Method for the Large-Scale Synthesis of Multifunctional 1,4-Dihydro-pyrrolo[3,2‑<i>b</i>]pyrroles by Mariusz Tasior (1457731)

“…The conditions identified (first step: toluene/AcOH = 1:1, 1 h, 50 °C; second step: toluene/AcOH = 1:1, Fe­(ClO₄)₃·H₂O, 16 h, 50 °C) resulted in the formation of tetraarylpyrrolo­[3,2-<i>b</i>]­pyrroles in a 6–69% yield. …”

Effects of TP-10 treatment on pCREB and BDNF in the striatum of R6/2 mice. by Carmela Giampà (360711)

“…The intensity of pCREB immunoreactivity associated with CALB-positive cells were carried out (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0013417#s4" target="_blank">Methods</a>) on sections from wild type or R6/2 mice treated with vehicle or TP-10 (n = 6/group). A two way ANOVA indicated an overall significant effect of genotype (F(1,1008) = 103,76; p<0.0000) and treatment (F(1,1008) = 50,59; p<0.0000) and a genotype X treatment interaction (F(1,1008) = 50,59; p<0.0000). …”

IGF-1-induced enhancement of <i>PRNP</i> expression depends on the activation of PI3K-Akt signaling pathway. by Ting Liu (45625)

“…The LY294002-treated cells (lanes 2 and 6) showed a remarkable decrease in the PrP^C protein level compared with the DMSO-treated group (lanes 1 and 5). …”

Loss of <i>Hes1</i> impairs neural crest development. by Francesca Rochais (371680)

“…<p>(A) In situ hybridization at E9.5 showing decreased <i>Crabp1</i> transcript accumulation in the caudal pharyngeal region of <i>Hes1</i>^−/− compared to <i>Hes1</i>^+/+ embryos (arrowheads). …”

Structure of the Omicron epidemic waves models. by Bastien Reyné (20591988)

“…Before the emergence of the first Omicron VOC, we assume everyone has been immunised for SARS-CoV-2 (past infection or vaccination).…”

Tumor inhibition in mouse model, and effects on EGFR expression and Akt phosphorylation. by Satoshi Inoue (221875)

“…<p>(5a) Tumor growth inhibition in mice. MDA-MB-468 subcutaneous breast tumors treated systemically with P/AON/2C5, or P/AON/2C5/TfR were significantly inhibited compared with PBS (control), P(polymer only), or P/2C5 (without anti-tumor component) (P<0.03). …”

Reduced Susceptibility of DNA Methyltransferase 1 Hypomorphic (Dnmt1^N/+) Mice to Hepatic Steatosis upon Feeding Liquid Alcohol Diet by Huban Kutay (144581)

“…<div><h3>Background</h3><p>Methylation at C-5 (5-mdC) of CpG base pairs, the most abundant epigenetic modification of DNA, is catalyzed by 3 essential DNA methyltransferases (Dnmt1, Dnmt3a and Dnmt3b). …”

Data_Sheet_1_The Role of Transthoracic Echocardiography in the Evaluation of Patients With Ischemic Stroke.pdf by Robson Sarmento Teodoro (11340303)

“…The level of significance was 5%.</p><p>Results: A total of 1,100 patients (men = 606; 55.09%), with a mean age of 68.1 ± 13.3 years, were included in this study. …”

Experiment 3. by Jiehui Qian (294581)

“…There was a significant difference between the illusory decrease of bar length of Experiment 2a, 2b and Experiment 3 (<i>p</i> = 0.03).…”

Activation of ciliary channels by pregnenolone sulfate. by Steven J. Kleene (233875)

“…Each point shown is the mean of measurements in 3 to 5 cilia (without pregnenolone sulfate) or 7 to 10 cilia (with pregnenolone sulfate). …”

Effect of NK depletion on IFN-γ production in tripartite cultures. by Loke Tim Khaw (433343)

J147 Improves Learning and Short-Term Spatial Memory. by Qi Chen (144168)

“…These data show that both wild type and line 85 mice are slow learners, but that J147 corrects the deficit in both learning (day 5) and their spatial memory (probe test). (C) Aβ oligomers between 30 and 50 kD in soluble fraction from AD (left 2 lanes) and AD+J147 (right 2 lanes) animals. …”

Table_2_Responses of tree growth, leaf area and physiology to pavement in Ginkgo biloba and Platanus orientalis.xlsx by Bowen Cui (622817)

“…Relative to the vegetated land, the mean increments in the diameter at breast height and height in the paved land were significantly decreased by 44.5% and 31.9% for G. biloba and 31.7% and 60.1% for P. orientalis, respectively. …”

Cavemen Were Better at Depicting Quadruped Walking than Modern Artists: Erroneous Walking Illustrations in the Fine Arts from Prehistory to Today by Gabor Horvath (113483)

“…It decreased to 57.9% after 1887, that is in the post-Muybridgean period. …”

DataSheet1_Specific Heat Capacity of Confined Water in Extremely Narrow Graphene Nanochannels.pdf by Runfeng Zhou (10073463)

“…<p>Specific heat capacity of extremely confined water determines its performance in the heat transfer as the sizes of devices decrease to nanoscales. Here, we report the basic data of the specific heat capacity of water confined in narrow graphene nanochannels below 5 nm in height using molecular dynamics simulations. …”

Table_1_Responses of tree growth, leaf area and physiology to pavement in Ginkgo biloba and Platanus orientalis.xlsx by Bowen Cui (622817)

“…Relative to the vegetated land, the mean increments in the diameter at breast height and height in the paved land were significantly decreased by 44.5% and 31.9% for G. biloba and 31.7% and 60.1% for P. orientalis, respectively. …”

Pre-incubation of SB105-A10 either with HIV-1_IIIb or HIV-1_ada strains inhibits the viral infectivity in dilution assay. by Isabella Bon (467395)

“…Significant decrease of HIV-1 p24 amount was detectable at day 4 pi. …”

The effect of neutralizing endogenous TGF-β on RV replication. by Nicole Bedke (137686)

“…<p>PBECs from 8 asthmatic donors or 6 non-asthmatic control subjects were pretreated for 24 h in the presence of a neutralizing anti pan TGF-β antibody or isotype control antibody before infection with RV1B (1000 units/10⁵ cells) for 48 h. …”

Examples of four of the 53 stability motifs discovered by Reut Shalgi (11619)

“…Presented are mean half-life for each motif, and the -value on the hypothesis that they mediate a significant increase or decrease in half-life compared with the genome, resulting from a ranksum test. …”

Graph to show numbers of cells observed on the articular cartilage surface by Frances MD Henson (78253)

“…At day 11 and day 20 there was a significant decrease in the number of cells on the cartilage surface in the samples cultured in the presence of 100 ng/ml BMP-2 (*) compared to both control and SIL sections.…”