50% reduction of kinesin-1 perturbs the movement of APP vesicles. by Gary J. Iacobucci (192833)

“…<p>(<b>A</b>) A representative movie montage from a single neuron is shown from a primary neuronal culture expressing APP-YFP in the context of 100% kinesin-1 (APP-YFP) or 50% kinesin-1 (APP-YFP;khc²⁰−/+). …”

Relative expression of (A) miR-214 and (B) the <i>ATF4</i> target gene after transfection with 40 nM of miR-214 mimics or a negative mimics control for 24 h, followed by treatment... by Tipparat Penglong (164413)

Niphatenones block N/C interaction and inhibit expression of AR regulated genes. by Carmen A. Banuelos (636867)

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

Subjects:

Selective TASK‑1 Inhibitor with a Defined Structure–Activity Relationship Reduces Cancer Cell Proliferation and Viability by Bárbara Arévalo (4053358)

Subjects:

Affinity analysis results (with a confidence level above 50%). by Marta R. Jabłońska (8491404)

Decrease in Rac1 activity in the presence of nectin2alpha:Fc in 3-D cell aggregates. by Khameeka N. Kitt (227731)

High-throughput drug screen reveals HDAC and proteasome inhibitors as potent drug classes against synovial sarcoma. by Aimée N. Laporte (3617987)

“…<p>(A) Compounds resulting in measured relative cell viability of less than 50% are annotated as hits (blue). …”

Rac1 activity rapidly decreases upon cell-cell adhesion in 3-D cell aggregates. by Khameeka N. Kitt (227731)

“…High levels of active Rac1 at 0 minutes rapidly decreased (∼66%) within 5 minutes of cell-cell adhesion, and declined to a baseline level by 30 minutes (A). …”

HDAC inhibition prevents aggresome formation in response to proteasome inhibitors, and combination treatment leads to endoplasmic reticulum stress. by Aimée N. Laporte (3617987)

“…<p>(A) Knockdown of HDAC6 results in decreased levels of LC3B in the SYO-1 synovial sarcoma cell line. …”

NatB-inactivation decreased Drk levels through its N-terminal sequences, which was regulated by the N-end rule E3 ubiquitin ligase POE/UBR4. by Zhentao Sheng (107495)

UV irradiation does not alter cold-evoked calcium responses. by Heather N. Turner (6157268)

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

Subjects:

Ki-67 immunohistochemistry of corneal tissues. by Vindhya Koppaka (845151)

The UV-induced switch of cold-evoked behaviors requires class IV and Ch peripheral sensory neurons. by Heather N. Turner (6157268)

Cold-evoked behavioral switches and neuronal morphology after UV. by Heather N. Turner (6157268)

No change in muscle size and force, but a decrease in TB mass in 1-mo Lmna^HSA-cko mice. by Lei Xiong (334812)

BrDU labeling of corneal epithelial cells. by Vindhya Koppaka (845151)

Large amounts of ingested phenylpyruvate are required to decrease the survival of adult <i>A. gambiae</i> mosquitoes. by Silke Fuchs (506300)