Showing 621 - 640 results of 106,112 for search '(( 50 ((n decrease) OR (mean decrease)) ) OR ( 5 ((we decrease) OR (a decrease)) ))', query time: 1.67s Refine Results
  1. 621

    Elevated IDO activity in HD mouse brains is decreased by <i>ex-vivo</i> iron chelation. by David W. Donley (3111198)

    Published 2021
    “…</b> Striatal IDO activity is increased in N171-82Q HD mice and significantly decreased by <i>ex vivo</i> iron (III) chelation (50 μM deferoxamine). …”
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    Conditional stabilization of β-catenin decreases frequency of Tbr2-expressing cells. by Christopher A. Mutch (243132)

    Published 2010
    “…This analysis also resulted in a markedly decreased Tbr2+ intermediate progenitor population in cortices (<b>F</b>) when compared to NesCre- control. …”
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    Activated CD8 T cells in FOXO3−/− mice display decreased apoptosis. by Jeremy A. Sullivan (183868)

    Published 2012
    “…<p>To address whether the increase in antigen-specific cells observed in FOXO3−/− mice at day 8 was in fact the result of decreased apoptosis, we assessed the relative expression levels of a number of cell survival or cell death markers. …”
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    Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

    Published 2021
    “…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”
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    Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... by Shuai Wang (109515)

    Published 2021
    “…Here, we reported our medicinal chemistry efforts that led to the discovery of the triazolo­[1,5-<i>a</i>]­pyrimidine derivative <b>WS-898</b> as a highly effective ABCB1 inhibitor capable of reversing paclitaxel (PTX) resistance in drug-resistant SW620/Ad300, KB-C2, and HEK293/ABCB1 cells (IC<sub>50</sub> = 5.0, 3.67, and 3.68 nM, respectively), more potent than verapamil and zosuquidar. …”
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    The injectable contraceptives depot medroxyprogesterone acetate and norethisterone enanthate substantially and differentially decrease testosterone and sex hormone binding globulin... by Chanel Avenant (409756)

    Published 2025
    “…Both contraceptives substantially decreased, from D0 to 25W, the total testosterone [DMPA-IM D0 0.560, 25W 0.423 nmol/L, -24.3% (p < 0.0001); NET-EN D0 0.551, 25W 0.253 nmol/L, -54.1%, (p < 0.0001)], SHBG [DMPA-IM D0 45.0, 25W 32.7 nmol/L, -29.8% (p < 0.0001); NET-EN D0 50.2, 25W 17.6 nmol/L, -65.1% (p < 0.0001)], and calculated free testosterone levels [DMPA-IM D0 6.87, 25W 5.38 pmol/L, -17.2% (p = 0.0371); NET-EN D0 6.00, 25W 3.70, -40.0% (p < 0.0001)]. …”
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    Activation of Wnt/β-catenin signaling decreases mRNA expressions of <i>Scx</i>, <i>Mkx</i> and <i>Tnmd</i> in rat TDCs. by Yasuzumi Kishimoto (4282138)

    Published 2017
    “…<p>Relative expressions of <i>Axin2</i>, <i>Scx</i>, <i>Mkx</i>, and <i>Tnmd</i> in TDCs treated with 50 ng/ml Wnt3a with or without 5 μM IWR (an inhibitor of β-catenin) <b>(A)</b>, 0 to 4 μM BIO (an activator of β-catenin) <b>(B)</b>, or 0 to 20 μM IWR <b>(C)</b> for 72 hrs. …”
  18. 638

    Image_5_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif by Takahiko Akagi (13138338)

    Published 2022
    “…T79M is a known mutation responsible for TRAPS, whereas G87V is a TRAPS mutation that we have reported, and T90I is a variant of unknown significance. …”
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