Synthesis and Biological Evaluation of MEK/mTOR Multifunctional Inhibitors as Novel Anticancer Agents by Marcian E. Van Dort (21374093)

Subjects:

The position of the mutations I989T, V992M and V997M in the ACE C domain. by Olga V. Kryukova (19819428)

Subjects:

FGFR3/fibroblast growth factor receptor 3 inhibits autophagy through decreasing the ATG12–ATG5 conjugate, leading to the delay of cartilage development in achondroplasia by Xiaofeng Wang (119575)

“…Furthermore, we found that FGFR3 interacted with ATG12–ATG5 conjugate by binding to ATG5. …”

NO donors and Bradykinin increase 26S proteasome reporter protein levels and decrease 26S proteasome activity. by Hongtao Liu (114450)

Decreased Tks5 expression results in neural crest-derived defects. by Danielle A. Murphy (212554)

“…<p>(A–B) Melanophores within the trunk region above the yolk sac extension in control MO-injected and Tks5 MO-injected embryos were qualitatively (A) and quantitatively (B) analyzed. n = 15 embryos and SEM is shown by bar. p values obtained from Student's t-test. ** denotes p<0.01. …”

Heart specific RNase Z variants show a mild decrease in longevity and locomotor response. by Ekaterina Migunova (15909887)

DataSheet3_Rhubarb Enema Decreases Circulating Trimethylamine N-Oxide Level and Improves Renal Fibrosis Accompanied With Gut Microbiota Change in Chronic Kidney Disease Rats.PDF by Chunlan Ji (5712218)

“…</p><p>Conclusion: Rhubarb enema decreases circulating TMAO level and improves renal fibrosis in 5/6Nx CKD rats, which may be related to the regulation of intestinal microbial community.…”

DataSheet4_Rhubarb Enema Decreases Circulating Trimethylamine N-Oxide Level and Improves Renal Fibrosis Accompanied With Gut Microbiota Change in Chronic Kidney Disease Rats.docx by Chunlan Ji (5712218)

“…</p><p>Conclusion: Rhubarb enema decreases circulating TMAO level and improves renal fibrosis in 5/6Nx CKD rats, which may be related to the regulation of intestinal microbial community.…”

DataSheet2_Rhubarb Enema Decreases Circulating Trimethylamine N-Oxide Level and Improves Renal Fibrosis Accompanied With Gut Microbiota Change in Chronic Kidney Disease Rats.PDF by Chunlan Ji (5712218)

“…</p><p>Conclusion: Rhubarb enema decreases circulating TMAO level and improves renal fibrosis in 5/6Nx CKD rats, which may be related to the regulation of intestinal microbial community.…”

DataSheet1_Rhubarb Enema Decreases Circulating Trimethylamine N-Oxide Level and Improves Renal Fibrosis Accompanied With Gut Microbiota Change in Chronic Kidney Disease Rats.PDF by Chunlan Ji (5712218)

“…</p><p>Conclusion: Rhubarb enema decreases circulating TMAO level and improves renal fibrosis in 5/6Nx CKD rats, which may be related to the regulation of intestinal microbial community.…”

FA decrease in 5STS impaired participants. by Charlotte Bernard (433013)

FSS rescues homocysteine-caused the decrease of NO production in cultured HUVECs after the application of A23187. by Cathy W. C. Bi (108697)

EPO administration does not decrease <i>Hamp</i> expression in <i>mask</i> mice. by Jana Frýdlová (163557)

Chronic high glucose induces apoptosis and proteasome activities decrease in INS-1E cells. by Christophe Broca (538652)

Decrease in the hemolymph sugar level of hyperglycemic silkworms and increase in AMPK phosphorylation in the fat body by AICAR. by Yasuhiko Matsumoto (206628)

Blocking C5L2 decreased C5a-primed neutrophils expression of membrane-bound PR3 (mPR3). by Jian Hao (160736)

H₂S is responsible for decreased active MMP-1/TIMP-1 ratio. by Ingrid Gomez (520676)

H₂S is responsible for decreased active MMP-1/TIMP-2 ratio. by Ingrid Gomez (520676)

A. We randomly selected 20 mutually exclusive groups of protein complexes that contained exactly five subunits; we mapped the corresponding gene pairs to SINaTRA scores, and plotte... by Alexandra Jacunski (5665486)

“…A SINaTRA cutoff of 0.95 has approximately half of its pairs associated with the same complex; however, a decrease in the cutoff shifts this balance. …”

DataSheet_1_Imiquimod Boosts Interferon Response, and Decreases ACE2 and Pro-Inflammatory Response of Human Bronchial Epithelium in Asthma.pdf by Juan José Nieto-Fontarigo (11800142)

“…Background<p>Both anti-viral and anti-inflammatory bronchial effects are warranted to treat viral infections in asthma. We sought to investigate if imiquimod, a TLR7 agonist, exhibits such dual actions in ex vivo cultured human bronchial epithelial cells (HBECs), targets for SARS-CoV-2 infectivity.…”