Data Sheet 1_Identification of a multiple DAMP scavenger mimicking the DAMP-binding site of TLR4 to ameliorate lethal sepsis.pdf by Takuya Murao (114383)

“…OP18 was developed by identifying a 15-amino acid (aa) binding site within the extracellular domain of Toll-like receptor 4 (TLR4) shared by eCIRP, HMGB1, and histone H3, then extending it with an α_vβ₃-integrin binding RGD (Arg-Gly-Asp) motif, resulting in an 18-aa peptide. …”

Supplementary Material for: Iron Regulation by Molidustat, a Daily Oral Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor, in Patients with Chronic Kidney Disease by Akizawa T. (3588626)

Supplementary Material for: Exploring the Impact of Age and Pre-Stroke Modified Rankin Scale in Elderly Thrombectomy: a 15-year Single Center Experience by Enriquez B.A.B. (19450969)

Data from: "Reproductive tradeoffs in a perennial crop: Exploring the mechanisms of coffee alternate bearing in relation to farm management." Agriculture, Ecosystems, and Environme... by Gabriela Garcia (10917540)

Correlation between the RS rate and temperature. by Yueqin Chen (5811368)

“…The experimental results showed that low nitrogen addition rate (5 g·m^-2·yr^-1) increased soil respiration rate by about 11% in summer, but decreased it by about 6% in winter, with a range of 5% to 20%. …”

Schematic diagram of experimental area selection. by Yueqin Chen (5811368)

“…The experimental results showed that low nitrogen addition rate (5 g·m^-2·yr^-1) increased soil respiration rate by about 11% in summer, but decreased it by about 6% in winter, with a range of 5% to 20%. …”

Influence of N-addition on soil RH. by Yueqin Chen (5811368)

“…The experimental results showed that low nitrogen addition rate (5 g·m^-2·yr^-1) increased soil respiration rate by about 11% in summer, but decreased it by about 6% in winter, with a range of 5% to 20%. …”

Image_1_Biosynthesis of Silver Nanoparticles by Marine Actinobacterium Nocardiopsis dassonvillei and Exploring Their Therapeutic Potentials.jpg by Maha A. Khalil (11454121)

“…In vitro studies using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay revealed a concentration-dependent decrease in cell viability when CaCo2 cells were exposed to Bio-AgNPs. …”

DataSheet1_Voluntary wheel running reduces tumor growth and increases capillarity in the heart during doxorubicin chemotherapy in a murine model of breast cancer.pdf by Tytti-Maria Uurasmaa (13267149)

“…Two weeks later, doxorubicin treatment was started via intraperitoneal administration (5 mg/kg weekly for 3 weeks). Organs were harvested a day after the last dose.…”

Image4_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Image6_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Image3_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Table2_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.DOCX by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Image1_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Table4_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.docx by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Image2_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Image7_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.JPEG by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Table3_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.docx by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Table1_The galectin-3 inhibitor selvigaltin reduces liver inflammation and fibrosis in a high fat diet rabbit model of metabolic-associated steatohepatitis.docx by Paolo Comeglio (14195007)

“…Selvigaltin (previously known as GB1211) is a novel orally active galectin-3 small molecule inhibitor that has high affinity for galectin-3 (human K_D = 25 nM; rabbit K_D = 12 nM) and high oral bioavailability in rabbits and man. …”

Dilated endoplasmic reticulum and altered Golgi distribution in patient cells suggest an intracellular trafficking defect. by Ronit Marom (4454017)