin (50 μM) on the TGF-β1 (10 ng/mL, 72 h)-mediated TGF-β1/Smad pathway and EMT in HBdSMCs. by Yang Zhang (30734)

Influence of ghrelin treatment (0.5 μg/g BW, twice a day, intraperitoneal (ip.)) on bacterial load after cecal ligation and puncture (CLP)-induced sepsis. by Daniel Siegl (717509)