Random forest identified stop codon identity, P-site amino acid identity, and 3’-UTR length as factors critical in readthrough efficiency prediction. by Kotchaphorn Mangkalaphiban (9767180)

“…<p><b>A.</b> Performance metric for random forest regression displaying average Normalized Root Mean Squared Error (NRMSE) ± standard deviation across 5-fold cross-validation. …”

Effects of lycopene on ER stress inducer (thapsigargin, TG)-induced changes in neonatal cardiomyocytes. by Jiqian Xu (785333)

“…The total proteins of cardiomyocytes were extracted and the protein expression levels of Bip/GRP78 and GADD153 were detected by western blot. (A) TG evoked a dose-dependent decrease in the viability of neonatal cardiomyocytes. …”

Combination of cetuximab and trametinib was more effective in the partially responsive group ex vivo. by Takahiro Tashiro (827031)

“…E, Western blots of lysates from the reconstituted spheroids treated with or without 100 nM cetuximab, 5 nM trametinib, or a combination of 100 nM cetuximab and 5 nM trametinib for 2 h with or without stimulation with 10 ng/ml EGF for 15 min.…”

<i>In vitro</i> reductase activity with furfural and HMF as substrates in crude cell extracts from the strains MD4, MD4.1 and GVM1, the latter two each containing one copy of <i>AS... by Gert Vanmarcke (10580115)

“…For each condition, at least three technical repeats were used. (A) 2.5 mM and 5 mM furfural with NADH, (B) 5 mM furfural with NADPH, (C) 10 mM HMF with NADPH. …”

Fig 2 - by Stuart Meier (29078)

“…<p>GO annotations and KEGG pathways first enriched at (A) 13–18 and 7–12 months before diagnosis and (B) 1–6 months before diagnosis. …”

DataSheet1_Neuroprotective Effects of Oligosaccharides From Periplaneta Americana on Parkinson’s Disease Models In Vitro and In Vivo.zip by Miao-Miao Liu (347989)

“…The data demonstrated that OPA significantly reversed the MPP⁺-induced decrease in SH-SY5Y cell viability, reduced the proportion of apoptotic cells, and protected SH-SY5Y cells from apoptosis in a dose-dependent manner by regulating the expression of apoptosis-related genes. …”

CLINICAL AND RADIOLOGICAL OUTCOMES OF THE NEUROMUSCULAR SCOLIOSIS TREATMENT WITH S2-ALAR-ILIAC SCREW BY INTRAOPERATIVE NAVIGATION by Alex Oliveira de Araújo (13902391)

“…The average preoperative pelvic obliquity was 27.9°± 10.9, with a correction rate of 66.1% ± 27.6, being 8.2° ± 5.4 at the end of surgery and 9 .4°± 7.0 at the end of the follow-up. …”

Continuous mass spectrometry assay for proDer p 3 maturation by Der p 1. by Marie-Eve Dumez (461300)

“…<p>Electrospray mass spectra (positive ion mode) for 16 µM proDer p 3 activation by 0.16 µM Der p 1 in 25 mM ammonium acetate, pH 7.4, containing 1 mM DTT, obtained after 5 min (<b>A</b>) and 40 min (<b>B</b>). ProD, D and prop refer to proDer p 3, Der p 3 and propeptide, respectively. …”

MSX-122 blocks metastasis in an experimental animal model of breast cancer metastasis. by Zhongxing Liang (173875)

“…<p>(A) Representative photographs of 5 lungs were shown from each group. …”

Triple-combination therapy for cutaneous leishmaniasis using detergent-free, hyaluronate-coated elastic nanovesicles - Supplementary data set by Kashif Iqbal (6504587)

“…Materials & methods: H-ENVs were</p> <p>developed and evaluated for vesicle size, entrapment efficiency, skin permeation and antileishmanial</p> <p>potential. Results: A 15.7 and 28.6% decrease in the cytotoxicity of paromomycin and amphotericin B,</p> <p>respectively, was observed in detergent-free ENVs compared with conventional ENVs. …”

Hypoxia downmodulates TM9SF4 expression in leukemic cells. by Rosa Paolillo (736953)

“…<p>(A, B) The decrease of TM9SF4 protein expression in U937 cells (A) and in primary leukemic cells from AML M1 (B) cultured under hypoxic (1% and 5% O₂, respectively) compared to normoxic (21% O₂) conditions is shown by immunofluorescence analysis of TM9SF4. ctr- is for no primary antibody negative control. …”

Effect of exponential smoothing on recombination and identity signals along the chromosome. by Mauricio Peñuela (7138847)

“…The horizontal red line is a reference that helps to visualize the decrease of large recombination values. …”

Developmental changes in the effect of cholinergic, inhibitory and L-type voltage-gated calcium channel-dependent networks on spontaneous activity. by Abduqodir H. Toychiev (477678)

“…In contrast, regenerative compound activity revealed by SST is more prominent with age, as BC axons and inhibitory inputs mature and spontaneous currents decrease (C, red and black traces). This transition is most prominent in late second postnatal week (see text and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0077658#pone-0077658-t001" target="_blank">Table 1</a> for details). …”

Capacitance changes in response to varying proton concentrations. by Armando Carpaneto (242436)

“…Increasing the proton concentration from pH 4 to 3 at −20 mV led to a decrease of C_m as well. Subsequent application of saturating sucrose concentrations decreased C_m to similar levels as in the presence of neutral buffers. …”

Regulatory T cell suppressive function. by Joost Smolders (235367)

“…Co-culture with an increasing proportion of Treg results in an inhibition of Tresp cell proliferation (downward panels, ratio 0.25∶1, 0.5∶1, 1∶1 and 2∶1, respectively). An increasing proportion of CFSE⁻ Treg can be observed, and a subsequent decrease of proliferating CFSE⁺ Tresp cells. …”

Conservation of crisp lettuce in different post-harvest storage conditions by Mariana Izabel Schvambach (10371895)

“…There was a decrease in the parameters of fresh mass, acidity, total soluble solids, and relative content of SPAD chlorophyll in refrigerated lettuce compared to uncooled. …”

Disturbed zinc and ZIP8 homeostasis. by Eung-Kwon Pae (374276)

“…Scale bars indicate 5 µm. (E and F) Zinc taken up by the beta cells decreased in the IH group, yet not as much as the amount decreased in the siZIP8 treated cells (F). …”

α-flupentixol induces hypomotor activity and catalepsy. by Jonathan Chetrit (371852)

“…<p>(A–C) Histograms illustrating the scored motor activity recorded during the second 10 minutes session fifty minutes after the injection of saline (control) or α-flupentixol (0.3 mg/kg) or saline on day 4, 5 and 6 respectively. …”

Effect of IL-6 on Caco-2 tight junction proteins expression. by Rana Al-Sadi (541571)

“…<p>(A) IL-6 caused a time-dependent increase in claudin-2 protein expression but not claudins 3, 5, and 8 as assessed by Western Blot analysis. …”

Marimastat reversed hepatic steatosis and improved surrogate markers for insulin sensitivity in diet-induced obese mice as well as in <i>ob/ob</i> animals. by Vincent E. de Meijer (343377)

“…<p>Mean hepatic fat fraction as measured by MR spectroscopy was decreased following Marimastat treatment (A). Marimastat treatment resulted in a decrease of plasma alanine aminotransferase levels (B), indicating decreased hepatic injury. …”