Effect of age on chronic inflammation and responsiveness to bacterial and viral challenges by Ingrid Elisia (3214848)

“…These studies revealed significant differences in the levels of inflammatory markers when blood was collected in EDTA versus sodium heparin and age related differences in these biomarkers were confirmed with blood collected in EDTA from 120 healthy volunteers in 3 age categories, ie, 20 men + 20 women, aged 20–35, 36–49 and 50–77. Studies with unstimulated blood samples, to measure levels of chronic inflammation, revealed a significant increase with age in IL-12p70, CRP and PGE₂, consistent with the concept of “inflammaging”, and a decrease in G-CSF in both men and women. …”

Data_Sheet_1_Time Trends and Predictions of Suicide Mortality for People Aged 70 Years and Over From 1990 to 2030 Based on the Global Burden of Disease Study 2017.zip by Jun He (46556)

Colombian Ocular Inflammatory Diseases Epidemiology Study (COIDES): Prevalence, Incidence, and Sociodemographic Characterization of Uveitis in Colombia, 2015-2020 by Gabriela Florez-Esparza (17404252)

“…For 2020, we used a statistical model for spatial data to predict the prevalence/incidence of the diseases and compared it to the data retrieved in SISPRO.…”

Knockdown of miR-214 inhibits tumor growth in nude mice: <i>in vivo</i> functional studies. by Zi-Chen Zhang (511377)

Microglial migration increases long after the electrical silence associated with spreading depression. by Yelena Y. Grinberg (223907)

“…Specific microglial cell counts for SD movies (<i>n</i> = 5) were 0–16 cells per movie with a mean ± SEM of 7.60±2.86 cells/movie. …”

Real-time PCR quantifications in the presence of primers with different annealing abilities. by Michele Guescini (169183)

“…Each symbol represents a mean of 4 runs. SOD detected all the runs obtained using [ND1F5]≥250 nM as outliers.…”

Difference between cystatin C- and creatinine-based estimated glomerular filtration rate and incident hypertension and the mediating role of Triglyceride Glucose Index by Zixuan Zhang (6957035)

“…During a mean follow-up period of 5.0 years, 613 new cases of hypertension occurred. …”

Impact of astrocyte depletion upon non-basement membrane extracellular matrix (ECM) components. by Lisa Allnoch (10583549)

“…Immunohistochemistry detecting decorin showed a significant decrease of decorin positive area in astrocyte depleted animals compared to their controls (<b>F</b>). …”

Non-Temperature Induced Effects of Magnetized Iron Oxide Nanoparticles in Alternating Magnetic Field in Cancer Cells by Sudath Hapuarachchige (2203699)

Trio overexpression in class I da neurons. by Srividya Chandramouli Iyer (177446)

“…(<b>M</b>) Relative to control (<i>n</i> = 12), dendritic branch order analyses in vpda neurons reveals a distal shift in the percentage of higher order branching with Trio (<i>n</i> = 16) and Trio-GEF1 (<i>n = </i>16) overexpression, whereas a slight proximal shift towards lower order branching, with a steep decline in higher order branching, is observed with Trio-GEF2 overexpression (<i>n</i> = 12). …”

Data_Sheet_1_Computational Modelling of Glucose Uptake by SGLT1 and Apical GLUT2 in the Enterocyte.PDF by Nima Afshar (6582575)

“…The model results indicate that translocation of GLUT2 from the basolateral to the apical membrane increases glucose uptake into the cell; however, the reduction of efflux capacity results in a decrease in net absorption. Recruitment of GLUT2 from a cytosolic pool elicits a 10–20% increase in absorption for luminal glucose levels in the a 20–100 mM range. …”

Probability of microbe-free hosts in the stationary distribution. by Román Zapién-Campos (9592478)

Reduced mitochondrial membrane potential (ΔΨ_m) in <i>DJ-1</i>−/− MEFs. by Emilie Giaime (316501)

“…<p>(<b>A, B</b>) Confocal microscopic analysis. (<b>A</b>) Representative confocal microscopic images of <i>DJ-1</i>−/− and +/+ MEFs after staining with TMRM (50 nM, red) and Mitotracker Green (200 nM) in the presence or absence of oligomycin (Olig, 1 µM) or FCCP (10 µM). …”

Image_1_Immune Protective Evaluation Elicited by DNA Vaccination With Neospora caninum Dense Granules Proteins in Mice.TIF by Guili Yu (10201136)

“…The immune protective efficacy revealed that pcNcGRA4, pcNcGRA14, and pcNcGRA17 DNA vaccines could individually increase the survival rate to 50, 37.5, and 25% in comparison with 0% in the control group; prolong the survival time more than 20.88 ± 11.12, 18.88 ± 10.83, and 16.63 ± 10.66 days compared with the control group of 4 ± 1.31 days; and decrease parasite burden in the brains to 297.63 ± 83.77, 471.5 ± 110.74, and 592.13 ± 102.2 parasites/100 ng comparing with 1221.36 ± 269.59 parasites/100 ng in the control group. …”

Image_3_The Insulin-Sensitizer Pioglitazone Remodels Adipose Tissue Phospholipids in Humans.JPEG by Juan P. Palavicini (11780237)

Image_4_The Insulin-Sensitizer Pioglitazone Remodels Adipose Tissue Phospholipids in Humans.JPEG by Juan P. Palavicini (11780237)

Image_2_The Insulin-Sensitizer Pioglitazone Remodels Adipose Tissue Phospholipids in Humans.JPEG by Juan P. Palavicini (11780237)

Prospective Study of the Quality of Colonoscopies Performed by Primary Care Physicians: The Alberta Primary Care Endoscopy (APC-Endo) Study by Michael R. Kolber (428008)

“…Patient satisfaction was captured by a telephone survey.</p><p>Setting</p><p>Thirteen rural and suburban hospitals in Alberta, Canada.…”

Novel Core-Modified Expanded Porphyrins with <i>meso</i>-Aryl Substituents:  Synthesis, Spectral and Structural Characterization by Seenichamy Jeyaprakash Narayanan (2960982)

“…¹H NMR studies on rubyrins indicate rapid rotation of heterocyclic rings at room temperature, and protonation leads to a decrease in rate of rotation at room temperature. …”

Table_2_The Fight Against Panax notoginseng Root-Rot Disease Using Zingiberaceae Essential Oils as Potential Weapons.pdf by Yan-Jiao Yin (5816015)

“…The decreasing trend of net photosynthetic rate (P_n), stomatal conductance (g_s), intercellular CO₂ concentration (C_i), and transpiration rate (T_r) were all alleviated. …”