BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell by Jude T. Deeney (335344)

“…JQ1 (50–400 nM) increases insulin secretion from INS-1 cells in a concentration dependent manner. …”

Effect of melatonin (50 μM) on the TGF-β1 (10 ng/mL, 72 h)-mediated TGF-β1/Smad pathway and EMT in HBdSMCs. by Yang Zhang (30734)

rhIL-4 and rhIL-13 decrease LEC proliferation and downregulate expression of Prox-1. by Ira L. Savetsky (749034)

Influence of ghrelin treatment (0.5 μg/g BW, twice a day, intraperitoneal (ip.)) on bacterial load after cecal ligation and puncture (CLP)-induced sepsis. by Daniel Siegl (717509)

Influence of ghrelin treatment (0.5 μg/g BW, twice a day, intraperitoneal (ip.)) on inflammatory mediators after cecal ligation and puncture (CLP)-induced sepsis. by Daniel Siegl (717509)

Intravenous treatment of naïve wild-type mice with PrP LSPCs decreased PrP^C mRNA and cell surface PrP^C protein at various time points. by Heather Bender (363996)

Structurally distinct inhibitors of Chk1 decrease Chk1 nuclear fluorescence following heating in a low well volume. by Andrew J. Massey (239469)

The decrease of C/EBPα protein during apoptosis involves induction of protein degradation and inhibition of transcription. by Meng Zhao (54299)

“…<p>(A) After pretreatment with 25 nM of NSC606985 or 0.5 µM of etoposide for 12 hours, NB4 cells were incubated with 10 µg/ml CHX for indicated hours. …”

ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulat... by Rodrigo A Fuentealba (77901)

“…In N2a cells almost all PS1 is detected as PS1-NTF but in CHO LRP1-null cells a significant amount of Holo-PS1 is also detected. …”

Summary plot for the effect of important food sources of fructose-containing sugars on diastolic blood pressure (DBP). by Qi Liu (33068)

Fixation becomes unlikely with decreasing fitness of mutant homozygotes, variance in allele frequency increases with migration rate. by Philipp M. Altrock (340203)

Decrease in the hemolymph sugar level of hyperglycemic silkworms and increase in Akt phosphorylation in the fat body by human insulin. by Yasuhiko Matsumoto (206628)

Influence of ghrelin treatment (0.5 μg/g BW, twice a day, intraperitoneal (ip.)) on early cytokine response after cecal ligation and puncture (CLP)-induced sepsis. by Daniel Siegl (717509)

Commensal bacteria decrease yeast appetite upon essential amino acid (eAA) deprivation and are phagostimulators. by Ricardo Leitão-Gonçalves (3949604)

The ¹H−¹⁵N HSQC spectra overlay of free ¹⁵N p53 (1–73) (red) and in complex with unlabelled S100A1 (yellow). by Deepu Dowarha (5673440)

siRNA-mediated depletion of CUL5 in HUVEC prevents thalidomide-dependent decrease in cellular proliferation. by Bryan Kunkler (5204327)

Increased GLB1 correlates with decreased proliferation and increased expression of HP1γ in benign tissue. by Jennifer Wagner (523883)

Wild-type SPOP increases, and the prostate cancer-associated SPOP mutants decrease, mitochondria average length. by Xiaofeng Jin (646436)

Deformation of buried DN50 PE pipeline exposed to 5000 kN/m² stacking load with various buried depths. by Pengcheng Li (123281)

Growth curves (A, strain AWRI R2 (A); B, strain BH8 (B); C, strain Freddo (F)) and accumulated fermentation system mass loss(D, strain A; E, strain B; F, strain F) of <i>S</i>. <i>... by Xiang-yu Sun (748032)